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| Targeting protein aggregation for the treatment of degenerative diseases YS Eisele, C Monteiro, C Fearns, SE Encalada, RL Wiseman, ET Powers, ... Nature reviews Drug discovery 14 (11), 759-780, 2015 | 423 | 2015 |
| Induction of cerebral β-amyloidosis: intracerebral versus systemic Aβ inoculation YS Eisele, T Bolmont, M Heikenwalder, F Langer, LH Jacobson, ZX Yan, ... Proceedings of the National Academy of Sciences 106 (31), 12926-12931, 2009 | 326 | 2009 |
| Soluble Aβ seeds are potent inducers of cerebral β-amyloid deposition F Langer, YS Eisele, SK Fritschi, M Staufenbiel, LC Walker, M Jucker Journal of Neuroscience 31 (41), 14488-14495, 2011 | 276 | 2011 |
| Seeded strain‐like transmission of β‐amyloid morphotypes in APP transgenic mice G Heilbronner, YS Eisele, F Langer, SA Kaeser, R Novotny, ... EMBO reports 14 (11), 1017-1022, 2013 | 160 | 2013 |
| Blood platelets in the progression of Alzheimer’s disease NS Gowert, L Donner, M Chatterjee, YS Eisele, ST Towhid, P Münzer, ... PloS one 9 (2), e90523, 2014 | 159 | 2014 |
| The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain T Hamaguchi, YS Eisele, NH Varvel, BT Lamb, LC Walker, M Jucker Acta neuropathologica 123, 31-37, 2012 | 114 | 2012 |
| Multiple factors contribute to the peripheral induction of cerebral β-amyloidosis YS Eisele, SK Fritschi, T Hamaguchi, U Obermüller, P Füger, A Skodras, ... Journal of Neuroscience 34 (31), 10264-10273, 2014 | 109 | 2014 |
| A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans A Baranczak, Y Liu, S Connelly, WGH Du, ER Greiner, JC Genereux, ... Journal of the American Chemical Society 137 (23), 7404-7414, 2015 | 104 | 2015 |
| Soluble α-synuclein–antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia D Trudler, KL Nazor, YS Eisele, T Grabauskas, N Dolatabadi, J Parker, ... Proceedings of the National Academy of Sciences 118 (15), e2025847118, 2021 | 92 | 2021 |
| Propagation of Aß pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies YS Eisele, C Duyckaerts Acta neuropathologica 131, 5-25, 2016 | 85 | 2016 |
| α-Synuclein oligomers induce glutamate release from astrocytes and excessive extrasynaptic NMDAR activity in neurons, thus contributing to synapse loss D Trudler, S Sanz-Blasco, YS Eisele, S Ghatak, K Bodhinathan, ... Journal of Neuroscience 41 (10), 2264-2273, 2021 | 75 | 2021 |
| Progression of Seed‐Induced A β Deposition within the Limbic Connectome L Ye, T Hamaguchi, SK Fritschi, YS Eisele, U Obermüller, M Jucker, ... Brain Pathology 25 (6), 743-752, 2015 | 69 | 2015 |
| Persistence of Aβ seeds in APP null mouse brain L Ye, SK Fritschi, J Schelle, U Obermüller, K Degenhardt, SA Kaeser, ... Nature neuroscience 18 (11), 1559-1561, 2015 | 67 | 2015 |
| Gleevec increases levels of the amyloid precursor protein intracellular domain and of the amyloid-β–degrading enzyme neprilysin YS Eisele, M Baumann, B Klebl, C Nordhammer, M Jucker, E Kilger Molecular biology of the cell 18 (9), 3591-3600, 2007 | 64 | 2007 |
| Efficient 1-hour technetium-99 m pyrophosphate imaging protocol for the diagnosis of transthyretin cardiac amyloidosis A Masri, S Bukhari, S Ahmad, R Nieves, YS Eisele, W Follansbee, ... Circulation: Cardiovascular Imaging 13 (2), e010249, 2020 | 63 | 2020 |
| Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients JD Schonhoft, C Monteiro, L Plate, YS Eisele, JM Kelly, D Boland, ... Science translational medicine 9 (407), eaam7621, 2017 | 58 | 2017 |
| Conversion of synthetic Aβ to in vivo active seeds and amyloid plaque formation in a hippocampal slice culture model R Novotny, F Langer, J Mahler, A Skodras, A Vlachos, ... Journal of Neuroscience 36 (18), 5084-5093, 2016 | 57 | 2016 |
| From Soluble A β to Progressive A β Aggregation: Could Prion‐Like Templated Misfolding Play a Role? YS Eisele Brain Pathology 23 (3), 333-341, 2013 | 47 | 2013 |
| Formaldehyde-fixed brain tissue from spontaneously ill α-synuclein transgenic mice induces fatal α-synucleinopathy in transgenic hosts M Schweighauser, M Bacioglu, SK Fritschi, DR Shimshek, PJ Kahle, ... Acta neuropathologica 129, 157-159, 2015 | 38 | 2015 |
