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Mandy (Mengdie) Wang
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A solvatochromic fluorescent probe reveals polarity heterogeneity upon protein aggregation in cells
W Wan, L Zeng, W Jin, X Chen, D Shen, Y Huang, M Wang, Y Bai, H Lyu, ...
Angewandte Chemie 133 (49), 26069-26075, 2021
662021
Rational Design of Crystallization‐Induced‐Emission Probes To Detect Amorphous Protein Aggregation in Live Cells
D Shen, W Jin, Y Bai, Y Huang, H Lyu, L Zeng, M Wang, Y Tang, W Wan, ...
Angewandte Chemie 133 (29), 16203-16212, 2021
572021
Covalent probes for aggregated protein imaging via michael addition
W Wan, Y Huang, Q Xia, Y Bai, Y Chen, W Jin, M Wang, D Shen, H Lyu, ...
Angewandte Chemie International Edition 60 (20), 11335-11343, 2021
372021
Derivatizing Nile Red fluorophores to quantify the heterogeneous polarity upon protein aggregation in the cell
R Sun, W Wan, W Jin, Y Bai, Q Xia, M Wang, Y Huang, L Zeng, J Sun, ...
Chemical Communications 58 (35), 5407-5410, 2022
152022
Common pitfalls and recommendations for using a turbidity assay to study protein phase separation
Y Huang, Y Bai, W Jin, D Shen, H Lyu, L Zeng, M Wang, Y Liu
Biochemistry 60 (32), 2447-2456, 2021
132021
Covalent Solvatochromic Proteome Stress Sensor Based on the Schiff Base Reaction
D Shen, W Jin, Q Zhao, M Wang, B Zhang, H Feng, W Wan, Y Bai, H Lyu, ...
Analytical Chemistry 94 (41), 14143-14150, 2022
122022
Solvatochromic cellular stress sensors reveal the compactness heterogeneity and dynamics of aggregated proteome
Q Xia, W Wan, W Jin, Y Huang, R Sun, M Wang, B Jing, C Peng, X Dong, ...
ACS sensors 7 (7), 1919-1925, 2022
122022
Interrogating the impact of aggregation‐induced emission nanoparticles on in vitro protein stability, ex vivo protein homeostasis, and in vivo biocompatibility: Special Issue …
W Wan, Q Zhao, B Jing, C Peng, M Wang, Y Huang, W Jin, B Zhong, ...
Aggregate 3 (6), e274, 2022
92022
A novel virus detection strategy enabled by TR512-peptide-based bioorthogonal capture and enrichment of preamplified nucleic acid
M Zhu, C Huangfu, W Wan, M Wang, H Lv, X Zhang, F Wang, H Zhi, ...
Analytical Chemistry 94 (14), 5591-5598, 2022
92022
Developing an Affinity-Based Chemical Proteomics Method to In Situ Capture Amorphous Aggregated Proteome and Profile Its Heterogeneity in Stressed Cells
D Shen, Q Zhao, M Wang, B Zhong, W Jin, Y Huang, H Jin, B Jing, W Wan, ...
Analytical Chemistry 95 (15), 6358-6366, 2023
82023
Identification of a novel transthyretin mutation D39Y in a cardiac amyloidosis patient and its biochemical characterizations
Q Ma, M Wang, Y Huang, Y Nie, X Zhang, DD Yang, Z Wang, S Ding, ...
Frontiers in Cardiovascular Medicine 10, 1091183, 2023
52023
Clinical and biochemical characterization of hereditary transthyretin amyloidosis caused by E61K mutation
X Chu, M Wang, R Tang, Y Huang, J Yu, Y Cao, Y Zheng, Z Xie, J Deng, ...
Frontiers in Molecular Neuroscience 15, 1003303, 2022
52022
Plastic nanoparticles cause proteome stress and aggregation by compromising cellular protein homeostasis ex vivo and in vivo
B Jing, W Wan, B Hu, W Jin, Z Zhang, C Peng, M Wang, J Deng, X Dong, ...
Ecotoxicology and Environmental Safety 262, 115347, 2023
42023
Biochemical and biophysical properties of an unreported T96R mutation causing transthyretin cardiac amyloidosis
M Jiang, M Wang, Z Tao, Y Chai, Q Liu, Q Lu, Q Wu, X Ying, Y Huang, ...
Amyloid 30 (2), 188-198, 2023
42023
Tailoring the Amphiphilicity of Fluorescent Protein Chromophores to Detect Intracellular Proteome Aggregation in Diverse Biological Samples
M Wang, Z Zhang, B Jing, X Dong, K Guo, J Deng, Z Wang, W Wan, W Jin, ...
Analytical Chemistry 95 (31), 11751-11760, 2023
22023
Time-Resolved Ultraviolet Photodissociation Mass Spectrometry Probes the Mutation-Induced Alterations in Protein Stability and Unfolding Dynamics
P Luo, Z Liu, C Lai, Z Jin, M Wang, H Zhao, Y Liu, W Zhang, X Wang, ...
Journal of the American Chemical Society 146 (13), 8832-8838, 2024
12024
Unraveling Intracellular Protein Corona Components of Nanoplastics via Photocatalytic Protein Proximity Labeling
Z Zhang, X Dong, W Wan, H Guo, R Sun, H Feng, M Wang, Z Wang, H Jin, ...
Analytical Chemistry 96 (12), 4978-4986, 2024
12024
An ultra performance liquid chromatography method for transthyretin variants screening and heart failure assisting diagnosis
S Wang, L Guan, Y Sun, L Cui, S Guo, M Wang, Y Liu, X Cui, F Zhao, ...
Clinica Chimica Acta 553, 117709, 2024
12024
Integrated imaging and proteomics sensors detect proteome aggregation induced by platinum-based chemotherapy drugs in living cells and mice model
J Deng, W Wan, M Wang, R Sun, W Jin, D Shen, Q Xia, Z Zhang, X Dong, ...
Sensors and Actuators B: Chemical 413, 135891, 2024
2024
Characterization of Transthyretin Mutation G47V Associated with Hereditary Cardiac Amyloidosis
X He, M Wang, J Sun, Z Yu, X Hu, Y Liu, X Lin
Cardiology 149 (4), 383-395, 2024
2024
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