| Pharmacokinetic-pharmacodynamic modeling of antibacterial drugs EI Nielsen, LE Friberg Pharmacological reviews 65 (3), 1053-1090, 2013 | 342 | 2013 |
| Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization EI Nielsen, O Cars, LE Friberg Antimicrobial agents and chemotherapy 55 (10), 4619-4630, 2011 | 266 | 2011 |
| Semimechanistic pharmacokinetic/pharmacodynamic model for assessment of activity of antibacterial agents from time-kill curve experiments EI Nielsen, A Viberg, E Löwdin, O Cars, MO Karlsson, M Sandström Antimicrobial agents and chemotherapy 51 (1), 128-136, 2007 | 200 | 2007 |
| From therapeutic drug monitoring to model‐informed precision dosing for antibiotics SG Wicha, AG Märtson, EI Nielsen, BCP Koch, LE Friberg, JW Alffenaar, ... Clinical Pharmacology & Therapeutics 109 (4), 928-941, 2021 | 155 | 2021 |
| The role of infection models and PK/PD modelling for optimising care of critically ill patients with severe infections T Tängdén, V Ramos Martín, TW Felton, EI Nielsen, S Marchand, ... Intensive care medicine 43, 1021-1032, 2017 | 128 | 2017 |
| Pharmacokinetic-pharmacodynamic model for gentamicin and its adaptive resistance with predictions of dosing schedules in newborn infants AF Mohamed, EI Nielsen, O Cars, LE Friberg Antimicrobial agents and chemotherapy 56 (1), 179-188, 2012 | 104 | 2012 |
| Developmental pharmacokinetics of gentamicin in preterm and term neonates: population modelling of a prospective study EI Nielsen, M Sandström, PH Honoré, U Ewald, LE Friberg Clinical pharmacokinetics 48, 253-263, 2009 | 96 | 2009 |
| Levodopa‐entacapone‐carbidopa intestinal gel in Parkinson's disease: A randomized crossover study M Senek, EI Nielsen, D Nyholm Movement Disorders 32 (2), 283-286, 2017 | 95 | 2017 |
| A neonatal amikacin covariate model can be used to predict ontogeny of other drugs eliminated through glomerular filtration in neonates RFW De Cock, K Allegaert, CMT Sherwin, EI Nielsen, M de Hoog, ... Pharmaceutical research 31, 754-767, 2014 | 95 | 2014 |
| Simulation-based evaluation of PK/PD indices for meropenem across patient groups and experimental designs AN Kristoffersson, P David-Pierson, NJ Parrott, O Kuhlmann, T Lave, ... Pharmaceutical research 33, 1115-1125, 2016 | 65 | 2016 |
| Direct analysis of artemisinin in plasma and saliva using coupled-column high-performance liquid chromatography with a restricted-access material pre-column T Gordi, E Nielsen, Z Yu, D Westerlund, M Ashton Journal of Chromatography B: Biomedical Sciences and Applications 742 (1 …, 2000 | 62 | 2000 |
| Population pharmacokinetics of daptomycin in patients affected by severe Gram-positive infections A Di Paolo, C Tascini, M Polillo, G Gemignani, EI Nielsen, G Bocci, ... International journal of antimicrobial agents 42 (3), 250-255, 2013 | 61 | 2013 |
| Semi-mechanistic pharmacokinetic–pharmacodynamic modelling of antibiotic drug combinations MJE Brill, AN Kristoffersson, C Zhao, EI Nielsen, LE Friberg Clinical Microbiology and Infection 24 (7), 697-706, 2018 | 60 | 2018 |
| Handling interoccasion variability in model‐based dose individualization using therapeutic drug monitoring data JA Abrantes, S Jönsson, MO Karlsson, EI Nielsen British journal of clinical pharmacology 85 (6), 1326-1336, 2019 | 58 | 2019 |
| Development and evaluation of a gentamicin pharmacokinetic model that facilitates opportunistic gentamicin therapeutic drug monitoring in neonates and infants E Germovsek, A Kent, T Metsvaht, I Lutsar, N Klein, MA Turner, ... Antimicrobial agents and chemotherapy 60 (8), 4869-4877, 2016 | 54 | 2016 |
| Dynamic interaction of colistin and meropenem on a WT and a resistant strain of Pseudomonas aeruginosa as quantified in a PK/PD model AF Mohamed, AN Kristoffersson, M Karvanen, EI Nielsen, O Cars, ... Journal of Antimicrobial Chemotherapy 71 (5), 1279-1290, 2016 | 54 | 2016 |
| A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants DD Khan, P Lagerbäck, S Cao, U Lustig, EI Nielsen, O Cars, D Hughes, ... Journal of Antimicrobial Chemotherapy 70 (11), 3051-3060, 2015 | 53 | 2015 |
| A whole-body physiologically based pharmacokinetic (WB-PBPK) model of ciprofloxacin: a step towards predicting bacterial killing at sites of infection MW Sadiq, EI Nielsen, D Khachman, JM Conil, B Georges, G Houin, ... Journal of pharmacokinetics and pharmacodynamics 44, 69-79, 2017 | 48 | 2017 |
| Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors J Brem, T Panduwawala, JU Hansen, J Hewitt, E Liepins, P Donets, ... Nature Chemistry 14 (1), 15-24, 2022 | 46 | 2022 |
| Predicting In Vitro Antibacterial Efficacy across Experimental Designs with a Semimechanistic Pharmacokinetic-Pharmacodynamic Model EI Nielsen, O Cars, LE Friberg Antimicrobial agents and chemotherapy 55 (4), 1571-1579, 2011 | 46 | 2011 |
