Solid lipid nanoparticles as intracellular drug transporters: an investigation of the uptake mechanism and pathway S Martins, S Costa-Lima, T Carneiro, A Cordeiro-da-Silva, EB Souto, ... International journal of pharmaceutics 430 (1-2), 216-227, 2012 | 197 | 2012 |
Mucoadhesive chitosan-coated solid lipid nanoparticles for better management of tuberculosis ACC Vieira, LL Chaves, S Pinheiro, S Pinto, M Pinheiro, SC Lima, ... International journal of pharmaceutics 536 (1), 478-485, 2018 | 127 | 2018 |
A new topical formulation for psoriasis: development of methotrexate-loaded nanostructured lipid carriers MF Pinto, CC Moura, C Nunes, MA Segundo, SAC Lima, S Reis International journal of pharmaceutics 477 (1-2), 519-526, 2014 | 120 | 2014 |
Biodegradation of p-chlorophenol by a microalgae consortium SAC Lima, MFJ Raposo, PML Castro, RM Morais Water Research 38 (1), 97-102, 2004 | 117 | 2004 |
Marine polysaccharides in pharmaceutical applications: Fucoidan and chitosan as key players in the drug delivery match field AI Barbosa, AJ Coutinho, SA Costa Lima, S Reis Marine Drugs 17 (12), 654, 2019 | 114 | 2019 |
Apo E-functionalization of solid lipid nanoparticles enhances brain drug delivery: uptake mechanism and transport pathways AR Neves, JF Queiroz, SAC Lima, S Reis Bioconjugate chemistry 28 (4), 995-1004, 2017 | 109 | 2017 |
Optimization of nanostructured lipid carriers loaded with methotrexate: A tool for inflammatory and cancer therapy M Ferreira, LL Chaves, SAC Lima, S Reis International journal of pharmaceutics 492 (1-2), 65-72, 2015 | 106 | 2015 |
Cellular uptake and transcytosis of lipid-based nanoparticles across the intestinal barrier: relevance for oral drug delivery AR Neves, JF Queiroz, SAC Lima, F Figueiredo, R Fernandes, S Reis Journal of colloid and interface science 463, 258-265, 2016 | 105 | 2016 |
Application of pH-responsive fucoidan/chitosan nanoparticles to improve oral quercetin delivery AI Barbosa, SA Costa Lima, S Reis Molecules 24 (2), 346, 2019 | 100 | 2019 |
Temperature-responsive polymeric nanospheres containing methotrexate and gold nanoparticles: A multi-drug system for theranostic in rheumatoid arthritis SAC Lima, S Reis Colloids and Surfaces B: Biointerfaces 133, 378-387, 2015 | 88 | 2015 |
Development of methotrexate loaded fucoidan/chitosan nanoparticles with anti-inflammatory potential and enhanced skin permeation AI Barbosa, SAC Lima, S Reis International journal of biological macromolecules 124, 1115-1122, 2019 | 86 | 2019 |
Mucoadhesive and pH responsive fucoidan-chitosan nanoparticles for the oral delivery of methotrexate AJ Coutinho, SAC Lima, CMM Afonso, S Reis International journal of biological macromolecules 158, 180-188, 2020 | 74 | 2020 |
Role of inflammasome genetics in susceptibility to HPV infection and cervical cancer development A Pontillo, P Bricher, VNC Leal, S Lima, PRE Souza, S Crovella Journal of medical virology 88 (9), 1646-1651, 2016 | 74 | 2016 |
In vitro study of P-glycoprotein induction as an antidotal pathway to prevent cytotoxicity in Caco-2 cells R Silva, H Carmo, R Dinis-Oliveira, A Cordeiro-da-Silva, SC Lima, ... Archives of toxicology 85, 315-326, 2011 | 74 | 2011 |
Mannosylated solid lipid nanoparticles for the selective delivery of rifampicin to macrophages ACC Vieira, LL Chaves, M Pinheiro, SAC Lima, D Ferreira, B Sarmento, ... Artificial cells, nanomedicine, and biotechnology 46 (sup1), 653-663, 2018 | 73 | 2018 |
Synthesis and anti-parasitic activity of a novel quinolinone–chalcone series M Roussaki, B Hall, SC Lima, AC da Silva, S Wilkinson, A Detsi Bioorganic & medicinal chemistry letters 23 (23), 6436-6441, 2013 | 72 | 2013 |
Aurones: a promising heterocyclic scaffold for the development of potent antileishmanial agents M Roussaki, S Costa Lima, AM Kypreou, P Kefalas, A Cordeiro da Silva, ... International journal of medicinal chemistry 2012 (1), 196921, 2012 | 70 | 2012 |
Biodegradation of p-nitrophenol by microalgae SAC Lima, PML Castro, R Morais Journal of applied phycology 15, 137-142, 2003 | 64 | 2003 |
Recommendations for in vitro and in vivo testing of magnetic nanoparticle hyperthermia combined with radiation therapy SV Spirou, SA Costa Lima, P Bouziotis, S Vranješ-Djurić, EΚ Efthimiadou, ... Nanomaterials 8 (5), 306, 2018 | 59 | 2018 |
Human skin models: From healthy to disease‐mimetic systems; characteristics and applications T Moniz, SA Costa Lima, S Reis British journal of pharmacology 177 (19), 4314-4329, 2020 | 57 | 2020 |