The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth HR Christofk, MG Vander Heiden, MH Harris, A Ramanathan, ... Nature 452 (7184), 230-233, 2008 | 3187 | 2008 |
p63, a p53 homolog at 3q27–29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities A Yang, M Kaghad, Y Wang, E Gillett, MD Fleming, V Dötsch, ... Molecular cell 2 (3), 305-316, 1998 | 2733 | 1998 |
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter A Donovan, A Brownlie, YI Zhou, J Shepard, SJ Pratt, J Moynihan, ... Nature 403 (6771), 776-781, 2000 | 2065 | 2000 |
Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene MD Fleming, CC Trenor III, MA Su, D Foernzler, DR Beier, WF Dietrich, ... Nature genetics 16 (4), 383-386, 1997 | 1432 | 1997 |
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223 JB Johnnidis, MH Harris, RT Wheeler, S Stehling-Sun, MH Lam, O Kirak, ... Nature 451 (7182), 1125-1129, 2008 | 1430 | 2008 |
Recurrent BRAF mutations in Langerhans cell histiocytosis G Badalian-Very, JA Vergilio, BA Degar, LE MacConaill, B Brandner, ... Blood, The Journal of the American Society of Hematology 116 (11), 1919-1923, 2010 | 1258 | 2010 |
Nramp2 is mutated in the anemic Belgrade (b) rat: Evidence of a role for Nramp2 in endosomal iron transport MD Fleming, MA Romano, MA Su, LM Garrick, MD Garrick, NC Andrews Proceedings of the National Academy of Sciences 95 (3), 1148-1153, 1998 | 1177 | 1998 |
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells B Elenbaas, L Spirio, F Koerner, MD Fleming, DB Zimonjic, JL Donaher, ... Genes & development 15 (1), 50-65, 2001 | 1114 | 2001 |
Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease DA Weinstein, CN Roy, MD Fleming, MF Loda, JI Wolfsdorf, NC Andrews Blood, The Journal of the American Society of Hematology 100 (10), 3776-3781, 2002 | 940 | 2002 |
Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells RS Ohgami, DR Campagna, EL Greer, B Antiochos, A McDonald, J Chen, ... Nature genetics 37 (11), 1264-1269, 2005 | 855 | 2005 |
Ineffective erythropoiesis in Stat5a−/−5b−/− mice due to decreased survival of early erythroblasts M Socolovsky, H Nam, MD Fleming, VH Haase, C Brugnara, HF Lodish Blood, The Journal of the American Society of Hematology 98 (12), 3261-3273, 2001 | 833 | 2001 |
Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA) KE Finberg, MM Heeney, DR Campagna, Y Aydınok, HA Pearson, ... Nature genetics 40 (5), 569-571, 2008 | 816 | 2008 |
The Steap proteins are metalloreductases RS Ohgami, DR Campagna, A McDonald, MD Fleming Blood 108 (4), 1388-1394, 2006 | 754 | 2006 |
Telomerase contributes to tumorigenesis by a telomere length-independent mechanism SA Stewart, WC Hahn, BF O'Connor, EN Banner, AS Lundberg, P Modha, ... Proceedings of the National Academy of Sciences 99 (20), 12606-12611, 2002 | 549 | 2002 |
The genomic landscape of pediatric Ewing sarcoma BD Crompton, C Stewart, A Taylor-Weiner, G Alexe, KC Kurek, ... Cancer discovery 4 (11), 1326-1341, 2014 | 515 | 2014 |
Myelopoiesis in the zebrafish, Danio rerio CM Bennett, JP Kanki, J Rhodes, TX Liu, BH Paw, MW Kieran, ... Blood, The Journal of the American Society of Hematology 98 (3), 643-651, 2001 | 513 | 2001 |
Common variants at 10 genomic loci influence hemoglobin A1C levels via glycemic and nonglycemic pathways N Soranzo, S Sanna, E Wheeler, C Gieger, D Radke, J Dupuis, ... Diabetes 59 (12), 3229-3239, 2010 | 485 | 2010 |
Heme‐regulated eIF2α kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency AP Han, C Yu, L Lu, Y Fujiwara, C Browne, G Chin, M Fleming, ... The EMBO journal, 2001 | 484 | 2001 |
A mouse model of juvenile hemochromatosis FW Huang, JL Pinkus, GS Pinkus, MD Fleming, NC Andrews The Journal of clinical investigation 115 (8), 2187-2191, 2005 | 446 | 2005 |
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia MG Kharas, CJ Lengner, F Al-Shahrour, L Bullinger, B Ball, S Zaidi, ... Nature medicine 16 (8), 903-908, 2010 | 421 | 2010 |