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Alexandra Schäfer
Alexandra Schäfer
在 email.unc.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
TP Sheahan, AC Sims, SR Leist, A Schäfer, J Won, AJ Brown, ...
Nature communications 11 (1), 1-14, 2020
21602020
SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract
YJ Hou, K Okuda, CE Edwards, DR Martinez, T Asakura, KH Dinnon, ...
Cell 182 (2), 429-446. e14, 2020
15042020
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness
KS Corbett, DK Edwards, SR Leist, OM Abiona, S Boyoglu-Barnum, ...
Nature 586 (7830), 567-571, 2020
14732020
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
TP Sheahan, AC Sims, S Zhou, RL Graham, AJ Pruijssers, ML Agostini, ...
Science translational medicine 12 (541), eabb5883, 2020
10892020
Potently neutralizing and protective human antibodies against SARS-CoV-2
SJ Zost, P Gilchuk, JB Case, E Binshtein, RE Chen, JP Nkolola, A Schäfer, ...
Nature 584 (7821), 443-449, 2020
10802020
SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo
YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda, KH Dinnon III, SR Leist, ...
Science 370 (6523), 1464-1468, 2020
9552020
Epstein–Barr virus microRNAs are evolutionarily conserved and differentially expressed
X Cai, A Schäfer, S Lu, JP Bilello, RC Desrosiers, R Edwards, ...
PLoS pathogens 2 (3), e23, 2006
7042006
A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures
KH Dinnon III, SR Leist, A Schäfer, CE Edwards, DR Martinez, ...
Nature 586 (7830), 560-566, 2020
6652020
A single-dose intranasal ChAd vaccine protects upper and lower respiratory tracts against SARS-CoV-2
AO Hassan, NM Kafai, IP Dmitriev, JM Fox, BK Smith, IB Harvey, RE Chen, ...
Cell 183 (1), 169-184. e13, 2020
5112020
A mouse-adapted SARS-CoV-2 induces acute lung injury and mortality in standard laboratory mice
SR Leist, KH Dinnon, A Schäfer, VT Longping, K Okuda, YJ Hou, A West, ...
Cell 183 (4), 1070-1085. e12, 2020
5052020
Remdesivir inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice
AJ Pruijssers, AS George, A Schäfer, SR Leist, LE Gralinksi, KH Dinnon, ...
Cell reports 32 (3), 2020
4942020
Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2
AC Walls, B Fiala, A Schäfer, S Wrenn, MN Pham, M Murphy, ...
Cell 183 (5), 1367-1382. e17, 2020
4532020
Toll-like receptor 3 signaling via TRIF contributes to a protective innate immune response to severe acute respiratory syndrome coronavirus infection
AL Totura, A Whitmore, S Agnihothram, A Schäfer, MG Katze, MT Heise, ...
MBio 6 (3), 10.1128/mbio. 00638-15, 2015
4242015
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801
A Wahl, LE Gralinski, CE Johnson, W Yao, M Kovarova, KH Dinnon III, ...
Nature 591 (7850), 451-457, 2021
3902021
Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo
A Schäfer, F Muecksch, JCC Lorenzi, SR Leist, M Cipolla, S Bournazos, ...
Journal of Experimental Medicine 218 (3), e20201993, 2020
3102020
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies
D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer, SM Alam, K Wiehe, ...
Cell 184 (16), 4203-4219. e32, 2021
297*2021
Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor
A Schäfer, HP Bogerd, BR Cullen
Virology 328 (2), 163-168, 2004
2862004
Human APOBEC3B is a potent inhibitor of HIV-1 infectivity and is resistant to HIV-1 Vif
BP Doehle, A Schäfer, BR Cullen
Virology 339 (2), 281-288, 2005
2772005
Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses
VD Menachery, AJ Eisfeld, A Schäfer, L Josset, AC Sims, S Proll, S Fan, ...
MBio 5 (3), 10.1128/mbio. 01174-14, 2014
2652014
Foamy virus Bet proteins function as novel inhibitors of the APOBEC3 family of innate antiretroviral defense factors
RA Russell, HL Wiegand, MD Moore, A Schäfer, MO McClure, ...
Journal of virology 79 (14), 8724-8731, 2005
2272005
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