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Evelyn Lau
Evelyn Lau
Singapore Institute for Clinical Sciences, A*STAR
在 sics.a-star.edu.sg 的电子邮件经过验证
标题
引用次数
引用次数
年份
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression
BP Fairfax, P Humburg, S Makino, V Naranbhai, D Wong, E Lau, L Jostins, ...
Science 343 (6175), 1246949, 2014
8582014
Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling
IM Berenjeno, R Piñeiro, SD Castillo, W Pearce, N McGranahan, ...
Nature communications 8 (1), 1773, 2017
722017
Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele
H Al-Mossawi, N Yager, CA Taylor, E Lau, S Danielli, J de Wit, J Gilchrist, ...
Nature Communications 10 (1), 4575, 2019
512019
Genomic mapping of the MHC transactivator CIITA using an integrated ChIP-seq and genetical genomics approach
D Wong, W Lee, P Humburg, S Makino, E Lau, V Naranbhai, BP Fairfax, ...
Genome biology 15, 1-15, 2014
452014
Genomic response to vitamin D supplementation in the setting of a randomized, placebo-controlled trial
AJ Berlanga-Taylor, K Plant, A Dahl, E Lau, M Hill, D Sims, A Heger, ...
EBioMedicine 31, 133-142, 2018
362018
Natural Killer cells demonstrate distinct eQTL and transcriptome-wide disease associations, highlighting their role in autoimmunity
JJ Gilchrist, S Makino, V Naranbhai, PK Sharma, S Koturan, O Tong, ...
Nature Communications 13 (1), 4073, 2022
202022
Fine-scale genetic structure in the United Arab Emirates reflects endogamous and consanguineous culture, population history, and geography
KS Elliott, M Haber, H Daggag, GB Busby, R Sarwar, D Kennet, ...
Molecular biology and evolution 39 (3), msac039, 2022
142022
Perspective: potential impact and therapeutic implications of oncogenic PI3K activation on chromosomal instability
B Vanhaesebroeck, B Bilanges, RR Madsen, KL Dale, E Lau, ...
Biomolecules 9 (8), 331, 2019
122019
The autoimmune disease risk allele rs6897932 modulates monocyte IL7R surface and soluble receptor levels in a context-specific manner
H Al-Mossawi, E Lau, S Danielli, N Yager, J de Wit, S Makino, J Gilchrist, ...
BiorXiv, 262410, 2018
42018
Context-specific regulation of monocyte surface IL7R expression and soluble receptor secretion by a common autoimmune risk allele
H Al-Mossawi, N Yager, C Taylor, E Lau, S Danielli, J de Wit, J Gilchrist, ...
32018
Effect of vitamin D supplementation on biomarkers of inflammation and immune function: functional genomics analysis of the BEST-D trial
AJ Berlanga-Taylor, K Plant, A Dahl, E Lau, M Hill, D Sims, A Heger, ...
bioRxiv, 217612, 2017
22017
Multi-output prediction of dose–response curves enables drug repositioning and biomarker discovery
JJG Gutierrez, E Lau, S Dharmapalan, M Parker, Y Chen, MA Álvarez, ...
npj Precision Oncology 8 (1), 209, 2024
2024
Genetic determinants of monocyte splicing are enriched for disease susceptibility loci including for COVID-19
B Fairfax, I Nassiri, J Gilchrist, O Tong, E Lau, S Danielli, H Al-Mossawi, ...
2024
Characterization of the genetic determinants of context-specific DNA methylation in primary monocytes
JJ Gilchrist, H Fang, S Danielli, M Tomkova, I Nassiri, E Ng, O Tong, ...
Cell Genomics 4 (5), 2024
2024
Multi-output prediction of dose-response curves enable drug repositioning and biomarker discovery
D Wang, JJG Gutierrez, E Lau, S Dharmapalan, M Parker, Y Chen, ...
2023
Genomic and epigenomic impact of oncogenic mutation in the PIK3CA gene
EKW Lau
UCL (University College London), 2021
2021
GENETIC DETERMINANTS OF TRANSCRIPTIONAL VARIATION IN PRIMARY HUMAN MONOCYTES ACROSS MULTIPLE CONTEXTS
I Nassiri, S Danielli, E Lau, J Gilchrist, H Al-Mossawi, E Mahe, JC Knight, ...
EUROPEAN JOURNAL OF HUMAN GENETICS 27, 1713-1714, 2019
2019
OP0286 Genotypic effects of ankylosing spondylitis associated il7r polymorphisms are mediated through monocytes in inflammation
MH Al-Mossawi, E Lau, S Danielli, N Yager, J De Wit, E Mahe, L Rizvi, ...
Annals of the Rheumatic Diseases 77 (Suppl 2), 191-191, 2018
2018
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