C5aR1 antagonism alters microglial polarization and mitigates disease progression in a mouse model of Alzheimer’s disease A Gomez-Arboledas, K Carvalho, G Balderrama-Gutierrez, SH Chu, ... Acta neuropathologica communications 10 (1), 116, 2022 | 28 | 2022 |
Modulation of C5a–C5aR1 signaling alters the dynamics of AD progression K Carvalho, ND Schartz, G Balderrama-Gutierrez, HY Liang, SH Chu, ... Journal of neuroinflammation 19 (1), 178, 2022 | 25 | 2022 |
The ENCODE4 long-read RNA-seq collection reveals distinct classes of transcript structure diversity F Reese, B Williams, G Balderrama-Gutierrez, D Wyman, MH Çelik, ... bioRxiv, 2023 | 18 | 2023 |
Single-cell and nucleus RNA-seq in a mouse model of AD reveal activation of distinct glial subpopulations in the presence of plaques and tangles G Balderrama-Gutierrez, H Liang, N Rezaie, K Carvalho, S Forner, ... BioRxiv, 2021.09. 29.462436, 2021 | 8 | 2021 |
Uncovering the gene regulatory networks underlying macrophage polarization through comparative analysis of bulk and single-cell data K Carvalho, E Rebboah, C Jansen, K Williams, A Dowey, C McGill, ... bioRxiv, 2021.01. 20.427499, 2021 | 8 | 2021 |
Inorganic pyrophosphatase from the red flour beetle (Tribolium castaneum) modulates mitochondrial polyphosphate metabolism B Mirra, K Carvalho, L Ribeiro, J Moraes, JR da Silva, EP Costa, ... Archives of insect biochemistry and physiology 102 (4), e21606, 2019 | 3 | 2019 |
C5aR1 antagonism suppresses inflammatory glial gene expression and alters cellular signaling in an aggressive Alzheimer’s model ND Schartz, HY Liang, K Carvalho, SH Chu, A Mendoza-Arvilla, ... bioRxiv, 2023 | 2 | 2023 |
A Soluble Pyrophosphatase Is Essential to Oogenesis and Is Required for Polyphosphate Metabolism in the Red Flour Beetle (Tribolium castaneum) K Carvalho, L Ribeiro, J Moraes, JR Da Silva, EP Costa, ... International Journal of Molecular Sciences 16 (4), 6631-6644, 2015 | 2 | 2015 |
C5aR1 antagonism suppresses inflammatory glial responses and alters cellular signaling in an Alzheimer’s disease mouse model ND Schartz, HY Liang, K Carvalho, SH Chu, A Mendoza-Arvilla, ... Nature Communications 15 (1), 7028, 2024 | 1 | 2024 |
Treatment with C5aR1 antagonist attenuates short‐term hippocampal memory decline and prevents DAM signature in Arctic mice. ND Schartz, K Carvalho, HY Liang, SH Chu, A Mortazavi, AJ Tenner Alzheimer's & Dementia 18, e066806, 2022 | | 2022 |
C5aR1 deletion delays amyloid-associated inflammatory gene expression and microglial activation in the Arctic model of Alzheimer's disease N Schartz, K Carvalho, A Gomez-Arboledas, G Balderrama-Gutierrez, ... MOLECULAR IMMUNOLOGY 141, 142-142, 2022 | | 2022 |
C5a overexpression alters gene expression and microglial activation in brain of the Arctic model of Alzheimer's disease N Schartz, K Carvalho, T Petrisko, G Balderrama-Gutierrez, H Liang, ... MOLECULAR IMMUNOLOGY 141, 140-141, 2022 | | 2022 |
Gene Expression and Chromatin Dynamics During Macrophage Polarization in Health and Disease K Carvalho University of California, Irvine, 2021 | | 2021 |