Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling P Roswall, M Bocci, M Bartoschek, H Li, G Kristiansen, S Jansson, S Lehn, ... Nature medicine 24 (4), 463-473, 2018 | 159 | 2018 |
Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis ZD Nassar, CY Mah, J Dehairs, IJG Burvenich, S Irani, MM Centenera, ... Elife 9, e54166, 2020 | 119 | 2020 |
Evolution of anti-HER2 therapies for cancer treatment S Parakh, HK Gan, AC Parslow, IJG Burvenich, AW Burgess, AM Scott Cancer treatment reviews 59, 1-21, 2017 | 95 | 2017 |
ELOVL5 is a critical and targetable fatty acid elongase in prostate cancer MM Centenera, JS Scott, J Machiels, ZD Nassar, DC Miller, I Zinonos, ... Cancer research 81 (7), 1704-1718, 2021 | 57 | 2021 |
Bifunctional aptamer–doxorubicin conjugate crosses the blood–brain barrier and selectively delivers its payload to EpCAM-positive tumor cells J Macdonald, D Denoyer, J Henri, A Jamieson, IJG Burvenich, N Pouliot, ... nucleic acid therapeutics 30 (2), 117-128, 2020 | 48 | 2020 |
Molecular imaging of T cell co-regulator factor B7-H3 with 89Zr-DS-5573a IJG Burvenich, S Parakh, FT Lee, N Guo, Z Liu, HK Gan, A Rigopoulos, ... Theranostics 8 (15), 4199, 2018 | 40 | 2018 |
Biodistribution and planar gamma camera imaging of 123I-and 131I-labeled F (ab′) 2 and Fab fragments of monoclonal antibody 14C5 in nude mice bearing an A549 lung tumor IJG Burvenich, S Schoonooghe, P Blanckaert, K Bacher, L Vervoort, ... Nuclear medicine and biology 34 (3), 257-265, 2007 | 38 | 2007 |
In vitro and In vivo targeting properties of iodine-123-or iodine-131–labeled monoclonal antibody 14C5 in a non–small cell lung cancer and colon carcinoma model I Burvenich, S Schoonooghe, B Cornelissen, P Blanckaert, E Coene, ... Clinical cancer research 11 (20), 7288-7296, 2005 | 36 | 2005 |
Smac mimetics LCL161 and GDC-0152 inhibit osteosarcoma growth and metastasis in mice TM Shekhar, IJG Burvenich, MA Harris, A Rigopoulos, D Zanker, ... BMC cancer 19, 1-18, 2019 | 32 | 2019 |
Molecular imaging and quantitation of EphA2 expression in xenograft models with 89Zr-DS-8895a IJG Burvenich, S Parakh, HK Gan, FT Lee, N Guo, A Rigopoulos, ST Lee, ... Journal of Nuclear Medicine 57 (6), 974-980, 2016 | 27 | 2016 |
Monoclonal antibody 14C5 targets integrin αvβ5 I Burvenich, S Schoonooghe, L Vervoort, C Dumolyn, E Coene, ... Molecular Cancer Therapeutics 7 (12), 3771-3779, 2008 | 26 | 2008 |
Synthesis, biodistribution and effects of farnesyltransferase inhibitor therapy on tumour uptake in mice of 99mTc labelled epidermal growth factor B Cornelissen, V Kersemans, I Burvenich, R Oltenfreiter, ... Nuclear medicine communications 26 (2), 147-153, 2005 | 24 | 2005 |
Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008 IJG Burvenich, FT Lee, GA Cartwright, GJ O'Keefe, D Makris, D Cao, ... Clinical Cancer Research 19 (21), 5984-5993, 2013 | 19 | 2013 |
Receptor occupancy imaging studies in oncology drug development IJG Burvenich, S Parakh, AC Parslow, ST Lee, HK Gan, AM Scott The AAPS journal 20, 1-16, 2018 | 18 | 2018 |
Engineering anti-Lewis-Y hu3S193 antibodies with improved therapeutic ratio for radioimmunotherapy of epithelial cancers IJG Burvenich, FT Lee, GJ O’Keefe, D Makris, D Cao, S Gong, ... EJNMMI research 6, 1-13, 2016 | 18 | 2016 |
Preclinical evaluation of monoclonal antibody 14C5 for targeting pancreatic cancer L Vervoort, I Burvenich, S Staelens, C Dumolyn, E Waegemans, ... Cancer Biotherapy and Radiopharmaceuticals 25 (2), 193-205, 2010 | 17 | 2010 |
Novel target selection for nuclear medicine studies ST Lee, I Burvenich, AM Scott Seminars in nuclear medicine 49 (5), 357-368, 2019 | 15 | 2019 |
PH1-derived bivalent bibodies and trivalent tribodies bind differentially to shed and tumour cell-associated MUC1 S Schoonooghe, I Burvenich, L Vervoort, F De Vos, N Mertens, J Grooten Protein Engineering, Design & Selection 23 (9), 721-728, 2010 | 15 | 2010 |
Effect of cyclosporin A administration on the biodistribution and multipinhole μSPECT imaging of [123I]R91150 in rodent brain P Blanckaert, I Burvenich, S Staelens, S De Bruyne, L Moerman, L Wyffels, ... European journal of nuclear medicine and molecular imaging 36, 446-453, 2009 | 15 | 2009 |
Radiolabelling and preclinical characterization of 89Zr-Df-radiolabelled bispecific anti-PD-L1/TGF-βRII fusion protein bintrafusp alfa IJG Burvenich, YW Goh, N Guo, HK Gan, A Rigopoulos, D Cao, Z Liu, ... European journal of nuclear medicine and molecular imaging, 1-14, 2021 | 14 | 2021 |