IL4/STAT6 signaling activates neural stem cell proliferation and neurogenesis upon Amyloid-β42 aggregation in adult zebrafish brain P Bhattarai, AK Thomas, MI Cosacak, C Papadimitriou, V Mashkaryan, ... Cell reports 17 (4), 941-948, 2016 | 148 | 2016 |
3D culture method for Alzheimer's disease modeling reveals interleukin-4 rescues Aβ42-induced loss of human neural stem cell plasticity C Papadimitriou, H Celikkaya, MI Cosacak, V Mashkaryan, L Bray, ... Developmental cell 46 (1), 85-101. e8, 2018 | 134 | 2018 |
Single-cell transcriptomics analyses of neural stem cell heterogeneity and contextual plasticity in a zebrafish brain model of amyloid toxicity MI Cosacak, P Bhattarai, S Reinhardt, A Petzold, A Dahl, Y Zhang, C Kizil Cell reports 27 (4), 1307-1318. e3, 2019 | 103 | 2019 |
Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer’s model of adult zebrafish brain P Bhattarai, MI Cosacak, V Mashkaryan, S Demir, SD Popova, ... PLoS biology 18 (1), e3000585, 2020 | 94 | 2020 |
The effects of aging on Amyloid-β42-induced neurodegeneration and regeneration in adult zebrafish brain P Bhattarai, AK Thomas, Y Zhang, C Kizil Neurogenesis 4 (1), e1322666, 2017 | 79 | 2017 |
Focus: The aging brain: neural stem/progenitor cells in Alzheimer’s disease G Tincer, V Mashkaryan, P Bhattarai, C Kizil The Yale journal of biology and medicine 89 (1), 23, 2016 | 75 | 2016 |
Modeling amyloid-β42 toxicity and neurodegeneration in adult zebrafish brain P Bhattarai, AK Thomas, MI Cosacak, C Papadimitriou, V Mashkaryan, ... JoVE (Journal of Visualized Experiments), e56014, 2017 | 58 | 2017 |
Nerve growth factor modulates LPS-induced microglial glycolysis and inflammatory responses G Fodelianaki, F Lansing, P Bhattarai, M Troullinaki, MA Zeballos, ... Experimental cell research 377 (1-2), 10-16, 2019 | 57 | 2019 |
Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo L Reinhardt, S Kordes, P Reinhardt, M Glatza, M Baumann, HCA Drexler, ... Stem cell reports 12 (3), 502-517, 2019 | 55 | 2019 |
Alzheimer’s disease, neural stem cells and neurogenesis: cellular phase at single-cell level MI Cosacak, P Bhattarai, C Kizil Neural Regeneration Research 15 (5), 824-827, 2020 | 41 | 2020 |
Human TAUP301L overexpression results in TAU hyperphosphorylation without neurofibrillary tangles in adult zebrafish brain MI Cosacak, P Bhattarai, L Bocova, T Dzewas, V Mashkaryan, ... Scientific Reports 7 (1), 12959, 2017 | 37 | 2017 |
Efficient cargo delivery into adult brain tissue using short cell-penetrating peptides C Kizil, A Iltzsche, AK Thomas, P Bhattarai, Y Zhang, M Brand PLoS One 10 (4), e0124073, 2015 | 29* | 2015 |
FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer’s disease AJ Lee, NS Raghavan, P Bhattarai, T Siddiqui, S Sariya, ... Acta Neuropathologica, 1-21, 2022 | 27 | 2022 |
GATA3 promotes the neural progenitor state but not neurogenesis in 3D traumatic injury model of primary human cortical astrocytes H Celikkaya, MI Cosacak, C Papadimitriou, S Popova, P Bhattarai, ... Frontiers in cellular neuroscience 13, 23, 2019 | 26 | 2019 |
Is Alzheimer’s also a stem cell disease?–The zebrafish perspective C Kizil, P Bhattarai Frontiers in Cell and Developmental Biology 6, 159, 2018 | 22 | 2018 |
Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer’s Disease MI Cosacak, P Bhattarai, PL De Jager, V Menon, G Tosto, C Kizil Cells 11 (11), 1807, 2022 | 21 | 2022 |
Type 1 Interleukin-4 Signaling Obliterates Mouse Astroglia in vivo but Not in vitro V Mashkaryan, T Siddiqui, S Popova, MI Cosacak, P Bhattarai, K Brandt, ... Frontiers in Cell and Developmental Biology 8, 114, 2020 | 19 | 2020 |
Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer’s Disease B Turgutalp, P Bhattarai, T Ercetin, C Luise, R Reis, EE Gurdal, A Isaak, ... Journal of Medicinal Chemistry 65 (18), 12292-12318, 2022 | 17 | 2022 |
KYNA/Ahr Signaling Suppresses Neural Stem Cell Plasticity and Neurogenesis in Adult Zebrafish Model of Alzheimer’s Disease T Siddiqui, P Bhattarai, S Popova, MI Cosacak, S Sariya, Y Zhang, ... Cells 10 (10), 2748, 2021 | 13 | 2021 |
Zebrafish as an Experimental and Preclinical Model for Alzheimer’s Disease P Bhattarai, B Turgutalp, C Kizil ACS Chemical Neuroscience 13 (20), 2939-2941, 2022 | 11 | 2022 |