Genomic, pathway network, and immunologic features distinguishing squamous carcinomas JD Campbell, C Yau, R Bowlby, Y Liu, K Brennan, H Fan, AM Taylor, ... Cell reports 23 (1), 194-212. e6, 2018 | 305 | 2018 |
Intragenic ATM methylation in peripheral blood DNA as a biomarker of breast cancer risk K Brennan, M Garcia-Closas, N Orr, O Fletcher, M Jones, A Ashworth, ... Cancer research 72 (9), 2304-2313, 2012 | 176 | 2012 |
Is there a link between genome-wide hypomethylation in blood and cancer risk? K Brennan, JM Flanagan Cancer prevention research 5 (12), 1345-1357, 2012 | 125 | 2012 |
Development and validation of radiomic signatures of head and neck squamous cell carcinoma molecular features and subtypes C Huang, M Cintra, K Brennan, M Zhou, AD Colevas, N Fischbein, S Zhu, ... EBioMedicine 45, 70-80, 2019 | 88 | 2019 |
MethylMix 2.0: an R package for identifying DNA methylation genes PL Cedoz, M Prunello, K Brennan, O Gevaert Bioinformatics 34 (17), 3044-3046, 2018 | 81 | 2018 |
NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma K Brennan, JH Shin, JK Tay, M Prunello, AJ Gentles, JB Sunwoo, ... Scientific reports 7 (1), 17064, 2017 | 81 | 2017 |
Identification of an atypical etiological head and neck squamous carcinoma subtype featuring the CpG island methylator phenotype K Brennan, JL Koenig, AJ Gentles, JB Sunwoo, O Gevaert EBioMedicine 17, 223-236, 2017 | 66 | 2017 |
Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer AS Perry, G O'Hurley, OA Raheem, K Brennan, S Wong, A O'Grady, ... International journal of cancer 132 (8), 1771-1780, 2013 | 60 | 2013 |
Module analysis captures pancancer genetically and epigenetically deregulated cancer driver genes for smoking and antiviral response M Champion, K Brennan, T Croonenborghs, AJ Gentles, N Pochet, ... EBioMedicine 27, 156-166, 2018 | 50 | 2018 |
A systematic review of studies of DNA methylation in the context of a weight loss intervention L Aronica, AJ Levine, K Brennan, J Mi, C Gardner, RW Haile, MP Hitchins Epigenomics 9 (5), 769-787, 2017 | 50 | 2017 |
Methylome analysis and epigenetic changes associated with menarcheal age CA Demetriou, J Chen, S Polidoro, K Van Veldhoven, C Cuenin, ... PLoS One 8 (11), e79391, 2013 | 50 | 2013 |
Expression of GBGT1 is epigenetically regulated by DNA methylation in ovarian cancer cells F Jacob, MP Hitchins, A Fedier, K Brennan, S Nixdorf, NF Hacker, R Ward, ... BMC molecular biology 15, 1-13, 2014 | 49 | 2014 |
Benchmark of long non-coding RNA quantification for RNA sequencing of cancer samples H Zheng, K Brennan, M Hernaez, O Gevaert Gigascience 8 (12), giz145, 2019 | 42 | 2019 |
Development of prognostic signatures for intermediate-risk papillary thyroid cancer K Brennan, C Holsinger, C Dosiou, JB Sunwoo, H Akatsu, R Haile, ... BMC cancer 16, 1-12, 2016 | 28 | 2016 |
Epigenetic epidemiology for cancer risk: harnessing germline epigenetic variation K Brennan, JM Flanagan Cancer Epigenetics: Methods and Protocols, 439-465, 2012 | 26 | 2012 |
Docetaxel maintains its cytotoxic activity under hypoxic conditions in prostate cancer cells JC Forde, AS Perry, K Brennan, LM Martin, MP Lawler, TH Lynch, ... Urologic Oncology: Seminars and Original Investigations 30 (6), 912-919, 2012 | 20 | 2012 |
NSD1 mutations deregulate transcription and DNA methylation of bivalent developmental genes in Sotos syndrome K Brennan, H Zheng, JA Fahrner, JH Shin, AJ Gentles, B Schaefer, ... Human molecular genetics 31 (13), 2164-2184, 2022 | 17 | 2022 |
The impact of DNA methylation on the cancer proteome MM Magzoub, M Prunello, K Brennan, O Gevaert PLOS Computational Biology 15 (7), e1007245, 2019 | 17 | 2019 |
Methylated SEPTIN9 plasma test for colorectal cancer detection may be applicable to Lynch syndrome MP Hitchins, IP Vogelaar, K Brennan, S Haraldsdottir, N Zhou, B Martin, ... BMJ Open Gastroenterology 6 (1), e000299, 2019 | 14 | 2019 |
Development of a DNA Methylation–Based Diagnostic Signature to Distinguish Benign Oncocytoma From Renal Cell Carcinoma K Brennan, TJ Metzner, CS Kao, CE Massie, GD Stewart, RW Haile, ... JCO Precision Oncology 4, 1141-1151, 2020 | 11 | 2020 |