Human immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of-fitness mutations C Pastore, R Nedellec, A Ramos, S Pontow, L Ratner, DE Mosier Journal of virology 80 (2), 750-758, 2006 | 195 | 2006 |
Electron-microscopy-based epitope mapping defines specificities of polyclonal antibodies elicited during HIV-1 BG505 envelope trimer immunization M Bianchi, HL Turner, B Nogal, CA Cottrell, D Oyen, M Pauthner, ... Immunity 49 (2), 288-300. e8, 2018 | 182 | 2018 |
Fitness epistasis and constraints on adaptation in a human immunodeficiency virus type 1 protein region J Da Silva, M Coetzer, R Nedellec, C Pastore, DE Mosier Genetics 185 (1), 293-303, 2010 | 155 | 2010 |
Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide H Gaertner, F Cerini, JM Escola, G Kuenzi, A Melotti, R Offord, ... Proceedings of the National Academy of Sciences 105 (46), 17706-17711, 2008 | 155 | 2008 |
Vaccine-induced protection from homologous tier 2 SHIV challenge in nonhuman primates depends on serum-neutralizing antibody titers MG Pauthner, JP Nkolola, C Havenar-Daughton, B Murrell, SM Reiss, ... Immunity 50 (1), 241-252. e6, 2019 | 144 | 2019 |
Human anti-anthrax protective antigen neutralizing monoclonal antibodies derived from donors vaccinated with anthrax vaccine adsorbed R Sawada-Hirai, I Jiang, F Wang, SM Sun, R Nedellec, P Ruther, ... Journal of immune based therapies and vaccines 2, 1-15, 2004 | 134 | 2004 |
Zika virus activates de novo and cross-reactive memory B cell responses in dengue-experienced donors TF Rogers, EC Goodwin, B Briney, D Sok, N Beutler, A Strubel, ... Science immunology 2 (14), eaan6809, 2017 | 112 | 2017 |
HIV-1 subtype A envelope variants from early in infection have variable sensitivity to neutralization and to inhibitors of viral entry CA Blish, R Nedellec, K Mandaliya, DE Mosier, J Overbaugh Aids 21 (6), 693-702, 2007 | 97 | 2007 |
Long-primed germinal centres with enduring affinity maturation and clonal migration JH Lee, HJ Sutton, CA Cottrell, I Phung, G Ozorowski, LM Sewall, ... Nature 609 (7929), 998-1004, 2022 | 93 | 2022 |
Primary infection by a human immunodeficiency virus with atypical coreceptor tropism C Jiang, NF Parrish, CB Wilen, H Li, Y Chen, JW Pavlicek, A Berg, X Lu, ... Journal of virology 85 (20), 10669-10681, 2011 | 77 | 2011 |
Extreme genetic divergence is required for coreceptor switching in HIV-1 subtype C M Coetzer, R Nedellec, T Cilliers, T Meyers, L Morris, DE Mosier JAIDS Journal of Acquired Immune Deficiency Syndromes 56 (1), 9-15, 2011 | 61 | 2011 |
Virus entry via the alternative coreceptors CCR3 and FPRL1 differs by human immunodeficiency virus type 1 subtype R Nedellec, M Coetzer, N Shimizu, H Hoshino, VR Polonis, L Morris, ... Journal of virology 83 (17), 8353-8363, 2009 | 54 | 2009 |
Resistance to the CCR5 inhibitor 5P12-RANTES requires a difficult evolution from CCR5 to CXCR4 coreceptor use R Nedellec, M Coetzer, MM Lederman, RE Offord, O Hartley, DE Mosier PloS one 6 (7), e22020, 2011 | 52 | 2011 |
Cloning and characterization of functional subtype A HIV-1 envelope variants transmitted through breastfeeding SMJ Rainwater, X Wu, R Nduati, R Nedellec, D Mosier, G John-Stewart, ... Current HIV research 5 (2), 189-197, 2007 | 48 | 2007 |
Evolution of CCR5 use before and during coreceptor switching M Coetzer, R Nedellec, J Salkowitz, S McLaughlin, Y Liu, L Heath, ... Journal of virology 82 (23), 11758-11766, 2008 | 47 | 2008 |
Conserved changes in envelope function during human immunodeficiency virus type 1 coreceptor switching C Pastore, R Nedellec, A Ramos, O Hartley, JL Miamidian, JD Reeves, ... Journal of virology 81 (15), 8165-8179, 2007 | 37 | 2007 |
Human monoclonal antibodies that neutralize anthrax toxin by inhibiting heptamer assembly F Wang, P Ruther, I Jiang, R Sawada-Hirai, SM Sun, R Nedellec, ... Human antibodies 13 (4), 105-110, 2004 | 37 | 2004 |
Mapping neutralizing antibody epitope specificities to an HIV Env trimer in immunized and in infected rhesus macaques F Zhao, C Joyce, A Burns, B Nogal, CA Cottrell, A Ramos, T Biddle, ... Cell Reports 32 (10), 2020 | 31 | 2020 |
Passive transfer of vaccine-elicited antibodies protects against SIV in rhesus macaques G Alter, WH Yu, A Chandrashekar, EN Borducchi, K Ghneim, A Sharma, ... Cell 183 (1), 185-196. e14, 2020 | 27 | 2020 |
Effector function does not contribute to protection from virus challenge by a highly potent HIV broadly neutralizing antibody in nonhuman primates L Hangartner, D Beauparlant, E Rakasz, R Nedellec, N Hozé, ... Science translational medicine 13 (585), eabe3349, 2021 | 26 | 2021 |