Lymph protects metastasizing melanoma cells from ferroptosis JM Ubellacker, A Tasdogan, V Ramesh, B Shen, EC Mitchell, ... Nature 585 (7823), 113-118, 2020 | 616 | 2020 |
Metabolic heterogeneity confers differences in melanoma metastatic potential A Tasdogan, B Faubert, V Ramesh, JM Ubellacker, BO Shen, ... Nature 577 (7788), 115-120, 2020 | 384 | 2020 |
In situ capture of chromatin interactions by biotinylated dCas9 X Liu, Y Zhang, Y Chen, M Li, F Zhou, K Li, H Cao, M Ni, Y Liu, Z Gu, ... Cell 170 (5), 1028-1043. e19, 2017 | 299 | 2017 |
BCR-ABL1 compound mutations in tyrosine kinase inhibitor–resistant CML: frequency and clonal relationships JS Khorashad, TW Kelley, P Szankasi, CC Mason, S Soverini, LT Adrian, ... Blood, The Journal of the American Society of Hematology 121 (3), 489-498, 2013 | 262 | 2013 |
Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing K Li, Y Liu, H Cao, Y Zhang, Z Gu, X Liu, A Yu, P Kaphle, KE Dickerson, ... Nature communications 11 (1), 485, 2020 | 196 | 2020 |
Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation X Liu, Y Zhang, M Ni, H Cao, RAJ Signer, D Li, M Li, Z Gu, Z Hu, ... Nature cell biology 19 (6), 626-638, 2017 | 142 | 2017 |
Loss of EZH2 reprograms BCAA metabolism to drive leukemic transformation Z Gu, Y Liu, F Cai, MK Patrick, J Zmajkovic, H Cao, Y Zhang, A Tasdogan, ... Cancer discovery 9 (9), 1228-1247, 2019 | 136 | 2019 |
NEK2 promotes aerobic glycolysis in multiple myeloma through regulating splicing of pyruvate kinase Z Gu, J Xia, H Xu, I Frech, G Tricot, F Zhan Journal of hematology & oncology 10, 1-11, 2017 | 116 | 2017 |
Decreased ferroportin promotes myeloma cell growth and osteoclast differentiation Z Gu, H Wang, J Xia, Y Yang, Z Jin, H Xu, J Shi, I De Domenico, G Tricot, ... Cancer research 75 (11), 2211-2221, 2015 | 103 | 2015 |
Bruton tyrosine kinase is a therapeutic target in stem-like cells from multiple myeloma Y Yang, J Shi, Z Gu, ME Salama, S Das, E Wendlandt, H Xu, J Huang, ... Cancer research 75 (3), 594-604, 2015 | 83 | 2015 |
RARα2 expression confers myeloma stem cell features Y Yang, J Shi, G Tolomelli, H Xu, J Xia, H Wang, W Zhou, Y Zhou, S Das, ... Blood, The Journal of the American Society of Hematology 122 (8), 1437-1447, 2013 | 78 | 2013 |
Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma R Franqui-Machin, M Hao, H Bai, Z Gu, X Zhan, H Habelhah, Y Jethava, ... The Journal of clinical investigation 128 (7), 2877-2893, 2018 | 77 | 2018 |
ALDH1 activity identifies tumor-initiating cells and links to chromosomal instability signatures in multiple myeloma W Zhou, Y Yang, Z Gu, H Wang, J Xia, X Wu, X Zhan, D Levasseur, ... Leukemia 28 (5), 1155-1158, 2014 | 73 | 2014 |
Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells Y Huang, Q Zhao, CX Zhou, ZM Gu, D Li, HZ Xu, PJ Sims, KW Zhao, ... Oncogene 25 (50), 6618-6627, 2006 | 67 | 2006 |
NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma Y Yang, W Zhou, J Xia, Z Gu, E Wendlandt, X Zhan, S Janz, G Tricot, ... Oncotarget 5 (23), 11986, 2014 | 66 | 2014 |
Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia Z Gu, Y Liu, Y Zhang, H Cao, J Lyu, X Wang, A Wylie, SJ Newkirk, ... Nature genetics 53 (5), 672-682, 2021 | 63 | 2021 |
Pharicin B stabilizes retinoic acid receptor-α and presents synergistic differentiation induction with ATRA in myeloid leukemic cells ZM Gu, YL Wu, MY Zhou, CX Liu, HZ Xu, H Yan, Y Zhao, Y Huang, ... Blood, The Journal of the American Society of Hematology 116 (24), 5289-5297, 2010 | 58 | 2010 |
Role of NEK2A in human cancer and its therapeutic potentials J Xia, R Franqui Machin, Z Gu, F Zhan BioMed research international 2015 (1), 862461, 2015 | 49 | 2015 |
Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells KE Brandt, KC Falls, JD Schoenfeld, SN Rodman, Z Gu, F Zhan, JJ Cullen, ... Redox biology 14, 82-87, 2018 | 45 | 2018 |
NEDD8 inhibition overcomes CKS1B-induced drug resistance by upregulation of p21 in multiple myeloma J Huang, Y Zhou, GS Thomas, Z Gu, Y Yang, H Xu, G Tricot, F Zhan Clinical Cancer Research 21 (24), 5532-5542, 2015 | 43 | 2015 |