TET and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming X Hu, L Zhang, SQ Mao, Z Li, J Chen, RR Zhang, HP Wu, J Gao, F Guo, ... Cell stem cell 14 (4), 512-522, 2014 | 365 | 2014 |
TET-mediated DNA demethylation controls gastrulation by regulating Lefty–Nodal signalling HQ Dai, BA Wang, L Yang, JJ Chen, GC Zhu, ML Sun, H Ge, R Wang, ... Nature 538 (7626), 528, 2016 | 202 | 2016 |
CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning S Jain, Z Ba, Y Zhang, HQ Dai, FW Alt Cell 174 (1), 102-116, 2018 | 104 | 2018 |
CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning Z Ba, J Lou, AY Ye, HQ Dai, EW Dring, SG Lin, S Jain, N Kyritsis, ... Nature, 2020 | 87 | 2020 |
Loop Extrusion Mediates Physiological Igh Locus Contraction For RAG Scanning HQ Dai, H Hu, J Lou, AY Ye, Z Ba, X Zhang, Y Zhang, L Zhao, HS Yoon, ... Nature 590, 338–343, 2021 | 79 | 2021 |
The role of chromatin loop extrusion in antibody diversification Y Zhang, X Zhang, HQ Dai, H Hu, FW Alt Nature Reviews Immunology 22 (9), 550-566, 2022 | 61 | 2022 |
Neural blastocyst complementation enables mouse forebrain organogenesis AN Chang, Z Liang, HQ Dai, AM Chapdelaine-Williams, N Andrews, ... Nature 563, 126–130, 2018 | 50 | 2018 |
An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion S Luo, J Zhang, AJB Kreutzberger, A Eaton, RJ Edwards, C Jing, HQ Dai, ... Science immunology 7 (76), eadd5446, 2022 | 43 | 2022 |
TET enzymes regulate skeletal development through increasing chromatin accessibility of RUNX2 target genes L Wang, X You, D Ruan, R Shao, HQ Dai, W Shen, GL Xu, W Liu, W Zou Nature communications 13 (1), 4709, 2022 | 24 | 2022 |
Contribution of the IGCR1 regulatory element and the 3′Igh CTCF-binding elements to regulation of Igh V(D)J recombination Z Liang, L Zhao, AY Ye, SG Lin, Y Zhang, C Guo, HQ Dai, Z Ba, FW Alt Proceedings of the National Academy of Sciences 120 (26), e2306564120, 2023 | 9 | 2023 |
Direct analysis of brain phenotypes via neural blastocyst complementation HQ Dai, Z Liang, AN Chang, AM Chapdelaine-Williams, B Alvarado, ... Nature Protocols 15, 3154–3181, 2020 | 7 | 2020 |
Humanized antibody potently neutralizes all SARS-CoV-2 variants by a novel mechanism S Luo, J Zhang, AJB Kreutzberger, A Eaton, RJ Edwards, C Jing, HQ Dai, ... bioRxiv, 2022.06. 26.497634, 2022 | 3 | 2022 |
CRISPR/Cas9-mediated genome editing in mouse embryonic stem cells and direct analysis of brain phenotypes via neural blastocyst complementation B Schwer, FW Alt, AN Chang, Z Liang, HQ Dai, AM Chapdelaine-Williams | 2 | 2018 |
Mesoscale sequence feature modulates AID activity in antibody diversification: Mesoscale DNA feature facilitates SHM J Li, HQ Dai Acta Biochimica et Biophysica Sinica 55 (9), 1515, 2023 | | 2023 |
Contribution of the IGCR1 regulatory element and the 3’Igh CBEs to Regulation of Igh V(D)J Recombination Z Liang, L Zhao, A Yongxin Ye, SG Lin, Y Zhang, C Guo, HQ Dai, Z Ba, ... bioRxiv, 2023.04. 21.537836, 2023 | | 2023 |
Loop Extrusion Mediates Physiological Locus Contraction for V(D)J Recombination HQ Dai, H Hu, J Lou, AY Ye, AM Chapdelaine-Williams, N Kyritsis, ... bioRxiv, 2020 | | 2020 |