The chemotactic action of urokinase on smooth muscle cells is dependent on its kringle domain: characterization of interactions and contribution to chemotaxis S Mukhina, V Stepanova, D Traktouev, A Poliakov, R Beabealashvilly, ... Journal of Biological Chemistry 275 (22), 16450-16458, 2000 | 148 | 2000 |
Urokinase-induced mitogenesis is mediated by casein kinase 2 and nucleolin I Dumler, V Stepanova, U Jerke, OA Mayboroda, F Vogel, P Bouvet, ... Current Biology 9 (24), 1468-1476, 1999 | 125 | 1999 |
Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation S Zaitsev, D Spitzer, JC Murciano, BS Ding, S Tliba, MA Kowalska, ... Blood, The Journal of the American Society of Hematology 115 (25), 5241-5248, 2010 | 122 | 2010 |
Urokinase as a multidomain protein and polyfunctional cell regulator VV Stepanova, VA Tkachuk Biochemistry (Moscow) 67, 109-118, 2002 | 112 | 2002 |
Nuclear translocation of urokinase-type plasminogen activator V Stepanova, T Lebedeva, A Kuo, S Yarovoi, S Tkachuk, S Zaitsev, ... Blood, The Journal of the American Society of Hematology 112 (1), 100-110, 2008 | 99 | 2008 |
Regulation and role of urokinase plasminogen activator in vascular remodelling V Tkachuk, V Stepanova, PJ Little, A Bobik Clinical and experimental pharmacology and physiology 23 (9), 759-765, 1996 | 96 | 1996 |
Folliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK EA Goncharova, DA Goncharov, ML James, EN Atochina-Vasserman, ... Cell reports 7 (2), 412-423, 2014 | 95 | 2014 |
Activation of p38 MAP-kinase and caldesmon phosphorylation are essential for urokinase-induced human smooth muscle cell migration EA Goncharova, AV Vorotnikov, EO Gracheva, CLA Wang, ... Walter de Gruyter 383 (1), 115-126, 2002 | 88 | 2002 |
Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer S Asuthkar, V Stepanova, T Lebedeva, AXL Holterman, N Estes, ... Molecular biology of the cell 24 (17), 2620-2632, 2013 | 85 | 2013 |
Urokinase gene transfer augments angiogenesis in ischemic skeletal and myocardial muscle DO Traktuev, ZI Tsokolaeva, AA Shevelev, KA Talitskiy, VV Stepanova, ... Molecular Therapy 15 (11), 1939-1946, 2007 | 84 | 2007 |
Urokinase-type plasminogen activator (uPA) promotes angiogenesis by attenuating proline-rich homeodomain protein (PRH) transcription factor activity and de-repressing vascular … V Stepanova, PS Jayaraman, SV Zaitsev, T Lebedeva, K Bdeir, ... Journal of Biological Chemistry 291 (29), 15029-15045, 2016 | 83 | 2016 |
Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia DB Cines, SV Yarovoi, SV Zaitsev, T Lebedeva, L Rauova, M Poncz, ... Blood advances 1 (1), 62-74, 2016 | 74 | 2016 |
Urokinase plasminogen activator induces human smooth muscle cell migration and proliferation via distinct receptor-dependent and proteolysis-dependent mechanisms V Stepanova, S Mukhina, E Köhler, TJ Resink, P Erne, VA Tkachuk Molecular and cellular biochemistry 195, 199-206, 1999 | 69 | 1999 |
Targeting of a mutant plasminogen activator to circulating red blood cells for prophylactic fibrinolysis S Zaitsev, D Spitzer, JC Murciano, BS Ding, S Tliba, MA Kowalska, ... Journal of Pharmacology and Experimental Therapeutics 332 (3), 1022-1031, 2010 | 67 | 2010 |
Neutrophil α-defensins promote thrombosis in vivo by altering fibrin formation, structure, and stability R Abu-Fanne, V Stepanova, RI Litvinov, S Abdeen, K Bdeir, M Higazi, ... Blood, The Journal of the American Society of Hematology 133 (5), 481-493, 2019 | 64 | 2019 |
Urokinase plasminogen activator augments cell proliferation and neointima formation in injured arteries via proteolytic mechanisms O Plekhanova, Y Parfyonova, R Bibilashvily, S Domogatskii, V Stepanova, ... Atherosclerosis 159 (2), 297-306, 2001 | 60 | 2001 |
Urokinase-dependent human vascular smooth muscle cell adhesion requires selective vitronectin phosphorylation by ectoprotein kinase CK2 V Stepanova, U Jerke, V Sagach, C Lindschau, R Dietz, H Haller, ... Journal of Biological Chemistry 277 (12), 10265-10272, 2002 | 57 | 2002 |
Urokinase plasminogen activator enhances neointima growth and reduces lumen size in injured carotid arteries OS Plekhanova, YV Parfyonova, RS Bibilashvily, VV Stepanova, P Erne, ... Journal of hypertension 18 (8), 1065-1069, 2000 | 50 | 2000 |
Urokinase plasminogen activator induces smooth muscle cell migration: key role of growth factor-like domain V Stepanova, A Bobik, R Bibilashvily, A Belogurov, I Rybalkin, ... FEBS letters 414 (2), 471-474, 1997 | 49 | 1997 |
Urokinase induces matrix metalloproteinase-9/gelatinase B expression in THP-1 monocytes via ERK1/2 and cytosolic phospholipase A2 activation and eicosanoid production M Menshikov, N Torosyan, E Elizarova, K Plakida, A Vorotnikov, ... Journal of vascular research 43 (5), 482-490, 2006 | 40 | 2006 |