Early functional impairment of sensory-motor connectivity in a mouse model of spinal muscular atrophy GZ Mentis, D Blivis, W Liu, E Drobac, ME Crowder, L Kong, FJ Alvarez, ... Neuron 69 (3), 453-467, 2011 | 396 | 2011 |
ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function A Sharma, AK Lyashchenko, L Lu, SE Nasrabady, M Elmaleh, ... Nature communications 7 (1), 10465, 2016 | 346 | 2016 |
An SMN-dependent U12 splicing event essential for motor circuit function F Lotti, WL Imlach, L Saieva, ES Beck, LT Hao, DK Li, W Jiao, GZ Mentis, ... Cell 151 (2), 440-454, 2012 | 333 | 2012 |
Spinal inhibitory interneuron diversity delineates variant motor microcircuits JB Bikoff, MI Gabitto, AF Rivard, E Drobac, TA Machado, A Miri, ... Cell 165 (1), 207-219, 2016 | 251 | 2016 |
Noncholinergic excitatory actions of motoneurons in the neonatal mammalian spinal cord GZ Mentis, FJ Alvarez, A Bonnot, DS Richards, D Gonzalez-Forero, ... Proceedings of the National Academy of Sciences 102 (20), 277.19, 2005 | 165 | 2005 |
Gain of toxic function by long-term AAV9-mediated SMN overexpression in the sensorimotor circuit M Van Alstyne, I Tattoli, N Delestrée, Y Recinos, E Workman, ... Nature neuroscience 24 (7), 930-940, 2021 | 124 | 2021 |
Reduced gap junctional coupling leads to uncorrelated motor neuron firing and precocious neuromuscular synapse elimination KE Personius, Q Chang, GZ Mentis, MJ O'Donovan, RJ Balice-Gordon Proceedings of the National Academy of Sciences 104 (28), 11808-11813, 2007 | 117 | 2007 |
Reduced sensory synaptic excitation impairs motor neuron function via Kv2. 1 in spinal muscular atrophy EV Fletcher, CM Simon, JG Pagiazitis, JI Chalif, A Vukojicic, E Drobac, ... Nature neuroscience 20 (7), 905-916, 2017 | 113 | 2017 |
Locomotor-like activity generated by the neonatal mouse spinal cord A Bonnot, PJ Whelan, GZ Mentis, MJ O’Donovan Brain research reviews 40 (1-3), 141-151, 2002 | 102 | 2002 |
The classical complement pathway mediates microglia-dependent remodeling of spinal motor circuits during development and in SMA A Vukojicic, N Delestrée, EV Fletcher, JG Pagiazitis, S Sankaranarayanan, ... Cell reports 29 (10), 3087-3100. e7, 2019 | 100 | 2019 |
SMN is essential for the biogenesis of U7 small nuclear ribonucleoprotein and 3′-end formation of histone mRNAs S Tisdale, F Lotti, L Saieva, JP Van Meerbeke, TO Crawford, CJ Sumner, ... Cell reports 5 (5), 1187-1195, 2013 | 99 | 2013 |
Converging mechanisms of p53 activation drive motor neuron degeneration in spinal muscular atrophy CM Simon, Y Dai, M Van Alstyne, C Koutsioumpa, JG Pagiazitis, JI Chalif, ... Cell reports 21 (13), 3767-3780, 2017 | 95 | 2017 |
Dual personality of GABA/glycine-mediated depolarizations in immature spinal cord C Jean-Xavier, GZ Mentis, MJ O'Donovan, D Cattaert, L Vinay Proceedings of the National Academy of Sciences 104 (27), 11477-11482, 2007 | 93 | 2007 |
Motoneurons destined to die are rescued by blocking N-methyl-D-aspartate receptors by MK-801 GZ Mentis, L Greensmith, G Vrbova Neuroscience 54 (2), 283-285, 1993 | 92 | 1993 |
Primary afferent synapses on developing and adult Renshaw cells GZ Mentis, VC Siembab, R Zerda, MJ O'Donovan, FJ Alvarez Journal of Neuroscience 26 (51), 13297-13310, 2006 | 84 | 2006 |
Blockade of N-methyl-D-aspartate receptors by MK-801 (dizocilpine maleate) rescues motoneurones in developing rats L Greensmith, GZ Mentis, G Vrbová Developmental Brain Research 81 (2), 162-170, 1994 | 75 | 1994 |
Target selection of proprioceptive and motor axon synapses on neonatal V1‐derived Ia inhibitory interneurons and Renshaw cells VC Siembab, CA Smith, L Zagoraiou, MC Berrocal, GZ Mentis, FJ Alvarez Journal of Comparative Neurology 518 (23), 4675-4701, 2010 | 74 | 2010 |
Spatiotemporal pattern of motoneuron activation in the rostral lumbar and the sacral segments during locomotor-like activity in the neonatal mouse spinal cord A Bonnot, PJ Whelan, GZ Mentis, MJ O'Donovan The Journal of Neuroscience 22 (3), RC203, 2002 | 73 | 2002 |
Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody S Cantor, W Zhang, N Delestree, L Remedio, GZ Mentis, SJ Burden Elife 7, e34375, 2018 | 70 | 2018 |
Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA L Kong, DO Valdivia, CM Simon, CW Hassinan, N Delestrée, DM Ramos, ... Science translational medicine 13 (578), eabb6871, 2021 | 67 | 2021 |