IRE1 signaling exacerbates Alzheimer’s disease pathogenesis C Duran-Aniotz, VH Cornejo, S Espinoza, ÁO Ardiles, DB Medinas, ... Acta neuropathologica 134, 489-506, 2017 | 199 | 2017 |
Regulation of memory formation by the transcription factor XBP1 G Martínez, RL Vidal, P Mardones, FG Serrano, AO Ardiles, C Wirth, ... Cell reports 14 (6), 1382-1394, 2016 | 173 | 2016 |
Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer’s disease AO Ardiles, CC Tapia-Rojas, M Mandal, F Alexandre, A Kirkwood, ... Proceedings of the National Academy of Sciences 109 (34), 13835-13840, 2012 | 154 | 2012 |
Pull-push neuromodulation of LTP and LTD enables bidirectional experience-induced synaptic scaling in visual cortex SY Huang, M Trevino, K He, A Ardiles, R de Pasquale, Y Guo, A Palacios, ... Neuron 73 (3), 497-510, 2012 | 152 | 2012 |
Alzheimer's disease in the human eye. Clinical tests that identify ocular and visual information processing deficit as biomarkers LYL Chang, J Lowe, A Ardiles, J Lim, AC Grey, K Robertson, ... Alzheimer's & Dementia 10 (2), 251-261, 2014 | 121 | 2014 |
Pannexin 1 regulates bidirectional hippocampal synaptic plasticity in adult mice AO Ardiles, C Flores-Muñoz, G Toro-Ayala, AM Cárdenas, AG Palacios, ... Frontiers in cellular neuroscience 8, 326, 2014 | 95 | 2014 |
Metabotropic glutamate receptors induce a form of LTP controlled by translation and arc signaling in the hippocampus H Wang, AO Ardiles, S Yang, T Tran, R Posada-Duque, G Valdivia, ... Journal of Neuroscience 36 (5), 1723-1729, 2016 | 87 | 2016 |
Role of tau protein in neuronal damage in Alzheimer's disease and Down syndrome AM Cárdenas, AO Ardiles, N Barraza, X Baéz-Matus, P Caviedes Archives of medical research 43 (8), 645-654, 2012 | 83 | 2012 |
The elusive crypt olfactory receptor neuron: evidence for its stimulation by amino acids and cAMP pathway agonists A Vielma, A Ardiles, L Delgado, O Schmachtenberg Journal of Experimental Biology 211 (15), 2417-2422, 2008 | 61 | 2008 |
Alzheimer’s Disease-Related Protein Expression in the Retina of Octodon degus LY Du, LYL Chang, AO Ardiles, C Tapia-Rojas, J Araya, NC Inestrosa, ... PLoS one 10 (8), e0135499, 2015 | 53 | 2015 |
Octodon degus (Molina 1782): a model in comparative biology and biomedicine AO Ardiles, J Ewer, ML Acosta, A Kirkwood, AD Martinez, LA Ebensperger, ... Cold Spring Harbor Protocols 2013 (4), pdb. emo071357, 2013 | 50 | 2013 |
Lack of pannexin 1 alters synaptic GluN2 subunit composition and spatial reversal learning in mice I Gajardo, CS Salazar, D Lopez-Espíndola, C Estay, C Flores-Muñoz, ... Frontiers in Molecular Neuroscience 11, 114, 2018 | 49 | 2018 |
Age Progression of Neuropathological Markers in the Brain of the Chilean Rodent Octodon degus, a Natural Model of Alzheimer's Disease NC Inestrosa, JA Ríos, P Cisternas, C Tapia‐Rojas, DS Rivera, N Braidy, ... Brain Pathology 25 (6), 679-691, 2015 | 45 | 2015 |
Genetic variants associated with neurodegenerative Alzheimer disease in natural models C Salazar, G Valdivia, ÁO Ardiles, J Ewer, AG Palacios Biological Research 49, 1-9, 2016 | 38 | 2016 |
Integrity of mGluR-LTD in the associative/commissural inputs to CA3 correlates with successful aging in rats S Yang, A Megill, AO Ardiles, S Ransom, T Tran, MT Koh, HK Lee, ... Journal of Neuroscience 33 (31), 12670-12678, 2013 | 30 | 2013 |
Acute pannexin 1 blockade mitigates early synaptic plasticity defects in a mouse model of Alzheimer’s disease C Flores-Muñoz, B Gómez, E Mery, P Mujica, I Gajardo, C Córdova, ... Frontiers in Cellular Neuroscience 14, 46, 2020 | 28 | 2020 |
Molecular and cellular mechanisms of synaptopathies AO Ardiles, AM Grabrucker, FG Scholl, G Rudenko, T Borsello Neural plasticity 2017, 2017 | 24 | 2017 |
Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging F Cabral‐Miranda, G Tamburini, G Martinez, AO Ardiles, DB Medinas, ... The EMBO Journal 41 (22), e111952, 2022 | 23 | 2022 |
Evidence of synaptic and neurochemical remodeling in the retina of aging degus LYL Chang, AO Ardiles, C Tapia-Rojas, J Araya, NC Inestrosa, ... Frontiers in Neuroscience 14, 161, 2020 | 21 | 2020 |
Inhibition of DNA methylation impairs synaptic plasticity during an early time window in rats P Muñoz, C Estay, P Díaz, C Elgueta, ÁO Ardiles, PA Lizana Neural Plasticity 2016 (1), 4783836, 2016 | 21 | 2016 |