Noncanonical scaffolding of Gαi and β-arrestin by G protein–coupled receptors JS Smith, TF Pack, A Inoue, C Lee, K Zheng, I Choi, DS Eiger, A Warman, ... Science 371 (6534), eaay1833, 2021 | 90 | 2021 |
GPCR systems pharmacology: a different perspective on the development of biased therapeutics DS Eiger, U Pham, J Gardner, C Hicks, S Rajagopal American Journal of Physiology-Cell Physiology 322 (5), C887-C895, 2022 | 34 | 2022 |
Biased agonism at chemokine receptors DS Eiger, N Boldizsar, CC Honeycutt, J Gardner, S Rajagopal Cellular signalling 78, 109862, 2021 | 33 | 2021 |
Location bias contributes to functionally selective responses of biased CXCR3 agonists DS Eiger, N Boldizsar, CC Honeycutt, J Gardner, S Kirchner, C Hicks, ... Nature Communications 13 (1), 5846, 2022 | 26 | 2022 |
Medical students’ reflections on the recent changes to the USMLE step exams PT Cangialosi, BC Chung, TP Thielhelm, ND Camarda, DS Eiger Academic Medicine 96 (3), 343-348, 2021 | 19 | 2021 |
Phosphorylation barcodes direct biased chemokine signaling at CXCR3 DS Eiger, JS Smith, T Shi, TM Stepniewski, CF Tsai, C Honeycutt, ... Cell chemical biology 30 (4), 362-382. e8, 2023 | 14 | 2023 |
Biased agonists of the chemokine receptor CXCR3 differentially signal through Gαi:β-arrestin complexes K Zheng, JS Smith, DS Eiger, A Warman, I Choi, CC Honeycutt, ... Science Signaling 15 (726), eabg5203, 2022 | 12 | 2022 |
Location bias: a “hidden variable” in GPCR pharmacology DS Eiger, C Hicks, J Gardner, U Pham, S Rajagopal Bioessays 45 (11), 2300123, 2023 | 9 | 2023 |
The Right to Write: Who ‘Owns’ the Case Report? A Agrawal, D Eiger, D Jain, R Allman, G Eiger European journal of case reports in internal medicine 6 (1), 2019 | 9 | 2019 |
GPCR kinases differentially modulate biased signaling downstream of CXCR3 depending on their subcellular localization J Gardner, DS Eiger, C Hicks, I Choi, U Pham, A Chundi, O Namjoshi, ... Science signaling 17 (823), eadd9139, 2024 | 5 | 2024 |
Factors and outcomes associated with improved left ventricular systolic function in patients with cardiomyopathy DS Eiger, LYT Inoue, Q Li, G Bardy, K Lee, J Poole, D Mark, Z Samad, ... Cardiology Journal 29 (6), 978-984, 2022 | 2 | 2022 |
Mass spectrometry-based proteomics for analysis of hydrophilic phosphopeptides CF Tsai, JS Smith, DS Eiger, K Martin, T Liu, RD Smith, T Shi, ... Shotgun Proteomics: Methods and Protocols, 247-257, 2021 | 2 | 2021 |
Subcellular localization of GPCR kinases differentially modulate biased signaling at CXCR3 J Gardner, DS Eiger, C Hicks, I Choi, U Pham, S Rajagopal bioRxiv, 2022.07. 11.499601, 2022 | 1 | 2022 |
577 Chemokine signaling at CXCR3 is not redundant and encoded through receptor phosphorylation ensembles J Smith, DS Eiger, T Shi, J Jacobs, S Rajagopal, A Kruse Journal of Investigative Dermatology 144 (8), S101, 2024 | | 2024 |
ACKR3 Proximity Labeling Identifies Novel G protein-and β-arrestin-independent GPCR Interacting Proteins C Hicks, J Gardner, DS Eiger, ND Camarda, U Pham, S Dhar, ... bioRxiv, 2024 | | 2024 |
Mechanisms of Biased Signaling at the Chemokine Receptor CXCR3 DS Eiger | | 2023 |
582 CXCL9, CXLC10, and CXCL11 differentially form CXCR3-regulated G protein: β-arrestin signaling complexes JS Smith, K Zheng, D Eiger, T Pack, S Rajagopal Journal of Investigative Dermatology 142 (8), S99, 2022 | | 2022 |
Advances in GPCRs: Structure, Mechanisms, Disease, and Pharmacology: GPCR systems pharmacology: a different perspective on the development of biased therapeutics DS Eiger, U Pham, J Gardner, C Hicks, S Rajagopal American Journal of Physiology-Cell Physiology 322 (5), C887, 2022 | | 2022 |
Phosphorylation barcode ensembles encoded by biased CXCR3 agonists direct non‐redundant chemokine signaling DS Eiger, J Smith, T Shi, TM Stepniewski, C Honeycutt, N Boldizsar, ... The FASEB Journal 36, 2022 | | 2022 |
Location Bias of G Protein‐Coupled Receptor Kinases Promotes Biased Signaling at CXCR3 CN Hicks, D Eiger, J Gardner, N Boldizsar, C Honeycutt, I Choi, ... The FASEB Journal 36, 2022 | | 2022 |