Modulation of the mitochondrial voltage dependent anion channel (VDAC) by curcumin D Tewari, T Ahmed, VR Chirasani, PK Singh, SK Maji, S Senapati, ... Biochimica Et Biophysica Acta (BBA)-Biomembranes 1848 (1), 151-158, 2015 | 44 | 2015 |
Catestatin Gly364Ser variant alters systemic blood pressure and the risk for hypertension in human populations via endothelial nitric oxide pathway M Kiranmayi, VR Chirasani, PKR Allu, L Subramanian, EE Martelli, ... Hypertension 68 (2), 334-347, 2016 | 39 | 2016 |
Modifications to the framework regions eliminate chimeric antigen receptor tonic signaling E Landoni, G Fucá, J Wang, VR Chirasani, Z Yao, E Dukhovlinova, ... Cancer immunology research 9 (4), 441-453, 2021 | 37 | 2021 |
Regulation of intestinal SGLT1 by catestatin in hyperleptinemic type 2 diabetic mice JA Dominguez Rieg, VR Chirasani, H Koepsell, S Senapati, SK Mahata, ... Laboratory Investigation 96 (1), 98-111, 2016 | 35 | 2016 |
Structural plasticity of cholesteryl ester transfer protein assists the lipid transfer activity VR Chirasani, PD Revanasiddappa, S Senapati Journal of Biological Chemistry 291 (37), 19462-19473, 2016 | 32 | 2016 |
Two-input protein logic gate for computation in living cells YL Vishweshwaraiah, J Chen, VR Chirasani, ED Tabdanov, ... Nature communications 12 (1), 6615, 2021 | 26 | 2021 |
Ca2+-mediated activation of the skeletal-muscle ryanodine receptor ion channel L Xu, VR Chirasani, JS Carter, DA Pasek, NV Dokholyan, N Yamaguchi, ... Journal of Biological Chemistry 293 (50), 19501-19509, 2018 | 25 | 2018 |
Naturally occurring variants of the dysglycemic peptide pancreastatin: differential potencies for multiple cellular functions and structure-function correlation PKR Allu, VR Chirasani, D Ghosh, A Mani, AK Bera, SK Maji, S Senapati, ... Journal of Biological Chemistry 289 (7), 4455-4469, 2014 | 25 | 2014 |
Development of a novel multi-isoform ALDH inhibitor effective as an antimelanoma agent SS Dinavahi, R Gowda, K Gowda, CG Bazewicz, VR Chirasani, MB Battu, ... Molecular cancer therapeutics 19 (2), 447-459, 2020 | 23 | 2020 |
Molecular analyses of novel ASAH1 mutations causing Farber lipogranulomatosis: analyses of exonic splicing enhancer inactivating mutation MD Bashyam, AK Chaudhary, M Kiran, V Reddy, HA Nagarajaram, ... Clinical genetics 86 (6), 530-538, 2014 | 23 | 2014 |
Structural and functional interactions between the Ca2+-, ATP-, and caffeine-binding sites of skeletal muscle ryanodine receptor (RyR1) VR Chirasani, DA Pasek, G Meissner Journal of Biological Chemistry 297 (3), 2021 | 21 | 2021 |
Molecular mechanisms of heterogeneous oligomerization of huntingtin proteins S Bonfanti, MC Lionetti, MR Fumagalli, VR Chirasani, G Tiana, ... Scientific reports 9 (1), 7615, 2019 | 21 | 2019 |
A founder ectodysplasin A receptor (EDAR) mutation results in a high frequency of the autosomal recessive form of hypohidrotic ectodermal dysplasia in India MD Bashyam, AK Chaudhary, EC Reddy, V Reddy, V Acharya, ... British journal of dermatology 166 (4), 819-829, 2012 | 21 | 2012 |
A central core disease mutation in the Ca2+-binding site of skeletal muscle ryanodine receptor impairs single-channel regulation VR Chirasani, L Xu, HG Addis, DA Pasek, NV Dokholyan, G Meissner, ... American Journal of Physiology-Cell Physiology 317 (2), C358-C365, 2019 | 20 | 2019 |
Molecular Basis of Differential Stability and Temperature Sensitivity of ZIKA versus Dengue Virus Protein Shells C Pindi, VR Chirasani, MH Rahman, M Ahsan, PD Revanasiddappa, ... Scientific Reports 10 (1), 8411, 2020 | 19 | 2020 |
Divergent mechanisms activating RAS and small GTPases through post-translational modification N Osaka, Y Hirota, D Ito, Y Ikeda, R Kamata, Y Fujii, VR Chirasani, ... Frontiers in Molecular Biosciences 8, 707439, 2021 | 18 | 2021 |
Limits in Accuracy and a Strategy of RNA Structure Prediction Using Experimental Information J Wang, B Williams, VR Chirasani, A Krokhotin, R Das, ... Nucleic Acids Research 47 (11), 5563–5572, 2019 | 18 | 2019 |
Mechanism of inhibition of cholesteryl ester transfer protein by small molecule inhibitors VR Chirasani, R Sankar, S Senapati The Journal of Physical Chemistry B 120 (33), 8254-8263, 2016 | 17 | 2016 |
Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation BM Murphy, EM Terrell, VR Chirasani, TJ Weiss, RE Lew, ... Nature Communications 13 (1), 3153, 2022 | 16 | 2022 |
Decrease in the generation of amyloid-β due to salvianolic acid B by modulating BACE1 activity S Sundara Kumar Durairajan, V Reddy Chirasani, ... Current Alzheimer Research 14 (11), 1229-1237, 2017 | 16 | 2017 |