| E3 ligase ligands in successful PROTACs: an overview of syntheses and linker attachment points A Bricelj, C Steinebach, R Kuchta, M Gütschow, I Sosič Frontiers in chemistry 9, 707317, 2021 | 122 | 2021 |
| Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F M Hrast, I Sosič, R Šink, S Gobec Bioorganic chemistry 55, 2-15, 2014 | 114 | 2014 |
| Structural characterization and biological evaluation of a clioquinol–ruthenium complex with copper-independent antileukaemic activity M Gobec, J Kljun, I Sosič, I Mlinarič-Raščan, M Uršič, S Gobec, I Turel Dalton Transactions 43 (24), 9045-9051, 2014 | 106 | 2014 |
| Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds B Mirković, M Renko, S Turk, I Sosič, Z Jevnikar, N Obermajer, D Turk, ... ChemMedChem 6 (8), 1351, 2011 | 102 | 2011 |
| Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders C Steinebach, YLD Ng, I Sosič, CS Lee, S Chen, S Lindner, LP Vu, ... Chemical science 11 (13), 3474-3486, 2020 | 98 | 2020 |
| Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure–activity relationships of nitroxoline derivatives I Sosič, B Mirkovic, K Arenz, B Stefane, J Kos, S Gobec Journal of Medicinal Chemistry 56 (2), 521-533, 2013 | 84 | 2013 |
| Antibacterial and β‐lactamase inhibitory activity of monocyclic β‐Lactams L Decuyper, M Jukič, I Sosič, A Žula, M D'hooghe, S Gobec Medicinal Research Reviews 38 (2), 426-503, 2018 | 80 | 2018 |
| Design, synthesis, and evaluation of new thiadiazole-based direct inhibitors of enoyl acyl carrier protein reductase (InhA) for the treatment of tuberculosis R Sink, I Sosic, M Zivec, R Fernandez-Menendez, S Turk, S Pajk, ... Journal of medicinal chemistry 58 (2), 613-624, 2015 | 77 | 2015 |
| Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity B Mirković, B Markelc, M Butinar, A Mitrović, I Sosič, S Gobec, O Vasiljeva, ... Oncotarget 6 (22), 19027, 2015 | 70 | 2015 |
| E3 ligase ligand chemistries: from building blocks to protein degraders I Sosič, A Bricelj, C Steinebach Chemical Society Reviews 51 (9), 3487-3534, 2022 | 64 | 2022 |
| A new ‘golden age’for the antitubercular target InhA K Rožman, I Sosič, R Fernandez, RJ Young, A Mendoza, S Gobec, ... Drug discovery today 22 (3), 492-502, 2017 | 63 | 2017 |
| Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents D Knez, B Brus, N Coquelle, I Sosič, R Šink, X Brazzolotto, J Mravljak, ... Bioorganic & Medicinal Chemistry 23 (15), 4442-4452, 2015 | 62 | 2015 |
| Structure–activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF M Hrast, S Turk, I Sosič, D Knez, CP Randall, H Barreteau, ... European Journal of medicinal chemistry 66, 32-45, 2013 | 58 | 2013 |
| Nonpeptidic selective inhibitors of the chymotrypsin‐like (β5 i) subunit of the immunoproteasome I Sosič, M Gobec, B Brus, D Knez, M Živec, J Konc, S Lešnik, M Ogrizek, ... Angewandte Chemie International Edition 55 (19), 5745-5748, 2016 | 57 | 2016 |
| A MedChem toolbox for cereblon-directed PROTACs C Steinebach, I Sosič, S Lindner, A Bricelj, F Kohl, YLD Ng, M Monschke, ... MedChemComm 10 (6), 1037-1041, 2019 | 56 | 2019 |
| New noncovalent inhibitors of penicillin-binding proteins from penicillin-resistant bacteria S Turk, O Verlaine, T Gerards, M Živec, J Humljan, I Sosič, A Amoroso, ... Plos one 6 (5), e19418, 2011 | 53 | 2011 |
| Synthesis of aminoboronic acid derivatives: an update on recent advances A Šterman, I Sosič, S Gobec, Z Časar Organic Chemistry Frontiers 6 (16), 2991-2998, 2019 | 50 | 2019 |
| Clioquinol–ruthenium complex impairs tumour cell invasion by inhibiting cathepsin B activity A Mitrović, J Kljun, I Sosič, S Gobec, I Turel, J Kos Dalton Transactions 45 (42), 16913-16921, 2016 | 50 | 2016 |
| 4,6-Substituted-1,3,5-triazin-2(1H)-ones as monocyclic catalytic inhibitors of human DNA topoisomerase IIα targeting the ATP binding site B Pogorelčnik, M Janežič, I Sosič, S Gobec, T Solmajer, A Perdih Bioorganic & medicinal chemistry 23 (15), 4218-4229, 2015 | 45 | 2015 |
| New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold S Pajk, M Živec, R Šink, I Sosič, M Neu, C Chung, M Martínez-Hoyos, ... European Journal of Medicinal Chemistry 112, 252-257, 2016 | 43 | 2016 |
