DNA targeting specificity of RNA-guided Cas9 nucleases PD Hsu, DA Scott, JA Weinstein, FA Ran, S Konermann, V Agarwala, Y Li, ... Nature biotechnology 31 (9), 827-832, 2013 | 5500 | 2013 |
In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9 L Swiech, M Heidenreich, A Banerjee, N Habib, Y Li, J Trombetta, M Sur, ... Nature biotechnology 33 (1), 102-106, 2015 | 917 | 2015 |
Crystal structure of Cpf1 in complex with guide RNA and target DNA T Yamano, H Nishimasu, B Zetsche, H Hirano, IM Slaymaker, Y Li, ... Cell 165 (4), 949-962, 2016 | 725 | 2016 |
Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons N Habib, Y Li, M Heidenreich, L Swiech, I Avraham-Davidi, JJ Trombetta, ... Science 353 (6302), 925-928, 2016 | 565 | 2016 |
Crystal structure of Staphylococcus aureus Cas9 H Nishimasu, L Cong, WX Yan, FA Ran, B Zetsche, Y Li, A Kurabayashi, ... Cell 162 (5), 1113-1126, 2015 | 496 | 2015 |
BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks WX Yan, R Mirzazadeh, S Garnerone, D Scott, MW Schneider, T Kallas, ... Nature communications 8 (1), 15058, 2017 | 360 | 2017 |
Formation and optogenetic control of engineered 3D skeletal muscle bioactuators MS Sakar, D Neal, T Boudou, MA Borochin, Y Li, R Weiss, RD Kamm, ... Lab on a Chip 12 (23), 4976-4985, 2012 | 300 | 2012 |
Rapid neurogenesis through transcriptional activation in human stem cells V Busskamp, NE Lewis, P Guye, AHM Ng, SL Shipman, SM Byrne, ... Molecular systems biology 10 (11), 760, 2014 | 252 | 2014 |
CRISPR transcriptional repression devices and layered circuits in mammalian cells S Kiani, J Beal, MR Ebrahimkhani, J Huh, RN Hall, Z Xie, Y Li, R Weiss Nature methods 11 (7), 723-726, 2014 | 237 | 2014 |
A platform for rapid prototyping of synthetic gene networks in mammalian cells X Duportet, L Wroblewska, P Guye, Y Li, J Eyquem, J Rieders, T Rimchala, ... Nucleic acids research 42 (21), 13440-13451, 2014 | 164 | 2014 |
Methods, models, systems, and apparatus for identifying target sequences for Cas enzymes or CRISPR-Cas systems for target sequences and conveying results thereof F Zhang, Y Li, DA Scott, JA Weinstein, P Hsu US Patent 10,930,367, 2021 | 147 | 2021 |
Distinct subnetworks of the thalamic reticular nucleus Y Li, VG Lopez-Huerta, X Adiconis, K Levandowski, S Choi, SK Simmons, ... Nature 583 (7818), 819-824, 2020 | 138 | 2020 |
Modular construction of mammalian gene circuits using TALE transcriptional repressors Y Li, Y Jiang, H Chen, W Liao, Z Li, R Weiss, Z Xie Nature chemical biology 11 (3), 207-213, 2015 | 110 | 2015 |
Rapid, modular and reliable construction of complex mammalian gene circuits P Guye, Y Li, L Wroblewska, X Duportet, R Weiss Nucleic acids research 41 (16), e156-e156, 2013 | 109 | 2013 |
Accurate predictions of genetic circuit behavior from part characterization and modular composition N Davidsohn, J Beal, S Kiani, A Adler, F Yaman, Y Li, Z Xie, R Weiss ACS synthetic biology 4 (6), 673-681, 2015 | 75 | 2015 |
Induction of mouse totipotent stem cells by a defined chemical cocktail Y Hu, Y Yang, P Tan, Y Zhang, M Han, J Yu, X Zhang, Z Jia, D Wang, ... Nature 617 (7962), 792-797, 2023 | 58 | 2023 |
Engineered live biotherapeutics: progress and challenges Y Tan, J Shen, T Si, CL Ho, Y Li, L Dai Biotechnology Journal 15 (10), 2000155, 2020 | 22 | 2020 |
Differential excitatory vs inhibitory SCN expression at single cell level regulates brain sodium channel function in neurodevelopmental disorders J Du, S Simmons, A Brunklaus, X Adiconis, CC Hession, Z Fu, Y Li, ... European Journal of Paediatric Neurology 24, 129-133, 2020 | 21 | 2020 |
EWOD using P (VDF-TrFE) P Zhao, Y Li, X Zeng, J Zhou, Y Huang, R Liu 2009 4th IEEE International Conference on Nano/Micro Engineered and …, 2009 | 9 | 2009 |
Dual-role transcription factors stabilize intermediate expression levels J He, X Huo, G Pei, Z Jia, Y Yan, J Yu, H Qu, Y Xie, J Yuan, Y Zheng, Y Hu, ... Cell 187 (11), 2746-2766. e25, 2024 | 3 | 2024 |