miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues LR Saunders, AD Sharma, J Tawney, M Nakagawa, K Okita, S Yamanaka, ... Aging (Albany NY) 2 (7), 415, 2010 | 267 | 2010 |
MicroRNAs control hepatocyte proliferation during liver regeneration G Song, AD Sharma, GR Roll, R Ng, AY Lee, RH Blelloch, NM Frandsen, ... Hepatology 51 (5), 1735-1743, 2010 | 249 | 2010 |
Direct reprogramming of hepatic myofibroblasts into hepatocytes in vivo attenuates liver fibrosis G Song, M Pacher, A Balakrishnan, Q Yuan, HC Tsay, D Yang, J Reetz, ... Cell stem cell 18 (6), 797-808, 2016 | 204 | 2016 |
MicroRNA‐221 overexpression accelerates hepatocyte proliferation during liver regeneration Q Yuan, K Loya, B Rani, S Möbus, A Balakrishnan, J Lamle, T Cathomen, ... Hepatology 57 (1), 299-310, 2013 | 180 | 2013 |
Reevaluation of bone marrow-derived cells as a source for hepatocyte regeneration T Cantz, AD Sharma, A Jochheim-Richter, L Arseniev, C Klein, MP Manns, ... Cell transplantation 13 (6), 659-666, 2004 | 157 | 2004 |
MicroRNA-342-3p is a potent tumour suppressor in hepatocellular carcinoma RM Komoll, Q Hu, O Olarewaju, L von Döhlen, Q Yuan, Y Xie, HC Tsay, ... Journal of Hepatology 74 (1), 122-134, 2021 | 143 | 2021 |
Human cord blood stem cells generate human cytokeratin 18-negative hepatocyte-like cells in injured mouse liver AD Sharma, T Cantz, R Richter, K Eckert, R Henschler, L Wilkens, ... The American journal of pathology 167 (2), 555-564, 2005 | 118 | 2005 |
Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model T Yang, M Poenisch, R Khanal, Q Hu, Z Dai, R Li, G Song, Q Yuan, Q Yao, ... Journal of hepatology 75 (6), 1420-1433, 2021 | 105 | 2021 |
The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice LE Buitrago‐Molina, S Marhenke, T Longerich, AD Sharma, AE Boukouris, ... Hepatology 58 (3), 1143-1152, 2013 | 100 | 2013 |
MicroRNA‐221 regulates FAS‐induced fulminant liver failure AD Sharma, N Narain, EM Händel, M Iken, N Singhal, T Cathomen, ... Hepatology 53 (5), 1651-1661, 2011 | 93 | 2011 |
Innovations, challenges, and minimal information for standardization of humanized mice R Stripecke, C Münz, JJ Schuringa, KD Bissig, B Soper, T Meeham, ... EMBO molecular medicine 12 (7), e8662, 2020 | 90 | 2020 |
Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis H Willenbring, AD Sharma, A Vogel, AY Lee, A Rothfuss, Z Wang, ... Cancer cell 14 (1), 59-67, 2008 | 82 | 2008 |
Small molecules facilitate single factor-mediated hepatic reprogramming KT Lim, SC Lee, Y Gao, KP Kim, G Song, SY An, K Adachi, YJ Jang, J Kim, ... Cell reports 15 (4), 814-829, 2016 | 75 | 2016 |
A screen in mice uncovers repression of lipoprotein lipase by microRNA‐29a as a mechanism for lipid distribution away from the liver AN Mattis, G Song, K Hitchner, RY Kim, AY Lee, AD Sharma, Y Malato, ... Hepatology 61 (1), 141-152, 2015 | 63 | 2015 |
Generation of healthy mice from gene-corrected disease-specific induced pluripotent stem cells G Wu, N Liu, I Rittelmeyer, AD Sharma, M Sgodda, H Zaehres, ... PLoS Biology 9 (7), e1001099, 2011 | 62 | 2011 |
Murine embryonic stem cell-derived hepatic progenitor cells engraft in recipient livers with limited capacity of liver tissue formation AD Sharma, T Cantz, A Vogel, A Schambach, D Haridass, M Iken, ... Cell Transplantation 17 (3), 313-323, 2008 | 62 | 2008 |
MicroRNA-125b-5p mimic inhibits acute liver failure D Yang, Q Yuan, A Balakrishnan, H Bantel, JH Klusmann, MP Manns, ... Nature communications 7 (1), 11916, 2016 | 61 | 2016 |
Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells Z Dai, G Song, A Balakrishnan, T Yang, Q Yuan, S Möbus, AC Weiss, ... Gut 69 (6), 1104-1115, 2020 | 56 | 2020 |
Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosis HC Tsay, Q Yuan, A Balakrishnan, M Kaiser, S Möbus, E Kozdrowska, ... Journal of Hepatology 70 (4), 722-734, 2019 | 53 | 2019 |
The role of stem cells in physiology, pathophysiology, and therapy of the liver AD Sharma, T Cantz, MP Manns, M Ott Stem Cell Reviews 2, 51-58, 2006 | 52 | 2006 |