The repertoire of mutational signatures in human cancer LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AWT Ng, Y Wu, A Boot, ... Nature 578 (7793), 94-101, 2020 | 2706 | 2020 |
Pan-cancer analysis of whole genomes. S Hirano, L Yang, M Juul, CA Purdie, BP O'Neill, R Kabbe, ... Nature 578 (DKFZ-2020-01051), 82-93, 2020 | 1781* | 2020 |
Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ... Cancer Discovery 7 (10), 1116-1135, 2017 | 755 | 2017 |
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia AWT Ng, SL Poon, MN Huang, JQ Lim, A Boot, W Yu, Y Suzuki, ... Science translational medicine 9 (412), eaan6446, 2017 | 347 | 2017 |
In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors A Boot, MN Huang, AWT Ng, SC Ho, JQ Lim, Y Kawakami, K Chayama, ... Genome research 28 (5), 654-665, 2018 | 154 | 2018 |
Global epidemiology and genetics of hepatocellular carcinoma MR Toh, EYT Wong, SH Wong, AWT Ng, LH Loo, PKH Chow, J Ngeow Gastroenterology 164 (5), 766-782, 2023 | 136 | 2023 |
Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors MN Huang, W Yu, WW Teoh, M Ardin, A Jusakul, AWT Ng, A Boot, ... Genome research 27 (9), 1475-1486, 2017 | 116 | 2017 |
Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans M Zhivagui, AWT Ng, M Ardin, MI Churchwell, M Pandey, C Renard, ... Genome research 29 (4), 521-531, 2019 | 78 | 2019 |
Epigenomic Promoter Alterations Amplify Gene Isoform and Immunogenic Diversity in Gastric Adenocarcinoma A Qamra, M Xing, N Padmanabhan, JJT Kwok, S Zhang, C Xu, YS Leong, ... Cancer Discovery 7 (6), 630-651, 2017 | 51 | 2017 |
Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types A Boot, AWT Ng, FT Chong, SC Ho, W Yu, DSW Tan, NG Iyer, SG Rozen Genome research 30 (6), 803-813, 2020 | 47 | 2020 |
Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus J Luebeck, AWT Ng, PC Galipeau, X Li, CA Sanchez, ... Nature, 1-8, 2023 | 46 | 2023 |
The Drosophila Dicer-1 Partner Loquacious Enhances miRNA Processing from Hairpins with Unstable Structures at the Dicing Site MYT Lim, AWT Ng, Y Chou, TP Lim, A Simcox, G Tucker-Kellogg, ... Cell reports 15 (8), 1795-1808, 2016 | 25 | 2016 |
Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer YC Tang, SC Ho, E Tan, AWT Ng, JR McPherson, GYL Goh, BT Teh, ... Breast Cancer Research 20 (1), 22, 2018 | 22 | 2018 |
Serial circulating tumor DNA detection using a personalized, tumor-informed assay in esophageal adenocarcinoma patients following resection E Ococks, S Sharma, AWT Ng, A Aleshin, RC Fitzgerald, E Smyth Gastroenterology 161 (5), 1705-1708. e2, 2021 | 12 | 2021 |
Rearrangement processes and structural variations show evidence of selection in oesophageal adenocarcinomas AWT Ng, G Contino, S Killcoyne, G Devonshire, R Hsu, S Abbas, J Su, ... Communications Biology 5 (1), 1-12, 2022 | 9 | 2022 |
Accuracy of mutational signature software on correlated signatures Y Wu, EHZ Chua, AWT Ng, A Boot, SG Rozen Scientific reports 12 (1), 1-12, 2022 | 8 | 2022 |
Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett’s oesophagus surveillance: individual-level data analysis EL Black, E Ococks, G Devonshire, AWT Ng, M O’Donovan, S Malhotra, ... Gut, 2023 | 5 | 2023 |
DNA epigenetic signature predictive of benefit from neoadjuvant chemotherapy in oesophageal adenocarcinoma: results from the MRC OE02 trial R Sundar, A Ng, H Zouridis, N Padmanabhan, T Sheng, S Zhang, MH Lee, ... European Journal of Cancer 123, 48-57, 2019 | 5 | 2019 |
Mutational processes in cancer preferentially affect binding of particular transcription factors M Liu, A Boot, AWT Ng, R Gordân, SG Rozen Scientific reports 11 (1), 1-12, 2021 | 3 | 2021 |
Disentangling oncogenic amplicons in esophageal adenocarcinoma AWT Ng, DP McClurg, B Wesley, SA Zamani, E Black, A Miremadi, ... Nature Communications 15 (1), 4074, 2024 | | 2024 |