Visualizing sweetness: increasingly diverse applications for fluorescent-tagged glucose bioprobes and their recent structural modifications WH Kim, J Lee, DW Jung, DR Williams Sensors 12 (4), 5005-5027, 2012 | 93 | 2012 |
A unique small molecule inhibitor of enolase clarifies its role in fundamental biological processes DW Jung, WH Kim, SH Park, J Lee, J Kim, D Su, HH Ha, YT Chang, ... ACS chemical biology 8 (6), 1271-1282, 2013 | 88 | 2013 |
Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning B Turanli, C Zhang, W Kim, R Benfeitas, M Uhlen, KY Arga, A Mardinoglu EBioMedicine 42, 386-396, 2019 | 79 | 2019 |
Reprogram or reboot: small molecule approaches for the production of induced pluripotent stem cells and direct cell reprogramming DW Jung, WH Kim, DR Williams ACS Chemical Biology 9 (1), 80-95, 2014 | 75 | 2014 |
Combined metabolic activators accelerates recovery in mild‐to‐moderate COVID‐19 O Altay, M Arif, X Li, H Yang, M Aydın, G Alkurt, W Kim, D Akyol, C Zhang, ... Advanced Science 8 (17), 2101222, 2021 | 72 | 2021 |
Development of a highly visual, simple, and rapid test for the discovery of novel insulin mimetics in living vertebrates J Lee, DW Jung, WH Kim, JI Um, SH Yim, WK Oh, DR Williams ACS Chemical Biology 8 (8), 1803-1814, 2013 | 61 | 2013 |
Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function Z Liu, C Zhang, S Lee, W Kim, M Klevstig, AM Harzandi, N Sikanic, M Arif, ... Metabolic engineering 52, 263-272, 2019 | 48 | 2019 |
ENOblock, a unique small molecule inhibitor of the non-glycolytic functions of enolase, alleviates the symptoms of type 2 diabetes H Cho, JI Um, JH Lee, WH Kim, WS Kang, SH Kim, HH Ha, YC Kim, ... Scientific reports 7 (1), 44186, 2017 | 46 | 2017 |
Natural product derivative BIO promotes recovery after myocardial infarction via unique modulation of the cardiac microenvironment YS Kim, H Jeong, AR Kim, WH Kim, H Cho, JI Um, Y Seo, WS Kang, ... Scientific reports 6 (1), 30726, 2016 | 44 | 2016 |
The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non‐alcoholic fatty liver disease C Zhang, E Bjornson, M Arif, A Tebani, A Lovric, R Benfeitas, M Ozcan, ... Molecular systems biology 16 (4), e9495, 2020 | 37 | 2020 |
Small molecules that recapitulate the early steps of urodele amphibian limb regeneration and confer multipotency WH Kim, DW Jung, J Kim, SH Im, SY Hwang, DR Williams ACS chemical biology 7 (4), 732-743, 2012 | 34 | 2012 |
Chemical targeting of GAPDH moonlighting function in cancer cells reveals its role in tubulin regulation DW Jung, WH Kim, S Seo, E Oh, SH Yim, HH Ha, YT Chang, DR Williams Chemistry & biology 21 (11), 1533-1545, 2014 | 32 | 2014 |
Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients M Zeybel, O Altay, M Arif, X Li, H Yang, C Fredolini, M Akyildiz, B Saglam, ... Molecular systems biology 17 (10), e10459, 2021 | 28 | 2021 |
Chemical genetics and its application to moonlighting in glycolytic enzymes DW Jung, WH Kim, DR Williams Biochemical Society transactions 42 (6), 1756-1761, 2014 | 27 | 2014 |
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning C Zhang, M Shi, W Kim, M Arif, M Klevstig, X Li, H Yang, C Bayram, I Bolat, ... EBioMedicine 83, 2022 | 16 | 2022 |
Isolation and Characterization of Isofraxidin 7‐O‐(6′‐O‐p‐Coumaroyl)‐β‐glucopyranoside from Artemisia capillaris Thunberg: A Novel, Nontoxic … SH Yim, N Tabassum, WH Kim, H Cho, JH Lee, GJ Batkhuu, HJ Kim, ... Evidence‐Based Complementary and Alternative Medicine 2017 (1), 1401279, 2017 | 16 | 2017 |
Prediction of drug candidates for clear cell renal cell carcinoma using a systems biology-based drug repositioning approach X Li, K Shong, W Kim, M Yuan, H Yang, Y Sato, H Kume, S Ogawa, ... EBioMedicine 78, 2022 | 15 | 2022 |
A gene co-expression network-based drug repositioning approach identifies candidates for treatment of hepatocellular carcinoma M Yuan, K Shong, X Li, S Ashraf, M Shi, W Kim, J Nielsen, H Turkez, ... Cancers 14 (6), 1573, 2022 | 15 | 2022 |
Some leopards can change their spots: potential repositioning of stem cell reprogramming compounds as anti-cancer agents WH Kim, H Shen, DW Jung, DR Williams Cell Biology and Toxicology 32, 157-168, 2016 | 15 | 2016 |
Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers X Li, W Kim, M Arif, C Gao, A Hober, D Kotol, L Strandberg, B Forsström, ... Cancers 13 (2), 348, 2021 | 14 | 2021 |