Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer’s disease SF Lau, H Cao, AKY Fu, NY Ip Proceedings of the National Academy of Sciences 117 (41), 25800-25809, 2020 | 326 | 2020 |
IL-33-PU. 1 transcriptome reprogramming drives functional state transition and clearance activity of microglia in Alzheimer’s disease SF Lau, C Chen, WY Fu, JY Qu, TH Cheung, AKY Fu, NY Ip Cell Reports 31 (3), 107530, 2020 | 89 | 2020 |
Cytokine signaling convergence regulates the microglial state transition in Alzheimer’s disease SF Lau, AKY Fu, NY Ip Cellular and Molecular Life Sciences 78, 4703-4712, 2021 | 32 | 2021 |
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease Y Jiang, X Zhou, HY Wong, L Ouyang, FCF Ip, VMN Chau, SF Lau, W Wu, ... Nature aging 2 (7), 616-634, 2022 | 25 | 2022 |
The VCAM1–ApoE pathway directs microglial chemotaxis and alleviates Alzheimer’s disease pathology SF Lau, W Wu, HY Wong, L Ouyang, Y Qiao, J Xu, JHY Lau, C Wong, ... Nature Aging 3 (10), 1219-1236, 2023 | 22 | 2023 |
Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer’s disease transgenic mouse model JKY Lau, M Tian, Y Shen, SF Lau, WY Fu, AKY Fu, NY Ip Scientific reports 11 (1), 4359, 2021 | 18 | 2021 |
Rhynchophylline Administration ameliorates amyloid-β pathology and inflammation in an Alzheimer’s disease transgenic mouse model WY Fu, KW Hung, SF Lau, B Butt, VWH Yuen, G Fu, IC Chan, FCF Ip, ... ACS Chemical Neuroscience 12 (22), 4249-4256, 2021 | 17 | 2021 |
High-resolution two-photon transcranial imaging of brain using direct wavefront sensing C Chen, Z Qin, S He, S Liu, SF Lau, W Wu, D Zhu, NY Ip, JY Qu Photonics Research 9 (6), 1144-1156, 2021 | 17 | 2021 |
Receptor-ligand interaction controls microglial chemotaxis and amelioration of Alzheimer's disease pathology SF Lau, AKY Fu, NY Ip Journal of neurochemistry, 2023 | 11 | 2023 |
Quantitative in vivo assessment of amyloid-beta phagocytic capacity in an Alzheimer’s disease mouse model SF Lau, W Wu, H Seo, AKY Fu, NY Ip STAR protocols 2 (1), 100265, 2021 | 11 | 2021 |
α2-Chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis YT Su, SF Lau, JPK Ip, K Cheung, THT Cheung, AKY Fu, NY Ip Proceedings of the National Academy of Sciences 116 (27), 13651-13660, 2019 | 11 | 2019 |
An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE‐ε4 in Alzheimer’s disease Y JIANG, X Zhou, HY Wong, O Li, FCF Ip, VMN Chau, SF Lau, W Wu, ... Alzheimer's & Dementia 19, e064428, 2023 | | 2023 |
IL-33-dependent transcriptome reprogramming drives functional state transition and clearance activity of microglia in Alzheimer’s disease SF Lau, C Chen, WY Fu, J Qu, HT Cheung, KY Fu, NYY Ip | | 2019 |