Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ... Science 352 (6282), 189-196, 2016 | 3941 | 2016 |
Cells on chips J El-Ali, PK Sorger, KF Jensen Nature 442 (7101), 403-411, 2006 | 2666 | 2006 |
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis SL Spencer, S Gaudet, JG Albeck, JM Burke, PK Sorger Nature 459 (7245), 428-432, 2009 | 1205 | 2009 |
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 1046 | 2018 |
Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation PK Sorger, HRB Pelham Cell 54 (6), 855-864, 1988 | 1012 | 1988 |
MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells LS Michel, V Liberal, A Chatterjee, R Kirchwegger, B Pasche, W Gerald, ... Nature 409 (6818), 355-359, 2001 | 947 | 2001 |
SARS-CoV-2 infection protects against rechallenge in rhesus macaques A Chandrashekar, J Liu, AJ Martinot, K McMahan, NB Mercado, L Peter, ... Science 369 (6505), 812-817, 2020 | 938 | 2020 |
Heat shock factor and the heat shock response PK Sorger Cell 65 (3), 363-366, 1991 | 817 | 1991 |
Physicochemical modelling of cell signalling pathways BB Aldridge, JM Burke, DA Lauffenburger, PK Sorger Nature cell biology 8 (11), 1195-1203, 2006 | 772 | 2006 |
Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks MJ Lee, SY Albert, AK Gardino, AM Heijink, PK Sorger, G MacBeath, ... Cell 149 (4), 780-794, 2012 | 738 | 2012 |
Electronic detection of DNA by its intrinsic molecular charge J Fritz, EB Cooper, S Gaudet, PK Sorger, SR Manalis Proceedings of the National Academy of sciences 99 (22), 14142-14146, 2002 | 719 | 2002 |
A role for the Adenomatous Polyposis Coli protein in chromosome segregation KB Kaplan, AA Burds, JR Swedlow, SS Bekir, PK Sorger, IS Näthke Nature cell biology 3 (4), 429-432, 2001 | 702 | 2001 |
Systems biology and combination therapy in the quest for clinical efficacy JB Fitzgerald, B Schoeberl, UB Nielsen, PK Sorger Nature chemical biology 2 (9), 458-466, 2006 | 682 | 2006 |
Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2 M Dobles, V Liberal, ML Scott, R Benezra, PK Sorger Cell 101 (6), 635-645, 2000 | 655 | 2000 |
A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis KA Janes, JG Albeck, S Gaudet, PK Sorger, DA Lauffenburger, MB Yaffe Science 310 (5754), 1646-1653, 2005 | 637 | 2005 |
Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs M Hafner, M Niepel, M Chung, PK Sorger Nature methods 13 (6), 521-527, 2016 | 600 | 2016 |
Heat shock factor is regulated differently in yeast and HeLa cells PK Sorger, MJ Lewis, HRB Pelham Nature 329 (6134), 81-84, 1987 | 599 | 1987 |
Combination cancer therapy can confer benefit via patient-to-patient variability without drug additivity or synergy AC Palmer, PK Sorger Cell 171 (7), 1678-1691. e13, 2017 | 577 | 2017 |
Timing and checkpoints in the regulation of mitotic progression P Meraldi, VM Draviam, PK Sorger Developmental cell 7 (1), 45-60, 2004 | 559 | 2004 |
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes JR Lin, B Izar, S Wang, C Yapp, S Mei, PM Shah, S Santagata, PK Sorger elife 7, 2018 | 538 | 2018 |