Inferring the shape of global epistasis J Otwinowski, DM McCandlish, JB Plotkin Proceedings of the National Academy of Sciences 115 (32), E7550-E7558, 2018 | 206 | 2018 |
Direct observation of colloidal aggregation by critical Casimir forces D Bonn, J Otwinowski, S Sacanna, H Guo, G Wegdam, P Schall Physical review letters 103 (15), 156101, 2009 | 183 | 2009 |
Inferring fitness landscapes by regression produces biased estimates of epistasis J Otwinowski, JB Plotkin Proceedings of the National Academy of Sciences 111 (22), E2301-E2309, 2014 | 93 | 2014 |
Host-pathogen coevolution and the emergence of broadly neutralizing antibodies in chronic infections A Nourmohammad, J Otwinowski, JB Plotkin PLoS genetics 12 (7), e1006171, 2016 | 85 | 2016 |
Biophysical inference of epistasis and the effects of mutations on protein stability and function J Otwinowski Molecular biology and evolution 35 (10), 2345-2354, 2018 | 80 | 2018 |
Genotype to Phenotype Mapping and the Fitness Landscape of the E. coli lac Promoter J Otwinowski, I Nemenman PloS one 8 (5), e61570, 2013 | 66 | 2013 |
Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape NC Wu, J Otwinowski, AJ Thompson, CM Nycholat, A Nourmohammad, ... Nature communications 11 (1), 1233, 2020 | 58 | 2020 |
Dynamics of B cell repertoires and emergence of cross-reactive responses in patients with different severities of COVID-19 Z Montague, H Lv, J Otwinowski, WS DeWitt, G Isacchini, GK Yip, WW Ng, ... Cell Reports 35 (8), 2021 | 44 | 2021 |
Fierce selection and interference in B-cell repertoire response to chronic HIV-1 A Nourmohammad, J Otwinowski, M Łuksza, T Mora, AM Walczak Molecular Biology and Evolution 36 (10), 2184–2194, 2019 | 41 | 2019 |
Novel techniques of laser acceleration: from structures to plasmas S Kalmykov, O Polomarov, D Korobkin, J Otwinowski, J Power, G Shvets Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2006 | 28 | 2006 |
Clonal interference and Mullerʼs ratchet in spatial habitats J Otwinowski, J Krug Physical biology 11 (5), 056003, 2014 | 25 | 2014 |
Design of an optimal combination therapy with broadly neutralizing antibodies to suppress HIV-1 C LaMont, J Otwinowski, K Vanshylla, H Gruell, F Klein, ... Elife 11, e76004, 2022 | 24 | 2022 |
Detecting epistasis from an ensemble of adapting populations DM McCandlish, J Otwinowski, JB Plotkin Evolution 69 (9), 2359-2370, 2015 | 16 | 2015 |
Learning the shape of protein microenvironments with a holographic convolutional neural network MN Pun, A Ivanov, Q Bellamy, Z Montague, C LaMont, P Bradley, ... Proceedings of the National Academy of Sciences 121 (6), e2300838121, 2024 | 12 | 2024 |
Accumulation of beneficial mutations in one dimension J Otwinowski, S Boettcher Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 84 (1 …, 2011 | 10 | 2011 |
A totally asymmetric exclusion process with hierarchical long range connections J Otwinowski, S Boettcher Journal of Statistical Mechanics: Theory and Experiment 2009 (07), P07010, 2009 | 10 | 2009 |
Speeding up evolutionary search by small fitness fluctuations J Otwinowski, S Tanase-Nicola, I Nemenman Journal of statistical physics 144, 367-378, 2011 | 6 | 2011 |
Information-geometric optimization with natural selection J Otwinowski, C LaMont Entropy, 2020 | 3 | 2020 |
Contrastive losses as generalized models of global epistasis DH Brookes, J Otwinowski, S Sinai arXiv preprint arXiv:2305.03136, 2023 | 1 | 2023 |
Learning the shape of the immune and protein universe A Nourmohammad, M Pun, GM Visani, A Ivanov, Q Bellamy, Z Montague, ... Bulletin of the American Physical Society, 2024 | | 2024 |