| Expanding the enzyme universe: accessing non‐natural reactions by mechanism‐guided directed evolution H Renata, ZJ Wang, FH Arnold Angewandte Chemie International Edition 54 (11), 3351-3367, 2015 | 542 | 2015 |
| Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization RK Zhang, K Chen, X Huang, L Wohlschlager, H Renata, FH Arnold Nature 565 (7737), 67-72, 2019 | 285 | 2019 |
| Improved cyclopropanation activity of histidine‐ligated cytochrome P450 enables the enantioselective formal synthesis of levomilnacipran ZJ Wang, H Renata, NE Peck, CC Farwell, PS Coelho, FH Arnold Angewandte Chemie 126 (26), 6928-6931, 2014 | 221 | 2014 |
| Cytochrome P450-catalyzed insertion of carbenoids into N–H bonds Z JaneáWang Chemical science 5 (2), 598-601, 2014 | 195 | 2014 |
| Strategic redox relay enables a scalable synthesis of ouabagenin, a bioactive cardenolide H Renata, Q Zhou, PS Baran Science 339 (6115), 59-63, 2013 | 173 | 2013 |
| Development of a concise synthesis of ouabagenin and hydroxylated corticosteroid analogues H Renata, Q Zhou, G Dunstl, J Felding, RR Merchant, CH Yeh, PS Baran Journal of the American Chemical Society 137 (3), 1330-1340, 2015 | 131 | 2015 |
| Divergent synthesis of complex diterpenes through a hybrid oxidative approach X Zhang, E King-Smith, LB Dong, LC Yang, JD Rudolf, B Shen, H Renata Science 369 (6505), 799-806, 2020 | 116 | 2020 |
| Remote C–H hydroxylation by an α-ketoglutarate-dependent dioxygenase enables efficient chemoenzymatic synthesis of manzacidin C and proline analogs CR Zwick III, H Renata Journal of the American Chemical Society 140 (3), 1165-1169, 2018 | 107 | 2018 |
| Merging chemoenzymatic and radical-based retrosynthetic logic for rapid and modular synthesis of oxidized meroterpenoids J Li, F Li, E King-Smith, H Renata Nature chemistry 12 (2), 173-179, 2020 | 89 | 2020 |
| Highly stereoselective biocatalytic synthesis of key cyclopropane intermediate to ticagrelor KE Hernandez, H Renata, RD Lewis, SBJ Kan, C Zhang, J Forte, ... ACS catalysis 6 (11), 7810-7813, 2016 | 87 | 2016 |
| Total synthesis of tambromycin by combining chemocatalytic and biocatalytic C− H functionalization X Zhang, E King‐Smith, H Renata Angewandte Chemie International Edition 57 (18), 5037-5041, 2018 | 80 | 2018 |
| Identification of mechanism-based inactivation in P450-catalyzed cyclopropanation facilitates engineering of improved enzymes H Renata, RD Lewis, MJ Sweredoski, A Moradian, S Hess, ZJ Wang, ... Journal of the American Chemical Society 138 (38), 12527-12533, 2016 | 73 | 2016 |
| Asymmetric chemoenzymatic synthesis of (−)‐podophyllotoxin and related aryltetralin lignans J Li, X Zhang, H Renata Angewandte Chemie International Edition 58 (34), 11657-11660, 2019 | 69 | 2019 |
| Directed evolution of a bright near-infrared fluorescent rhodopsin using a synthetic chromophore L Herwig, AJ Rice, CN Bedbrook, RK Zhang, A Lignell, JKB Cahn, ... Cell chemical biology 24 (3), 415-425, 2017 | 67 | 2017 |
| P450-catalyzed asymmetric cyclopropanation of electron-deficient olefins under aerobic conditions Z JaneáWang Catalysis science & technology 4 (10), 3640-3643, 2014 | 67 | 2014 |
| Recent advances in the chemoenzymatic synthesis of bioactive natural products J Li, A Amatuni, H Renata Current opinion in chemical biology 55, 111-118, 2020 | 64 | 2020 |
| Ausdehnung des Enzym‐Universums: Zugang zu nicht‐natürlichen Reaktionen durch mechanismusgeleitete, gerichtete Evolution H Renata, ZJ Wang, FH Arnold Angewandte Chemie 127 (11), 3408-3426, 2015 | 63 | 2015 |
| Harnessing the biocatalytic potential of iron-and α-ketoglutarate-dependent dioxygenases in natural product total synthesis CR Zwick, H Renata Natural Product Reports 37 (8), 1065-1079, 2020 | 59 | 2020 |
| Enzymatic CH functionalizations for natural product synthesis F Li, X Zhang, H Renata Current opinion in chemical biology 49, 25-32, 2019 | 53 | 2019 |
| Applications of oxygenases in the chemoenzymatic total synthesis of complex natural products E King-Smith, CR Zwick III, H Renata Biochemistry 57 (4), 403-412, 2018 | 50 | 2018 |
