HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models TTT Nguyen, Y Zhang, E Shang, C Shu, C Torrini, J Zhao, E Bianchetti, ... The Journal of clinical investigation 130 (7), 3699-3716, 2020 | 130 | 2020 |
Induction of synthetic lethality in IDH1-mutated gliomas through inhibition of Bcl-xL G Karpel-Massler, CT Ishida, E Bianchetti, Y Zhang, C Shu, T Tsujiuchi, ... Nature communications 8 (1), 1067, 2017 | 118 | 2017 |
Metabolic reprogramming by dual AKT/ERK inhibition through imipridones elicits unique vulnerabilities in glioblastoma CT Ishida, Y Zhang, E Bianchetti, C Shu, TTT Nguyen, G Kleiner, ... Clinical Cancer Research 24 (21), 5392-5406, 2018 | 76 | 2018 |
Inhibition of mitochondrial matrix chaperones and antiapoptotic Bcl-2 family proteins empower antitumor therapeutic responses G Karpel-Massler, CT Ishida, E Bianchetti, C Shu, R Perez-Lorenzo, ... Cancer research 77 (13), 3513-3526, 2017 | 65 | 2017 |
Stasimon contributes to the loss of sensory synapses and motor neuron death in a mouse model of spinal muscular atrophy CM Simon, M Van Alstyne, F Lotti, E Bianchetti, S Tisdale, DM Watterson, ... Cell reports 29 (12), 3885-3901. e5, 2019 | 48 | 2019 |
Combined HDAC and bromodomain protein inhibition reprograms tumor cell metabolism and elicits synthetic lethality in glioblastoma Y Zhang, CT Ishida, W Ishida, SFL Lo, J Zhao, C Shu, E Bianchetti, ... Clinical Cancer Research 24 (16), 3941-3954, 2018 | 43 | 2018 |
Activation of LXR β inhibits tumor respiration and is synthetically lethal with Bcl‐xL inhibition TTT Nguyen, CT Ishida, E Shang, C Shu, C Torrini, Y Zhang, E Bianchetti, ... EMBO Molecular Medicine 11 (10), e10769, 2019 | 42 | 2019 |
ATF3 is a novel nuclear marker for migrating ependymal stem cells in the rat spinal cord M Mladinic, E Bianchetti, A Dekanic, GL Mazzone, A Nistri Stem Cell Research 12 (3), 815-827, 2014 | 40 | 2014 |
MET inhibition elicits PGC1α-dependent metabolic reprogramming in glioblastoma Y Zhang, TTT Nguyen, E Shang, A Mela, N Humala, A Mahajan, J Zhao, ... Cancer research 80 (1), 30-43, 2020 | 39 | 2020 |
BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma. SMD Ishida CT, Bianchetti E, Shu C, Halatsch ME, Westhoff MA, Karpel-Massler G Oncotarget, 2017 | 39 | 2017 |
Mechanisms underlying cell death in ischemia-like damage to the rat spinal cord in vitro E Bianchetti, M Mladinic, A Nistri Cell death & disease 4 (7), e707-e707, 2013 | 29 | 2013 |
Activation of LXR receptors and inhibition of TRAP1 causes synthetic lethality in solid tumors TTT Nguyen, CT Ishida, E Shang, C Shu, E Bianchetti, G Karpel-Massler, ... Cancers 11 (6), 788, 2019 | 21 | 2019 |
Dual Inhibition of Bcl-2/Bcl-xL and XPO1 is synthetically lethal in glioblastoma model systems E Shang, Y Zhang, C Shu, CT Ishida, E Bianchetti, MA Westhoff, ... Scientific Reports 8 (1), 15383, 2018 | 21 | 2018 |
The volatile anesthetic methoxyflurane protects motoneurons against excitotoxicity in an in vitro model of rat spinal cord injury A Shabbir, E Bianchetti, A Nistri Neuroscience 285, 269-280, 2015 | 18 | 2015 |
Unusual increase in lumbar network excitability of the rat spinal cord evoked by the PARP-1 inhibitor PJ-34 through inhibition of glutamate uptake SE Nasrabady, A Kuzhandaivel, A Akrami, E Bianchetti, M Milanese, ... Neuropharmacology 63 (3), 415-426, 2012 | 17 | 2012 |
Usp9X regulates cell death in malignant peripheral nerve sheath tumors E Bianchetti, SJ Bates, SL Carroll, MD Siegelin, KA Roth Scientific reports 8 (1), 17390, 2018 | 16 | 2018 |
Role of HSP70 in motoneuron survival after excitotoxic stress in a rat spinal cord injury model in vitro A Shabbir, E Bianchetti, R Cargonja, A Petrovic, M Mladinic, K Pilipović, ... European journal of neuroscience 42 (12), 3054-3065, 2015 | 16 | 2015 |
Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastoma Y Zhang, CT Ishida, C Shu, G Kleiner, MJ Sanchez-Quintero, E Bianchetti, ... Scientific Reports 8 (1), 7373, 2018 | 13 | 2018 |
BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma. Oncotarget 8, 29558–29573 CT Ishida, E Bianchetti, C Shu, ME Halatsch, MA Westhoff, ... | 7 | 2017 |
RAB38 facilitates energy metabolism and counteracts cell death in glioblastoma cells E Bianchetti, SJ Bates, TTT Nguyen, MD Siegelin, KA Roth Cells 10 (7), 1643, 2021 | 5 | 2021 |