Caspases: keys in the ignition of cell death JB Denault, GS Salvesen Chemical reviews 102 (12), 4489-4500, 2002 | 539 | 2002 |
XIAP inhibits caspase‐3 and‐7 using two binding sites: evolutionarily conserved mechanism of IAPs FL Scott, JB Denault, SJ Riedl, H Shin, M Renatus, GS Salvesen The EMBO journal 24 (3), 645-655, 2005 | 537 | 2005 |
Activation of caspases-8 and -10 by FLIPL KM Boatright, C Deis, JB Denault, DP Sutherlin, GS Salvesen Biochemical journal 382 (2), 651-657, 2004 | 319 | 2004 |
Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation A Oberst, C Pop, AG Tremblay, V Blais, JB Denault, GS Salvesen, ... Journal of Biological Chemistry 285 (22), 16632-16642, 2010 | 252 | 2010 |
Ligand-induced signaling in the absence of furin processing of Notch1 G Bush, A Miyamoto, JB Denault, R Leduc, G Weinmaster Developmental biology 229 (2), 494-502, 2001 | 180 | 2001 |
Processing of proendothelin‐1 by human furin convertase JB Denault, A Claing, P D'Orléans-Juste, T Sawamura, T Kido, T Masaki, ... FEBS letters 362 (3), 276-280, 1995 | 167 | 1995 |
Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes AB Berger, MD Witte, JB Denault, AM Sadaghiani, KMB Sexton, ... Molecular cell 23 (4), 509-521, 2006 | 144 | 2006 |
Human caspase-7 activity and regulation by its N-terminal peptide JB Denault, GS Salvesen Journal of Biological Chemistry 278 (36), 34042-34050, 2003 | 135 | 2003 |
Caspase-7 uses an exosite to promote poly (ADP ribose) polymerase 1 proteolysis D Boucher, V Blais, JB Denault Proceedings of the National Academy of Sciences 109 (15), 5669-5674, 2012 | 133 | 2012 |
Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)–mediated inhibition of caspase 9 JB Denault, BP Eckelman, H Shin, C Pop, GS Salvesen Biochemical Journal 405 (1), 11-19, 2007 | 123 | 2007 |
Characterization of a secreted form of human furin endoprotease G Vidricaire, JB Denault, R Leduc Biochemical and biophysical research communications 195 (2), 1011-1018, 1993 | 110 | 1993 |
Furin/PACE/SPC1: a convertase involved in exocytic and endocytic processing of precursor proteins JB Denault, R Leduc FEBS letters 379 (2), 113-116, 1996 | 103 | 1996 |
Apoptotic caspase activation and activity JB Denault, GS Salvesen Apoptosis and Cancer: Methods and Protocols, 191-220, 2008 | 100 | 2008 |
PACE4: a subtilisin-like endoprotease with unique properties RE MAINS, CA BERARD, JB DENAULT, A ZHOU, RC JOHNSON, ... Biochemical Journal 321 (3), 587-593, 1997 | 86 | 1997 |
Expression, purification, and characterization of caspases JB Denault, GS Salvesen Current protocols in protein science 30 (1), 21.13. 1-21.13. 15, 2002 | 74 | 2002 |
Processing of proendothelin‐1 by members of the subtilisin‐like pro‐protein convertase family V Blais, M Fugère, JB Denault, K Klarskov, R Day, R Leduc FEBS letters 524 (1-3), 43-48, 2002 | 68 | 2002 |
Carboxyl-terminal proteolytic processing of CUX1 by a caspase enables transcriptional activation in proliferating cells M Truscott, JB Denault, B Goulet, L Leduy, GS Salvesen, A Nepveu Journal of Biological Chemistry 282 (41), 30216-30226, 2007 | 60 | 2007 |
Yersinia phosphatase induces mitochondrially dependent apoptosis of T cells S Bruckner, S Rhamouni, L Tautz, JB Denault, A Alonso, B Becattini, ... Journal of Biological Chemistry 280 (11), 10388-10394, 2005 | 57 | 2005 |
Caspase-8 cleaves histone deacetylase 7 and abolishes its transcription repressor function FL Scott, GJ Fuchs, SE Boyd, JB Denault, CJ Hawkins, F Dequiedt, ... Journal of Biological Chemistry 283 (28), 19499-19510, 2008 | 55 | 2008 |
Engineered hybrid dimers: tracking the activation pathway of caspase-7 JB Denault, M Békés, FL Scott, KMB Sexton, M Bogyo, GS Salvesen Molecular cell 23 (4), 523-533, 2006 | 52 | 2006 |