Poly (ADP-ribose) polymerase 1 searches DNA via a ‘monkey bar’mechanism J Rudolph, J Mahadevan, P Dyer, K Luger Elife 7, e37818, 2018 | 80 | 2018 |
The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer J Rudolph, UM Muthurajan, M Palacio, J Mahadevan, G Roberts, ... Molecular cell 81 (24), 4994-5006. e5, 2021 | 65 | 2021 |
Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1 G Gaullier, G Roberts, UM Muthurajan, S Bowerman, J Rudolph, ... PLoS One 15 (11), e0240932, 2020 | 41 | 2020 |
Efficient differentiation of murine embryonic stem cells requires the binding of CXXC finger protein 1 to DNA or methylated histone H3-Lys4 J Mahadevan, DG Skalnik Gene 594 (1), 1-9, 2016 | 24 | 2016 |
Probing the conformational changes associated with DNA binding to PARP1 J Rudolph, J Mahadevan, K Luger Biochemistry 59 (21), 2003-2011, 2020 | 21 | 2020 |
Dynamics of endogenous PARP1 and PARP2 during DNA damage revealed by live-cell single-molecule imaging J Mahadevan, A Jha, J Rudolph, S Bowerman, D Narducci, AS Hansen, ... IScience 26 (1), 2023 | 15 | 2023 |
Q-FADD: a mechanistic approach for modeling the accumulation of proteins at sites of DNA damage J Mahadevan, J Rudolph, A Jha, JW Tay, J Dragavon, EM Grumstrup, ... Biophysical Journal 116 (11), 2224-2233, 2019 | 14 | 2019 |
Quantitating repair protein accumulation at DNA lesions: Past, present, and future J Mahadevan, S Bowerman, K Luger DNA repair 81, 102650, 2019 | 13 | 2019 |
Automated modeling of protein accumulation at DNA damage sites using qFADD. py S Bowerman, J Mahadevan, P Benson, J Rudolph, K Luger Biological imaging 2, e8, 2022 | 4 | 2022 |
Q-FADD: a mechanistic approach for modeling the accumulation of proteins at sites of DNA damage by free diffusion J Mahadevan, J Rudolph, A Jha, JW Tay, J Dragavon, EM Grumstrup, ... bioRxiv, 373043, 2018 | 1 | 2018 |
The role of CFP1 in murine embryonic stem cell function and liver regeneration J Mahadevan Indiana University-Purdue University Indianapolis, 2015 | 1 | 2015 |
OKI-1546 is a selective, orally bioavailable inhibitor of CDK12 that causes tumor regression in multiple preclinical cancer models AA Strait, DA Mareska, J Mahadevan, CA Schulte, Y Izrayelit, ML Boys, ... Cancer Research 83 (7_Supplement), 1635-1635, 2023 | | 2023 |
Extracting Protein Recruitment Kinetics to DNA Damage using qFADD. py S Bowerman, J Mahadevan, P Benson, J Rudolph, K Luger Biophysical Journal 120 (3), 82a-83a, 2021 | | 2021 |
Monkey Business: How to Move in the DNA Jungle. K Luger, J Rudolph, J Mahadevan, A Jha, S Bowerman, E Grumstrup ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 60, 31-32, 2019 | | 2019 |