The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast NP Sharp, L Sandell, CG James, SP Otto Proceedings of the National Academy of Sciences 115 (22), E5046-E5055, 2018 | 131 | 2018 |
Evidence for elevated mutation rates in low-quality genotypes NP Sharp, AF Agrawal Proceedings of the National Academy of Sciences 109 (16), 6142-6146, 2012 | 104 | 2012 |
Local adaptation interacts with expansion load during range expansion: maladaptation reduces expansion load KJ Gilbert, NP Sharp, AL Angert, GL Conte, JA Draghi, F Guillaume, ... The American Naturalist 189 (4), 368-380, 2017 | 99 | 2017 |
Male‐biased fitness effects of spontaneous mutations in Drosophila melanogaster NP Sharp, AF Agrawal Evolution 67 (4), 1189-1195, 2013 | 89 | 2013 |
MATING DENSITY AND THE STRENGTH OF SEXUAL SELECTION AGAINST DELETERIOUS ALLELES IN DROSOPHILA MELANOGASTER NP Sharp, AF Agrawal Evolution: International Journal of Organic Evolution 62 (4), 857-867, 2008 | 88 | 2008 |
Sexual antagonism for resistance and tolerance to infection in Drosophila melanogaster CM Vincent, NP Sharp Proceedings of the Royal Society B: Biological Sciences 281 (1788), 20140987, 2014 | 79 | 2014 |
Low Genetic Quality Alters Key Dimensions of the Mutational Spectrum NP Sharp, AF Agrawal PLoS Biology 14 (3), e1002419, 2016 | 50 | 2016 |
Evolution of sex: Using experimental genomics to select among competing theories NP Sharp, SP Otto Bioessays 38 (8), 751-757, 2016 | 38 | 2016 |
Selection, Epistasis, and Parent‐of‐Origin Effects on Deleterious Mutations across Environments in Drosophila melanogaster AD Wang, NP Sharp, CC Spencer, K Tedman-Aucoin, AF Agrawal The American Naturalist 174 (6), 863-874, 2009 | 36 | 2009 |
Sexual Selection and the Random Union of Gametes: Testing for a Correlation in Fitness between Mates in Drosophila melanogaster NP Sharp, AF Agrawal The American Naturalist 174 (5), 613-622, 2009 | 27 | 2009 |
Fitness effects of mutations: an assessment of PROVEAN predictions using mutation accumulation data L Sandell, NP Sharp Genome biology and evolution 14 (1), evac004, 2022 | 26 | 2022 |
Relative effectiveness of mating success and sperm competition at eliminating deleterious mutations in Drosophila melanogaster SCA Clark, NP Sharp, L Rowe, AF Agrawal PLoS One 7 (5), e37351, 2012 | 23 | 2012 |
The population genetics of ploidy change in unicellular fungi AC Gerstein, NP Sharp FEMS microbiology reviews 45 (5), fuab006, 2021 | 22 | 2021 |
An experimental test of the mutation-selection balance model for the maintenance of genetic variance in fitness components NP Sharp, AF Agrawal Proceedings of the Royal Society B 285 (1890), 20181864, 2018 | 22 | 2018 |
Sensitivity of the distribution of mutational fitness effects to environment, genetic background, and adaptedness: a case study with Drosophila AD Wang, NP Sharp, AF Agrawal Evolution 68 (3), 840-853, 2014 | 22 | 2014 |
The effect of parasites on sex differences in selection NP Sharp, CM Vincent Heredity 114 (4), 367-372, 2015 | 21 | 2015 |
Mutations matter even if proteins stay the same N Sharp Nature 606 (7915), 657-659, 2022 | 12 | 2022 |
Are mutations usually deleterious? A perspective on the fitness effects of mutation accumulation K Bao, RH Melde, NP Sharp Evolutionary Ecology 36 (5), 753-766, 2022 | 11 | 2022 |
The decline in fitness with inbreeding: evidence for negative dominance‐by‐dominance epistasis in Drosophila melanogaster NP Sharp, AF Agrawal Journal of evolutionary biology 29 (4), 857-864, 2016 | 10 | 2016 |
Recent insights into the evolution of mutation rates in yeast RH Melde, K Bao, NP Sharp Current opinion in genetics & development 76, 101953, 2022 | 5 | 2022 |