The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy JJ Havel, D Chowell, TA Chan Nature Reviews Cancer 19 (3), 133-150, 2019 | 2002 | 2019 |
Tumor and microenvironment evolution during immunotherapy with nivolumab N Riaz, JJ Havel, V Makarov, A Desrichard, WJ Urba, JS Sims, FS Hodi, ... Cell 171 (4), 934-949. e16, 2017 | 1793 | 2017 |
Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy D Chowell, LGT Morris, CM Grigg, JK Weber, RM Samstein, V Makarov, ... Science 359 (6375), 582-587, 2018 | 1028 | 2018 |
Immunogenic neoantigens derived from gene fusions stimulate T cell responses W Yang, KW Lee, RM Srivastava, F Kuo, C Krishna, D Chowell, ... Nature medicine 25 (5), 767-775, 2019 | 321 | 2019 |
TCR contact residue hydrophobicity is a hallmark of immunogenic CD8+ T cell epitopes D Chowell, S Krishna, PD Becker, C Cocita, J Shu, X Tan, PD Greenberg, ... Proceedings of the National Academy of Sciences 112 (14), E1754-E1762, 2015 | 251 | 2015 |
Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy D Chowell, C Krishna, F Pierini, V Makarov, NA Rizvi, F Kuo, LGT Morris, ... Nature medicine 25 (11), 1715-1720, 2019 | 246 | 2019 |
Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy C Krishna, RG DiNatale, F Kuo, RM Srivastava, L Vuong, D Chowell, ... Cancer Cell 39 (5), 662-677. e6, 2021 | 229 | 2021 |
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity SX Lu, E De Neef, JD Thomas, E Sabio, B Rousseau, M Gigoux, DA Knorr, ... Cell 184 (15), 4032-4047. e31, 2021 | 168 | 2021 |
Improved prediction of immune checkpoint blockade efficacy across multiple cancer types D Chowell, SK Yoo, C Valero, A Pastore, C Krishna, M Lee, D Hoen, ... Nature Biotechnology, 1-8, 2021 | 165 | 2021 |
Tobacco smoking-associated alterations in the immune microenvironment of squamous cell carcinomas A Desrichard, F Kuo, D Chowell, KW Lee, N Riaz, RJ Wong, TA Chan, ... JNCI: Journal of the National Cancer Institute 110 (12), 1386-1392, 2018 | 147 | 2018 |
The immune microenvironment and neoantigen landscape of aggressive salivary gland carcinomas differ by subtype LGT Morris, M Linxweiler, F Kuo, N Katabi, Z Nadeem, MG Dalin, ... Clinical Cancer Research, 2020 | 90 | 2020 |
Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop D Bedognetti, M Ceccarelli, L Galluzzi, R Lu, K Palucka, J Samayoa, ... Journal for immunotherapy of cancer 7 (1), 1-23, 2019 | 81 | 2019 |
HPV16 antibodies as risk factors for oropharyngeal cancer and their association with tumor HPV and smoking status KS Anderson, KR Dahlstrom, JN Cheng, R Alam, G Li, Q Wei, ND Gross, ... Oral oncology 51 (7), 662-667, 2015 | 67 | 2015 |
Modelling the effect of early detection of Ebola D Chowell, C Castillo-Chavez, S Krishna, X Qiu, KS Anderson The Lancet Infectious Diseases 15 (2), 148-149, 2015 | 66 | 2015 |
HPV serum antibodies as predictors of survival and disease progression in patients with HPV-positive squamous cell carcinoma of the oropharynx KR Dahlstrom, KS Anderson, JN Cheng, D Chowell, G Li, M Posner, ... Clinical cancer research 21 (12), 2861-2869, 2015 | 64 | 2015 |
NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer B Salomé, JP Sfakianos, D Ranti, J Daza, C Bieber, A Charap, C Hammer, ... Cancer Cell 40 (9), 1027-1043. e9, 2022 | 62 | 2022 |
Genetic and environmental determinants of human TCR repertoire diversity C Krishna, D Chowell, M Gönen, Y Elhanati, TA Chan Immunity & Ageing 17 (1), 1-7, 2020 | 57 | 2020 |
Modeling the subclonal evolution of cancer cell populations D Chowell, J Napier, R Gupta, KS Anderson, CC Maley, MAW Sayres Cancer research 78 (3), 830-839, 2018 | 53 | 2018 |
Biologic predictors of serologic responses to HPV in oropharyngeal cancer: The HOTSPOT study KS Anderson, JE Gerber, G D’Souza, SI Pai, JN Cheng, R Alam, ... Oral oncology 51 (8), 751-758, 2015 | 50 | 2015 |
Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity X Ma, N Riaz, RM Samstein, M Lee, V Makarov, C Valero, D Chowell, ... Nature Genetics, 1-17, 2022 | 42 | 2022 |