| PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database X Wang, Y Shen, S Wang, S Li, W Zhang, X Liu, L Lai, J Pei, H Li Nucleic acids research 45 (W1), W356-W360, 2017 | 919 | 2017 |
| Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2 R Xiong, L Zhang, S Li, Y Sun, M Ding, Y Wang, Y Zhao, Y Wu, W Shang, ... Protein & cell 11 (10), 723-739, 2020 | 147 | 2020 |
| Ribosomal S6 protein kinase 4 promotes radioresistance in esophageal squamous cell carcinoma MY Li, LN Fan, DH Han, Z Yu, J Ma, YX Liu, PF Li, DH Zhao, J Chai, ... The Journal of clinical investigation 130 (8), 4301-4319, 2020 | 60 | 2020 |
| Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase … S Li, H Xu, S Cui, F Wu, Y Zhang, M Su, Y Gong, S Qiu, Q Jiao, C Qin, ... Journal of Medicinal Chemistry 59 (14), 6772-6790, 2016 | 59 | 2016 |
| Novel and potent inhibitors targeting DHODH, a rate-limiting enzyme in de novo pyrimidine biosynthesis, are broad-spectrum antiviral against RNA viruses … R Xiong, L Zhang, S Li, Y Sun, M Ding, Y Wang, Y Zhao, Y Wu, W Shang, ... BioRxiv, 2020.03. 11.983056, 2020 | 58 | 2020 |
| Design, synthesis, X-ray crystallographic analysis, and biological evaluation of thiazole derivatives as potent and selective inhibitors of human dihydroorotate dehydrogenase J Zhu, L Han, Y Diao, X Ren, M Xu, L Xu, S Li, Q Li, D Dong, J Huang, ... Journal of Medicinal Chemistry 58 (3), 1123-1139, 2015 | 56 | 2015 |
| Quercetin inhibits virulence properties of Porphyromas gingivalis in periodontal disease Z He, X Zhang, Z Song, L Li, H Chang, S Li, W Zhou Scientific reports 10 (1), 18313, 2020 | 49 | 2020 |
| Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFRL858R/T790M/C797S Q Li, T Zhang, S Li, L Tong, J Li, Z Su, F Feng, D Sun, Y Tong, X Wang, ... ACS medicinal chemistry letters 10 (6), 869-873, 2019 | 46 | 2019 |
| iDrug: a web-accessible and interactive drug discovery and design platform X Wang, H Chen, F Yang, J Gong, S Li, J Pei, X Liu, H Jiang, L Lai, H Li Journal of cheminformatics 6 (1), 1-8, 2014 | 43 | 2014 |
| Rational Design of Benzylidenehydrazinyl-Substituted Thiazole Derivatives as Potent Inhibitors of Human Dihydroorotate Dehydrogenase with in Vivo Anti-arthritic … S Li, G Luan, X Ren, W Song, L Xu, M Xu, J Zhu, D Dong, Y Diao, X Liu, ... Scientific Reports 5 (1), 14836, 2015 | 39 | 2015 |
| Systematic analysis of the multiple bioactivities of green tea through a network pharmacology approach S Zhang, L Shan, Q Li, X Wang, S Li, Y Zhang, J Fu, X Liu, H Li, W Zhang Evidence-based complementary and alternative medicine 2014, 2014 | 39 | 2014 |
| Multi-body interactions in molecular docking program devised with key water molecules in protein binding sites W Xiao, D Wang, Z Shen, S Li, H Li Molecules 23 (9), 2321, 2018 | 33 | 2018 |
| Discovery of a natural-product-derived preclinical candidate for once-weekly treatment of type 2 diabetes S Li, C Qin, S Cui, H Xu, F Wu, J Wang, M Su, X Fang, D Li, Q Jiao, ... Journal of medicinal chemistry 62 (5), 2348-2361, 2019 | 32 | 2019 |
| Identification of inhibitors against p90 ribosomal S6 kinase 2 (RSK2) through structure-based virtual screening with the inhibitor-constrained refined homology model S Li, Y Zhou, W Lu, Y Zhong, W Song, K Liu, J Huang, Z Zhao, Y Xu, X Liu, ... Journal of chemical information and modeling 51 (11), 2939-2947, 2011 | 28 | 2011 |
| A broad antiviral strategy: Inhibitors of human DHODH pave the way for host-targeting antivirals against emerging and re-emerging viruses Y Zheng, S Li, K Song, J Ye, W Li, Y Zhong, Z Feng, S Liang, Z Cai, K Xu Viruses 14 (5), 928, 2022 | 27 | 2022 |
| Deep learning based drug metabolites prediction D Wang, W Liu, Z Shen, L Jiang, J Wang, S Li, H Li Frontiers in Pharmacology 10, 1586, 2020 | 26 | 2020 |
| Design, synthesis and biological evaluation of 3-piperazinecarboxylate sarsasapogenin derivatives as potential multifunctional anti-Alzheimer agents GX Yang, SL Ge, Y Wu, J Huang, SL Li, R Wang, L Ma European Journal of Medicinal Chemistry 156, 206-215, 2018 | 26 | 2018 |
| SwinOCSR: end-to-end optical chemical structure recognition using a Swin Transformer Z Xu, J Li, Z Yang, S Li, H Li Journal of Cheminformatics 14 (1), 1-13, 2022 | 25 | 2022 |
| Lipopolysaccharide preparation derived from Porphyromonas gingivalis induces a weaker immuno-inflammatory response in BV-2 microglial cells than Escherichia coli by … C Qiu, Z Yuan, Z He, H Chen, Y Liao, S Li, W Zhou, Z Song Frontiers in Cellular and Infection Microbiology 11, 606986, 2021 | 21 | 2021 |
| G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders TS Wong, G Li, S Li, W Gao, G Chen, S Gan, M Zhang, H Li, S Wu, Y Du Signal Transduction and Targeted Therapy 8 (1), 177, 2023 | 19 | 2023 |
