| Small-molecule inhibition of human immunodeficiency virus type 1 replication by targeting the interaction between Vif and ElonginC T Zuo, D Liu, W Lv, X Wang, J Wang, M Lv, W Huang, J Wu, H Zhang, ... Journal of virology 86 (10), 5497-5507, 2012 | 88 | 2012 |
| Synthesis of Mixed (E,Z)-, (E)-, and (Z)-Norendoxifen with Dual Aromatase Inhibitory and Estrogen Receptor Modulatory Activities W Lv, J Liu, D Lu, DA Flockhart, M Cushman Journal of medicinal chemistry 56 (11), 4611-4618, 2013 | 72 | 2013 |
| Discovery of potent indenoisoquinoline topoisomerase I poisons lacking the 3-nitro toxicophore DE Beck, M Abdelmalak, W Lv, PVN Reddy, GS Tender, E O’Neill, ... Journal of medicinal chemistry 58 (9), 3997-4015, 2015 | 58 | 2015 |
| DUPA conjugation of a cytotoxic indenoisoquinoline topoisomerase I inhibitor for selective prostate cancer cell targeting J Roy, TX Nguyen, AK Kanduluru, C Venkatesh, W Lv, PVN Reddy, ... Journal of medicinal chemistry 58 (7), 3094-3103, 2015 | 58 | 2015 |
| Recent developments using small molecules to target RAD51: how to best modulate RAD51 for anticancer therapy? B Budke, W Lv, AP Kozikowski, PP Connell ChemMedChem 11 (22), 2468-2473, 2016 | 51 | 2016 |
| Development of small molecules that specifically inhibit the D-loop activity of RAD51 W Lv, B Budke, M Pawlowski, PP Connell, AP Kozikowski Journal of medicinal chemistry 59 (10), 4511-4525, 2016 | 51 | 2016 |
| Investigation of the structure–activity relationships of aza-A-ring indenoisoquinoline topoisomerase I poisons DE Beck, PVN Reddy, W Lv, M Abdelmalak, GS Tender, S Lopez, ... Journal of medicinal chemistry 59 (8), 3840-3853, 2016 | 48 | 2016 |
| Design and synthesis of norendoxifen analogues with dual aromatase inhibitory and estrogen receptor modulatory activities W Lv, J Liu, TC Skaar, DA Flockhart, M Cushman Journal of medicinal chemistry 58 (6), 2623-2648, 2015 | 48 | 2015 |
| Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents J Cheng, PM Giguère, OK Onajole, W Lv, A Gaisin, H Gunosewoyo, ... Journal of medicinal chemistry 58 (4), 1992-2002, 2015 | 43 | 2015 |
| Three-dimensional structure of HIV-1 VIF constructed by comparative modeling and the function characterization analyzed by molecular dynamics simulation W Lv, Z Liu, H Jin, X Yu, L Zhang, L Zhang Organic & biomolecular chemistry 5 (4), 617-626, 2007 | 42 | 2007 |
| Synthesis and biological evaluation of new fluorinated and chlorinated indenoisoquinoline topoisomerase I poisons DE Beck, W Lv, M Abdelmalak, CB Plescia, K Agama, C Marchand, ... Bioorganic & medicinal chemistry 24 (7), 1469-1479, 2016 | 40 | 2016 |
| Copper ions inhibit S-adenosylhomocysteine hydrolase by causing dissociation of NAD+ cofactor M Li, Y Li, J Chen, W Wei, X Pan, J Liu, Q Liu, W Leu, L Zhang, X Yang, ... Biochemistry 46 (41), 11451-11458, 2007 | 40 | 2007 |
| Synthesis of 3-(3-aryl-pyrrolidin-1-yl)-5-aryl-1, 2, 4-triazines that have antibacterial activity and also inhibit inorganic pyrophosphatase W Lv, B Banerjee, KL Molland, MN Seleem, A Ghafoor, MI Hamed, B Wan, ... Bioorganic & medicinal chemistry 22 (1), 406-418, 2014 | 38 | 2014 |
| In Vitro Evaluation of Potential Bitterness-Masking Terpenoids from the Canada Goldenrod (Solidago canadensis) J Li, L Pan, JN Fletcher, W Lv, Y Deng, MA Vincent, JP Slack, ... Journal of Natural Products 77 (7), 1739-1743, 2014 | 37 | 2014 |
| Design and synthesis of mercaptoacetamides as potent, selective, and brain permeable histone deacetylase 6 inhibitors W Lv, G Zhang, C Barinka, JH Eubanks, AP Kozikowski ACS Medicinal Chemistry Letters 8 (5), 510-515, 2017 | 36 | 2017 |
| Synthesis and antibacterial activity of 9-oxime ether non-ketolides, and novel binding mode of alkylides with bacterial rRNA JH Liang, W Lv, XL Li, K An, M Cushman, H Wang, YC Xu Bioorganic & medicinal chemistry letters 23 (5), 1387-1393, 2013 | 30 | 2013 |
| Synthesis of triphenylethylene bisphenols as aromatase inhibitors that also modulate estrogen receptors W Lv, J Liu, TC Skaar, E O’Neill, G Yu, DA Flockhart, M Cushman Journal of medicinal chemistry 59 (1), 157-170, 2016 | 29 | 2016 |
| Synthesis, antibacterial activity and docking of 14-membered 9-O-(3-arylalkyl) oxime 11, 12-cyclic carbonate ketolides JH Liang, K An, W Lv, M Cushman, H Wang, YC Xu European Journal of Medicinal Chemistry 59, 54-63, 2013 | 24 | 2013 |
| Inhibition of Cytochrome P450 Enzymes by the E-and Z-Isomers of Norendoxifen J Liu, PJ Flockhart, D Lu, W Lv, WJ Lu, X Han, M Cushman, DA Flockhart Drug Metabolism and Disposition 41 (9), 1715-1720, 2013 | 21 | 2013 |
| A new Suzuki synthesis of triphenylethylenes that inhibit aromatase and bind to estrogen receptors α and β LM Zhao, HS Jin, J Liu, TC Skaar, J Ipe, W Lv, DA Flockhart, M Cushman Bioorganic & medicinal chemistry 24 (21), 5400-5409, 2016 | 20 | 2016 |
