The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host G Gabriel, B Dauber, T Wolff, O Planz, HD Klenk, J Stech Proceedings of the National Academy of Sciences 102 (51), 18590-18595, 2005 | 809 | 2005 |
Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade S Pleschka, T Wolff, C Ehrhardt, G Hobom, O Planz, UR Rapp, S Ludwig Nature cell biology 3 (3), 301-305, 2001 | 645 | 2001 |
Caspase 3 activation is essential for efficient influenza virus propagation WJ Wurzer, O Planz, C Ehrhardt, M Giner, T Silberzahn, S Pleschka, ... The EMBO journal, 2003 | 435 | 2003 |
Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses C Ehrhardt, T Wolff, S Pleschka, O Planz, W Beermann, JG Bode, ... Journal of virology 81 (7), 3058-3067, 2007 | 426 | 2007 |
NF-κB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation WJ Wurzer, C Ehrhardt, S Pleschka, F Berberich-Siebelt, T Wolff, ... Journal of Biological Chemistry 279 (30), 30931-30937, 2004 | 313 | 2004 |
Bivalent role of the phosphatidylinositol‐3‐kinase (PI3K) during influenza virus infection and host cell defence C Ehrhardt, H Marjuki, T Wolff, B Nürnberg, O Planz, S Pleschka, ... Cellular microbiology 8 (8), 1336-1348, 2006 | 293 | 2006 |
Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells S Ludwig, S Pleschka, O Planz, T Wolff Cellular microbiology 8 (3), 375-386, 2006 | 273 | 2006 |
The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors S Ludwig, X Wang, C Ehrhardt, H Zheng, N Donelan, O Planz, S Pleschka, ... Journal of virology 76 (21), 11166-11171, 2002 | 272 | 2002 |
A critical role for neutralizing-antibody-producing B cells, CD4+ T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis … O Planz, S Ehl, E Furrer, E Horvath, MA Bründler, H Hengartner, ... Proceedings of the National Academy of Sciences 94 (13), 6874-6879, 1997 | 253 | 1997 |
Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF‐κB‐inhibiting activity I Mazur, WJ Wurzer, C Ehrhardt, S Pleschka, P Puthavathana, ... Cellular microbiology 9 (7), 1683-1694, 2007 | 228 | 2007 |
Influenza-virus-induced signaling cascades: targets for antiviral therapy? S Ludwig, O Planz, S Pleschka, T Wolff Trends in molecular medicine 9 (2), 46-52, 2003 | 227 | 2003 |
A polyphenol rich plant extract, CYSTUS052, exerts anti influenza virus activity in cell culture without toxic side effects or the tendency to induce viral resistance C Ehrhardt, ER Hrincius, V Korte, I Mazur, K Droebner, A Poetter, ... Antiviral research 76 (1), 38-47, 2007 | 225 | 2007 |
Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Cα-mediated activation of ERK signaling H Marjuki, MI Alam, C Ehrhardt, R Wagner, O Planz, HD Klenk, S Ludwig, ... Journal of Biological Chemistry 281 (24), 16707-16715, 2006 | 195 | 2006 |
NF-κB pathway as a potential target for treatment of critical stage COVID-19 patients R Kircheis, E Haasbach, D Lueftenegger, WT Heyken, M Ocker, O Planz Frontiers in immunology 11, 598444, 2020 | 191 | 2020 |
European swine virus as a possible source for the next influenza pandemic? S Ludwig, L Stitz, O Planz, H Van, WM Fitch, C Scholtissek Virology 212 (2), 555-561, 1995 | 184 | 1995 |
MEK inhibition impairs influenza B virus propagation without emergence of resistant variants S Ludwig, T Wolff, C Ehrhardt, WJ Wurzer, J Reinhardt, O Planz, ... FEBS letters 561 (1-3), 37-43, 2004 | 177 | 2004 |
CYSTUS052, a polyphenol-rich plant extract, exerts anti-influenza virus activity in mice K Droebner, C Ehrhardt, A Poetter, S Ludwig, O Planz Antiviral research 76 (1), 1-10, 2007 | 166 | 2007 |
Inhibition of influenza virus-induced NF-kappaB and Raf/MEK/ERK activation can reduce both virus titers and cytokine expression simultaneously in vitro and in vivo R Pinto, S Herold, L Cakarova, K Hoegner, J Lohmeyer, O Planz, ... Antiviral research 92 (1), 45-56, 2011 | 163 | 2011 |
MEK-specific inhibitor U0126 blocks spread of Borna disease virus in cultured cells O Planz, S Pleschka, S Ludwig Journal of Virology 75 (10), 4871-4877, 2001 | 150 | 2001 |
Viral targeting of the interferon-β-inducing Traf family member-associated NF-κB activator (TANK)-binding kinase-1 G Unterstab, S Ludwig, A Anton, O Planz, B Dauber, D Krappmann, ... Proceedings of the National Academy of Sciences 102 (38), 13640-13645, 2005 | 147 | 2005 |