The expanding superfamily of phospholipase A2 enzymes: classification and characterization DA Six, EA Dennis Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2000 | 1806 | 2000 |
Lipidomics reveals a remarkable diversity of lipids in human plasma O Quehenberger, AM Armando, AH Brown, SB Milne, DS Myers, ... Journal of lipid research 51 (11), 3299-3305, 2010 | 1338 | 2010 |
Discovery of new biosynthetic pathways: the lipid A story CRH Raetz, Z Guan, BO Ingram, DA Six, F Song, X Wang, J Zhao Journal of lipid research 50 (Supplement), S103-S108, 2009 | 284 | 2009 |
In vivo phospholipase activity of the Pseudomonas aeruginosa cytotoxin ExoU and protection of mammalian cells with phospholipase A2 inhibitors RM Phillips, DA Six, EA Dennis, P Ghosh Journal of Biological Chemistry 278 (42), 41326-41332, 2003 | 234 | 2003 |
Group IV cytosolic phospholipase A2 binds with high affinity and specificity to phosphatidylinositol 4, 5-bisphosphate resulting in dramatic increases in activity M Mosior, DA Six, EA Dennis Journal of Biological Chemistry 273 (4), 2184-2191, 1998 | 228 | 1998 |
VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and … JC Hamrick, JD Docquier, T Uehara, CL Myers, DA Six, CL Chatwin, ... Antimicrobial Agents and Chemotherapy 64 (3), 10.1128/aac. 01963-19, 2020 | 166 | 2020 |
Inhibition of Group IVA Cytosolic Phospholipase A2 by Novel 2-Oxoamides in Vitro, in Cells, and in Vivo G Kokotos, DA Six, V Loukas, T Smith, V Constantinou-Kokotou, ... Journal of medicinal chemistry 47 (14), 3615-3628, 2004 | 109 | 2004 |
Essential Ca2+-independent role of the group IVA cytosolic phospholipase A2 C2 domain for interfacial activity DA Six, EA Dennis Journal of Biological Chemistry 278 (26), 23842-23850, 2003 | 104 | 2003 |
Novel 2-Oxoamide Inhibitors of Human Group IVA Phospholipase A2 G Kokotos, S Kotsovolou, DA Six, V Constantinou-Kokotou, CC Beltzner, ... Journal of medicinal chemistry 45 (14), 2891-2893, 2002 | 103 | 2002 |
Subcellular Chemical Imaging of Antibiotics in Single Bacteria Using C60-Secondary Ion Mass Spectrometry H Tian, DA Six, T Krucker, JA Leeds, N Winograd Analytical chemistry 89 (9), 5050-5057, 2017 | 102 | 2017 |
Structure−Activity Relationship of 2-Oxoamide Inhibition of Group IVA Cytosolic Phospholipase A2 and Group V Secreted Phospholipase A2 DA Six, E Barbayianni, V Loukas, V Constantinou-Kokotou, ... Journal of medicinal chemistry 50 (17), 4222-4235, 2007 | 98 | 2007 |
Salmonella synthesizing 1-monophosphorylated lipopolysaccharide exhibits low endotoxic activity while retaining its immunogenicity Q Kong, DA Six, KL Roland, Q Liu, L Gu, CM Reynolds, X Wang, ... The Journal of immunology 187 (1), 412-423, 2011 | 88 | 2011 |
Phosphate groups of lipid A are essential for Salmonella enterica serovar Typhimurium virulence and affect innate and adaptive immunity Q Kong, DA Six, Q Liu, L Gu, S Wang, P Alamuri, CRH Raetz, R Curtiss III Infection and immunity 80 (9), 3215-3224, 2012 | 87 | 2012 |
Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid … J Bojkovic, DL Richie, DA Six, CM Rath, WS Sawyer, Q Hu, CR Dean Journal of bacteriology 198 (4), 731-741, 2015 | 81 | 2015 |
Iron Acquisition Systems of Gram-negative Bacterial Pathogens Define TonB-Dependent Pathways to Novel Antibiotics PE Klebba, SMC Newton, DA Six, A Kumar, T Yang, BL Nairn, C Munger, ... Chemical reviews 121 (9), 5193-5239, 2021 | 79 | 2021 |
Complex transcriptional and post‐transcriptional regulation of an enzyme for lipopolysaccharide modification K Moon, DA Six, HJ Lee, CRH Raetz, S Gottesman Molecular microbiology 89 (1), 52-64, 2013 | 62 | 2013 |
Palmitoylation State Impacts Induction of Innate and Acquired Immunity by the Salmonella enterica Serovar Typhimurium msbB Mutant Q Kong, DA Six, Q Liu, L Gu, KL Roland, CRH Raetz, R Curtiss III Infection and immunity 79 (12), 5027-5038, 2011 | 57 | 2011 |
Lipopolysaccharide (LPS) inner-core phosphates are required for complete LPS synthesis and transport to the outer membrane in Pseudomonas aeruginosa PAO1 AM DeLucia, DA Six, RE Caughlan, P Gee, I Hunt, JS Lam, CR Dean MBio 2 (4), e00142-11, 2011 | 57 | 2011 |
Differential Inhibition of Group IVA and Group VIA Phospholipases A2 by 2-Oxoamides D Stephens, E Barbayianni, V Constantinou-Kokotou, A Peristeraki, ... Journal of medicinal chemistry 49 (9), 2821-2828, 2006 | 57 | 2006 |
Purification and Mutagenesis of LpxL, the Lauroyltransferase of Escherichia coli Lipid A Biosynthesis DA Six, SM Carty, Z Guan, CRH Raetz Biochemistry 47 (33), 8623-8637, 2008 | 54 | 2008 |