Highly efficient synthesis of covalently cross‐linked peptide helices by ring‐closing metathesis HE Blackwell, RH Grubbs Angewandte Chemie International Edition 37 (23), 3281-3284, 1998 | 730 | 1998 |
Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening CM Grozinger, ED Chao, HE Blackwell, D Moazed, SL Schreiber Journal of Biological Chemistry 276 (42), 38837-38843, 2001 | 683 | 2001 |
Application of ring-closing metathesis to the synthesis of rigidified amino acids and peptides SJ Miller, HE Blackwell, RH Grubbs Journal of the American Chemical Society 118 (40), 9606-9614, 1996 | 657 | 1996 |
New approaches to olefin cross-metathesis HE Blackwell, DJ O'Leary, AK Chatterjee, RA Washenfelder, ... Journal of the American Chemical Society 122 (1), 58-71, 2000 | 496 | 2000 |
Small molecule inhibitors of bacterial quorum sensing and biofilm formation GD Geske, RJ Wezeman, AP Siegel, HE Blackwell Journal of the American Chemical Society 127 (37), 12762-12763, 2005 | 420 | 2005 |
Structure–function relationships in peptoids: recent advances toward deciphering the structural requirements for biological function SA Fowler, HE Blackwell Organic & biomolecular chemistry 7 (8), 1508-1524, 2009 | 344 | 2009 |
Modulation of Bacterial Quorum Sensing with Synthetic Ligands: Systematic Evaluation of N-Acylated Homoserine Lactones in Multiple Species and New Insights … GD Geske, JC O'Neill, DM Miller, ME Mattmann, HE Blackwell Journal of the American Chemical Society 129 (44), 13613-13625, 2007 | 313 | 2007 |
Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria GD Geske, JC O’Neill, HE Blackwell Chemical Society Reviews 37 (7), 1432-1447, 2008 | 290 | 2008 |
Ring-closing metathesis of olefinic peptides: design, synthesis, and structural characterization of macrocyclic helical peptides HE Blackwell, JD Sadowsky, RJ Howard, JN Sampson, JA Chao, ... The Journal of organic chemistry 66 (16), 5291-5302, 2001 | 282 | 2001 |
Self-assembly of taper-shaped monoesters of oligo (ethylene oxide) with 3, 4, 5-tris (p-dodecyloxybenzyloxy) benzoic acid and of their polymethacrylates into tubular … V Percec, J Heck, D Tomazos, F Falkenberg, H Blackwell, G Ungar Journal of the Chemical Society, Perkin Transactions 1, 2799-2811, 1993 | 237 | 1993 |
Local and tunable n→ π* interactions regulate amide isomerism in the peptoid backbone BC Gorske, BL Bastian, GD Geske, HE Blackwell Journal of the American Chemical Society 129 (29), 8928-8929, 2007 | 227 | 2007 |
Extraordinarily Robust Polyproline Type I Peptoid Helices Generated via the Incorporation of α-Chiral Aromatic N-1-Naphthylethyl Side Chains JR Stringer, JA Crapster, IA Guzei, HE Blackwell Journal of the American Chemical Society 133 (39), 15559-15567, 2011 | 216 | 2011 |
New strategies for the design of folded peptoids revealed by a survey of noncovalent interactions in model systems BC Gorske, JR Stringer, BL Bastian, SA Fowler, HE Blackwell Journal of the American Chemical Society 131 (45), 16555-16567, 2009 | 207 | 2009 |
Out of the oil bath and into the oven—Microwave-assisted combinatorial chemistry heats up HE Blackwell Organic & biomolecular chemistry 1 (8), 1251-1255, 2003 | 205 | 2003 |
Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform DR Spring, S Krishnan, HE Blackwell, SL Schreiber Journal of the American Chemical Society 124 (7), 1354-1363, 2002 | 200 | 2002 |
SIR1, an upstream component in auxin signaling identified by chemical genetics Y Zhao, X Dai, HE Blackwell, SL Schreiber, J Chory Science 301 (5636), 1107-1110, 2003 | 199 | 2003 |
Small Molecule Disruption of Quorum Sensing Cross-Regulation in Pseudomonas aeruginosa Causes Major and Unexpected Alterations to Virulence Phenotypes MA Welsh, NR Eibergen, JD Moore, HE Blackwell Journal of the American Chemical Society 137 (4), 1510-1519, 2015 | 185 | 2015 |
Chemical genetic approaches to plant biology HE Blackwell, Y Zhao Plant Physiology 133 (2), 448-455, 2003 | 182 | 2003 |
Synthesis of conformationally restricted amino acids, peptides, and peptidomimetics by catalytic ring closing metathesis RH Grubbs, SJ Miller, HE Blackwell US Patent 5,811,515, 1998 | 181 | 1998 |
2-Aminobenzimidazole derivatives strongly inhibit and disperse Pseudomonas aeruginosa biofilms R Frei, AS Breitbach, HE Blackwell Angewandte Chemie (International ed. in English) 51 (21), 5226, 2012 | 164 | 2012 |