EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair E Ezhkova, WH Lien, N Stokes, HA Pasolli, JM Silva, E Fuchs Genes & development 25 (5), 485-498, 2011 | 418 | 2011 |
DNA methylation dynamics during in vivo differentiation of blood and skin stem cells C Bock, I Beerman, WH Lien, ZD Smith, H Gu, P Boyle, A Gnirke, E Fuchs, ... Molecular cell 47 (4), 633-647, 2012 | 409 | 2012 |
α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1 MR Silvis, BT Kreger, WH Lien, O Klezovitch, GM Rudakova, FD Camargo, ... Science signaling 4 (174), ra33-ra33, 2011 | 385 | 2011 |
Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling WH Lien, E Fuchs Genes & development 28 (14), 1517-1532, 2014 | 284 | 2014 |
αE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway WH Lien, O Klezovitch, TE Fernandez, J Delrow, V Vasioukhin Science 311 (5767), 1609-1612, 2006 | 278 | 2006 |
In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators WH Lien, L Polak, M Lin, K Lay, D Zheng, E Fuchs Nature cell biology 16 (2), 179-190, 2014 | 226 | 2014 |
Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage WH Lien, X Guo, L Polak, LN Lawton, RA Young, D Zheng, E Fuchs Cell stem cell 9 (3), 219-232, 2011 | 217 | 2011 |
RNAi screens in mice identify physiological regulators of oncogenic growth S Beronja, P Janki, E Heller, WH Lien, BE Keyes, N Oshimori, E Fuchs Nature 501 (7466), 185-190, 2013 | 191 | 2013 |
Nfatc1 orchestrates aging in hair follicle stem cells BE Keyes, JP Segal, E Heller, WH Lien, CY Chang, X Guo, DS Oristian, ... Proceedings of the National Academy of Sciences 110 (51), E4950-E4959, 2013 | 184 | 2013 |
αE-catenin inhibits a Src–YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway P Li, MR Silvis, Y Honaker, WH Lien, ST Arron, V Vasioukhin Genes & development 30 (7), 798-811, 2016 | 180 | 2016 |
Concise review: Wnt signaling pathways in skin development and epidermal stem cells A Veltri, C Lang, WH Lien Stem Cells 36 (1), 22-35, 2018 | 137 | 2018 |
Cadherin–catenin proteins in vertebrate development WH Lien, O Klezovitch, V Vasioukhin Current opinion in cell biology 18 (5), 499-506, 2006 | 110 | 2006 |
Distinct regulation of genes by bFGF and VEGF-A in endothelial cells YJ Jih, WH Lien, WC Tsai, GW Yang, C Li, LW Wu Angiogenesis 4, 313-321, 2001 | 110 | 2001 |
Temporal layering of signaling effectors drives chromatin remodeling during hair follicle stem cell lineage progression RC Adam, H Yang, Y Ge, WH Lien, P Wang, Y Zhao, L Polak, J Levorse, ... Cell stem cell 22 (3), 398-413. e7, 2018 | 100 | 2018 |
Llgl1 connects cell polarity with cell-cell adhesion in embryonic neural stem cells Y Jossin, M Lee, O Klezovitch, E Kon, A Cossard, WH Lien, TE Fernandez, ... Developmental cell 41 (5), 481-495. e5, 2017 | 63 | 2017 |
Comparison of REST cistromes across human cell types reveals common and context-specific functions S Rockowitz, WH Lien, E Pedrosa, G Wei, M Lin, K Zhao, HM Lachman, ... PLoS computational biology 10 (6), e1003671, 2014 | 50 | 2014 |
Feedback regulation of apical progenitor fate by immature neurons through Wnt7–Celsr3–Fzd3 signalling W Wang, Y Jossin, G Chai, WH Lien, F Tissir, AM Goffinet Nature communications 7 (1), 10936, 2016 | 43 | 2016 |
α–E-catenin binds to dynamitin and regulates dynactin-mediated intracellular traffic WH Lien, VI Gelfand, V Vasioukhin The Journal of Cell Biology 183 (6), 989-997, 2008 | 33 | 2008 |
Wnt signaling pathways in keratinocyte carcinomas CMR Lang, CK Chan, A Veltri, WH Lien Cancers 11 (9), 1216, 2019 | 32 | 2019 |
Participation of cyclin D1 deregulation in TNP-470-mediated cytostatic effect: involvement of senescence WH Lien, CK Chen, LY Lai, YH Chen, MP Wu, LW Wu Biochemical pharmacology 68 (4), 729-738, 2004 | 26 | 2004 |