The role of inflammation and inflammatory mediators in the development, progression, metastasis, and chemoresistance of epithelial ovarian cancer SS Savant, S Sriramkumar, HM O’Hagan Cancers 10 (8), 251, 2018 | 153 | 2018 |
Mismatch repair proteins initiate epigenetic alterations during inflammation-driven tumorigenesis AR Maiuri, M Peng, R Podicheti, S Sriramkumar, CM Kamplain, DB Rusch, ... Cancer research 77 (13), 3467-3478, 2017 | 53 | 2017 |
Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy CE DeStefano Shields, JR White, L Chung, A Wenzel, JL Hicks, AJ Tam, ... Cancer discovery 11 (7), 1792-1807, 2021 | 52 | 2021 |
LSD1 and Aberrant DNA Methylation Mediate Persistence of Enteroendocrine Progenitors That Support BRAF-Mutant Colorectal Cancer SA Miller, RA Policastro, S Sriramkumar, T Lai, TD Huntington, ... Cancer research 81 (14), 3791-3805, 2021 | 46 | 2021 |
Platinum-induced mitochondrial OXPHOS contributes to cancer stem cell enrichment in ovarian cancer S Sriramkumar, R Sood, TD Huntington, AH Ghobashi, TT Vuong, ... Journal of Translational Medicine 20 (1), 246, 2022 | 34 | 2022 |
Lysine-Specific Demethylase 1 Mediates AKT Activity and Promotes Epithelial-to-Mesenchymal Transition in PIK3CA-Mutant Colorectal Cancer SA Miller, RA Policastro, SS Savant, S Sriramkumar, N Ding, X Lu, ... Molecular Cancer Research 18 (2), 264-277, 2020 | 32 | 2020 |
A novel ALDH1A1 inhibitor blocks platinum-induced senescence and stemness in ovarian cancer V Muralikrishnan, F Fang, TC Given, R Podicheti, M Chtcherbinine, ... Cancers 14 (14), 3437, 2022 | 16 | 2022 |
Platinum-induced ubiquitination of phosphorylated H2AX by RING1A is mediated by replication protein A in ovarian cancer S Sriramkumar, TD Matthews, AH Ghobashi, SA Miller, ... Molecular Cancer Research 18 (11), 1699-1710, 2020 | 15 | 2020 |
Single-cell analysis of a high-grade serous ovarian cancer cell line reveals transcriptomic changes and cell subpopulations sensitive to epigenetic combination treatment S Sriramkumar, TX Metcalfe, T Lai, X Zong, F Fang, HM O’Hagan, ... Plos one 17 (8), e0271584, 2022 | 6 | 2022 |
Novel epigenetic-metabolic inhibitor combination treatment blocks platinum-induced ovarian cancer stem cell enrichment R Sood, S Xiao, S Sriramkumar, C Hassel, KP Nephew, HM O’Hagan Biorxiv, 2021 | 3 | 2021 |
LSD1 promotes secretory cell specification to drive BRAF mutant colorectal cancer SA Miller, RA Policastro, S Sriramkumar, T Lai, TD Huntington, ... bioRxiv, 2020.09. 25.313536, 2020 | 2 | 2020 |
Abstract B029: Targeting non-canonical function of TXNRD1 to overcome platinum resistance by eradicating ovarian cancer stem-like cells M Towers, X Hao, S Sriramkumar, W Zhou, R Zhang Cancer Research 84 (5_Supplement_2), B029-B029, 2024 | | 2024 |
Targeting non-canonical function of TXNRD1 to overcome platinum resistance by eradicating ovarian cancer stem-like cells M Towers, X Hao, S Sriramkumar, W Zhou, R Zhang CANCER RESEARCH 84 (5), 2024 | | 2024 |
Platinum-inducedBRCA1 promoter DNA hypermethylation and altered metabolic profile promotes chemoresistance in ovarian cancer R Sood, S Xiao, S Sriramkumar, C Hassel, K Nephew, H O'Hagan Cancer Research 81 (13_Supplement), 2110-2110, 2021 | | 2021 |
Combined epigenetic and metabolic inhibition blocks platinum-induced ovarian cancer stem cell enrichment R Sood, S Sriramkumar, V Muralikrishnan, S Xiao, W Wang, C Hassel, ... bioRxiv, 2021.03. 18.435878, 2021 | | 2021 |
The Role of Platinum-Mediated Chromatin and Metabolic Alterations in Ovarian Cancer Chemoresistance S Sriramkumar Indiana University, 2021 | | 2021 |
Abstract GMM-055: BMI1 AND RING1A ARE INVOLVED IN H2A UBIQUITINATION AT SITES OF PLATINUM-INDUCED DAMAGE S Sriramkumar, HM O'Hagan Clinical Cancer Research 25 (22_Supplement), GMM-055-GMM-055, 2019 | | 2019 |
RING1A Ubiquitinates Histone H2A at Sites of Platinum-Induced Damage. HM O'Hagan, S Sriramkumar ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 60, 52-53, 2019 | | 2019 |
BMI1 and RING1A are involved in H2A ubiquitination at sites of platinum-induced damage S Sriramkumar, HM O'Hagan Cancer Research 79 (13_Supplement), 2576-2576, 2019 | | 2019 |
Mismatch Repair Proteins Initiate Epigenetic Alterations during Inflammation-Driven Tumorigenesis (vol 77, pg 3467, 2017) AR Maiuri, M Peng, R Podicheti, S Sriramkumar, CM Kamplain, DB Rusch, ... CANCER RESEARCH 78 (2), 584-584, 2018 | | 2018 |