Impaired adult neurogenesis is an early event in Alzheimer’s disease neurodegeneration, mediated by intracellular Aβ oligomers C Scopa, F Marrocco, V Latina, F Ruggeri, V Corvaglia, F La Regina, ... Cell Death & Differentiation 27 (3), 934-948, 2020 | 130 | 2020 |
NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease V Corsetti, F Florenzano, A Atlante, A Bobba, MT Ciotti, F Natale, ... Human molecular genetics 24 (11), 3058-3081, 2015 | 130 | 2015 |
A NH 2 tau fragment targets neuronal mitochondria at AD synapses: possible implications for neurodegeneration G Amadoro, V Corsetti, A Stringaro, M Colone, S D'Aguanno, G Meli, ... Journal of Alzheimer's Disease 21 (2), 445-470, 2010 | 111 | 2010 |
Activation of the amyloidogenic route by NGF deprivation induces apoptotic death in PC12 cells C Matrone, A Di Luzio, G Meli, S D'Aguanno, C Severini, MT Ciotti, ... Journal of Alzheimer's Disease 13 (1), 81-96, 2008 | 107 | 2008 |
Direct in vivo intracellular selection of conformation-sensitive antibody domains targeting Alzheimer's amyloid-β oligomers G Meli, M Visintin, I Cannistraci, A Cattaneo Journal of molecular biology 387 (3), 584-606, 2009 | 96 | 2009 |
NGF steers microglia toward a neuroprotective phenotype C Rizzi, A Tiberi, M Giustizieri, MC Marrone, F Gobbo, NM Carucci, G Meli, ... Glia 66 (7), 1395-1416, 2018 | 95 | 2018 |
ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice C Tiveron, L Fasulo, S Capsoni, F Malerba, S Marinelli, F Paoletti, ... Cell Death & Differentiation 20 (8), 1017-1030, 2013 | 88 | 2013 |
Intranasal “painless” human nerve growth factors slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice S Capsoni, S Marinelli, M Ceci, D Vignone, G Amato, F Malerba, F Paoletti, ... PloS one 7 (5), e37555, 2012 | 85 | 2012 |
Intracellular antibodies for proteomics M Visintin, GA Meli, I Cannistraci, A Cattaneo Journal of immunological methods 290 (1-2), 135-153, 2004 | 73 | 2004 |
Retinal pathological features and proteome signatures of Alzheimer’s disease Y Koronyo, A Rentsendorj, N Mirzaei, GC Regis, J Sheyn, H Shi, E Barron, ... Acta Neuropathologica 145 (4), 409-438, 2023 | 72 | 2023 |
Conformational targeting of intracellular Aβ oligomers demonstrates their pathological oligomerization inside the endoplasmic reticulum G Meli, A Lecci, A Manca, N Krako, V Albertini, L Benussi, R Ghidoni, ... Nature communications 5 (1), 3867, 2014 | 62 | 2014 |
Amyloid Β-peptide increases mitochondria-endoplasmic reticulum contact altering mitochondrial function and autophagosome formation in Alzheimer’s disease-related models NS Leal, G Dentoni, B Schreiner, L Naia, A Piras, C Graff, A Cattaneo, ... Cells 9 (12), 2552, 2020 | 48 | 2020 |
The chemokine CXCL12 mediates the anti-amyloidogenic action of painless human nerve growth factor S Capsoni, F Malerba, NM Carucci, C Rizzi, C Criscuolo, N Origlia, ... Brain 140 (1), 201-217, 2017 | 48 | 2017 |
Diabetic patients and retinal proliferation: an evaluation of the role of vascular endothelial growth factor (VEGF) VG Nicoletti, R Nicoletti, N Ferrara, G Meli, M Reibaldi, A Reibaldi Experimental and clinical endocrinology & diabetes 111 (04), 209-214, 2003 | 42 | 2003 |
Characterization of mitochondrial dysfunction in the 7PA2 cell model of Alzheimer's disease N Krako, MC Magnifico, M Arese, G Meli, E Forte, A Lecci, A Manca, ... Journal of Alzheimer's Disease 37 (4), 747-758, 2013 | 38 | 2013 |
The development of ADAM10 endocytosis inhibitors for the treatment of Alzheimer’s disease S Musardo, S Therin, S Pelucchi, L D’Andrea, R Stringhi, A Ribeiro, ... Molecular Therapy 30 (7), 2474-2490, 2022 | 23 | 2022 |
Activity-induced amyloid-β oligomers drive compensatory synaptic rearrangements in brain circuits controlling memory of presymptomatic Alzheimer's disease mice A Pignataro, G Meli, R Pagano, V Fontebasso, R Battistella, G Conforto, ... Biological Psychiatry 86 (3), 185-195, 2019 | 19 | 2019 |
Intrabodies for protein interference in Alzheimer’s disease G Meli, N Krako, A Manca, A Lecci, A Cattaneo J. Biol. Regul. Homeost. Agents 27, 89-105, 2013 | 5 | 2013 |
Computational modeling of inhibitory transsynaptic signaling in hippocampal and cortical neurons expressing intrabodies against gephyrin CA Lupascu, A Morabito, F Ruggeri, C Parisi, D Pimpinella, R Pizzarelli, ... Frontiers in Cellular Neuroscience 14, 173, 2020 | 2 | 2020 |
P4–323: Intracellularly selected recombinant antibodies targeting beta–amyloid oligomers G Meli, M Visintin, I Cannistraci, D Avossa, A Westlind-Danielsson, ... Alzheimer's & Dementia 2, S612-S612, 2006 | 2 | 2006 |