| Interleukin-33 and interferon-γ counter-regulate group 2 innate lymphoid cell activation during immune perturbation AB Molofsky, F Van Gool, HE Liang, SJ Van Dyken, JC Nussbaum, J Lee, ... Immunity 43 (1), 161-174, 2015 | 439 | 2015 |
| Reconstructing eukaryotic NAD metabolism A Rongvaux, F Andris, F Van Gool, O Leo Bioessays 25 (7), 683-690, 2003 | 368 | 2003 |
| Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner F Van Gool, M Galli, C Gueydan, V Kruys, PP Prevot, A Bedalov, ... Nature medicine 15 (2), 206-210, 2009 | 329 | 2009 |
| Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD N Busso, M Karababa, M Nobile, A Rolaz, F Van Gool, M Galli, O Leo, ... PloS one 3 (5), e2267, 2008 | 319 | 2008 |
| Targeted elimination of senescent beta cells prevents type 1 diabetes PJ Thompson, A Shah, V Ntranos, F Van Gool, M Atkinson, A Bhushan Cell metabolism 29 (5), 1045-1060. e10, 2019 | 291 | 2019 |
| Discovery of stimulation-responsive immune enhancers with CRISPR activation DR Simeonov, BG Gowen, M Boontanrart, TL Roth, JD Gagnon, ... Nature 549 (7670), 111-115, 2017 | 291 | 2017 |
| Targeting EZH2 reprograms intratumoral regulatory T cells to enhance cancer immunity D Wang, J Quiros, K Mahuron, CC Pai, V Ranzani, A Young, S Silveria, ... Cell reports 23 (11), 3262-3274, 2018 | 256 | 2018 |
| Nicotinamide phosphoribosyl transferase/pre-B cell colony-enhancing factor/visfatin is required for lymphocyte development and cellular resistance to genotoxic stress A Rongvaux, M Galli, S Denanglaire, F Van Gool, PL Dreze, C Szpirer, ... The Journal of Immunology 181 (7), 4685-4695, 2008 | 231 | 2008 |
| The nicotinamide phosphoribosyltransferase: a molecular link between metabolism, inflammation, and cancer M Gallí, F Van Gool, A Rongvaux, F Andris, O Leo Cancer research 70 (1), 8-11, 2010 | 177 | 2010 |
| CRISPR screen in regulatory T cells reveals modulators of Foxp3 JT Cortez, E Montauti, E Shifrut, J Gatchalian, Y Zhang, O Shaked, Y Xu, ... Nature 582 (7812), 416-420, 2020 | 174 | 2020 |
| Interleukin-5–producing group 2 innate lymphoid cells control eosinophilia induced by interleukin-2 therapy F Van Gool, AB Molofsky, MM Morar, M Rosenzwajg, HE Liang, ... Blood, The Journal of the American Society of Hematology 124 (24), 3572-3576, 2014 | 112 | 2014 |
| ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia B Bondue, O Vosters, P De Nadai, S Glineur, O De Henau, S Luangsay, ... PLoS pathogens 7 (11), e1002358, 2011 | 106 | 2011 |
| The CD28-transmembrane domain mediates chimeric antigen receptor heterodimerization with CD28 YD Muller, DP Nguyen, LMR Ferreira, P Ho, C Raffin, RVB Valencia, ... Frontiers in immunology 12, 639818, 2021 | 91 | 2021 |
| A mutation in the transcription factor Foxp3 drives T helper 2 effector function in regulatory T cells F Van Gool, MLT Nguyen, MR Mumbach, AT Satpathy, WL Rosenthal, ... Immunity 50 (2), 362-377. e6, 2019 | 87 | 2019 |
| Sirtuins and inflammation: friends or foes? M Gallí, F Van Gool, O Leo Biochemical pharmacology 81 (5), 569-576, 2011 | 65 | 2011 |
| Intracellular nicotinamide adenine dinucleotide promotes TNF-induced necroptosis in a sirtuin-dependent manner N Preyat, M Rossi, J Kers, L Chen, J Bertin, PJ Gough, A Le Moine, ... Cell Death & Differentiation 23 (1), 29-40, 2016 | 53 | 2016 |
| Thymically-derived Foxp3+ regulatory T cells are the primary regulators of type 1 diabetes in the non-obese diabetic mouse model DR Holohan, F Van Gool, JA Bluestone PLoS One 14 (10), e0217728, 2019 | 30 | 2019 |
| Nicotinamide inhibits B lymphocyte activation by disrupting MAPK signal transduction J Daniel, Y Marechal, F Van Gool, F Andris, O Leo Biochemical pharmacology 73 (6), 831-842, 2007 | 23 | 2007 |
| Multiple environmental signaling pathways control the differentiation of RORγt-expressing regulatory T cells H Hussein, S Denanglaire, F Van Gool, A Azouz, Y Ajouaou, H El-Khatib, ... Frontiers in Immunology 10, 3007, 2020 | 15 | 2020 |
| The autoimmune targets in IPEX are dominated by gut epithelial proteins D Eriksson, R Bacchetta, HI Gunnarsson, A Chan, F Barzaghi, S Ehl, ... Journal of Allergy and Clinical Immunology 144 (1), 327-330. e8, 2019 | 12 | 2019 |
