MDSC targeting with Gemtuzumab ozogamicin restores T cell immunity and immunotherapy against cancers L Fultang, S Panetti, M Ng, P Collins, S Graef, N Rizkalla, S Booth, ... EBioMedicine 47, 235-246, 2019 | 145 | 2019 |
Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity L Fultang, S Booth, O Yogev, B Martins da Costa, V Tubb, S Panetti, ... Blood, The Journal of the American Society of Hematology 136 (10), 1155-1160, 2020 | 116 | 2020 |
Molecular basis and current strategies of therapeutic arginine depletion for cancer F Livingstone, V Ashley, DS Carmela, M Francis International Journal of Cancer, 2016 | 103 | 2016 |
Targeting the arginine metabolic brake enhances immunotherapy for leukaemia F Mussai, R Wheat, E Sarrou, S Booth, V Stavrou, L Fultang, T Perry, ... International journal of cancer 145 (8), 2201-2208, 2019 | 69 | 2019 |
Macrophage-derived IL1β and TNFα regulate arginine metabolism in neuroblastoma L Fultang, LD Gamble, L Gneo, AM Berry, SA Egan, F De Bie, O Yogev, ... Cancer research 79 (3), 611-624, 2019 | 56 | 2019 |
Engineering amino acid uptake or catabolism promotes CAR T-cell adaption to the tumor environment S Panetti, N McJannett, L Fultang, S Booth, L Gneo, U Scarpa, C Smith, ... Blood Advances 7 (9), 1754-1761, 2023 | 18 | 2023 |
Targeting amino acid metabolic vulnerabilities in myeloid malignancies L Fultang, L Gneo, C De Santo, FJ Mussai Frontiers in Oncology 11, 674720, 2021 | 16 | 2021 |
G‐CSF induces CD15+ CD14+ cells from granulocytes early in the physiological environment of pregnancy and the cancer immunosuppressive microenvironment E Maneta, L Fultang, J Taylor, M Pugh, W Jenkinson, G Anderson, ... Clinical & translational immunology 11 (5), e1395, 2022 | 10 | 2022 |
Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment V Stavrou, L Fultang, S Booth, D De Simone, A Bartnik, U Scarpa, L Gneo, ... Cancer Immunology, Immunotherapy 72 (3), 543-560, 2023 | 5 | 2023 |
PARC: a phase I/II study evaluating the safety and activity of pegylated recombinant human arginase BCT-100 in relapsed/refractory cancers of children and young adults N Fenwick, R Weston, K Wheatley, J Hodgson, L Marshall, M Elliott, ... Frontiers in Oncology 14, 1296576, 2024 | 1 | 2024 |
Evaluating the use of chimeric antigen receptor (CAR) to redirect blood monocyte derived macrophages against neuroblastoma L Fultang, F De Santo, Carmela, Mussai British Society for Immunology Congress, Edignburgh 2021, P041, 2021 | | 2021 |
Stress induced transcriptional regulation of the glycine transporter type 1A (GlyT-1A/SLC6A9) in human intestinal epithelia LKF Fultang Newcastle University, 2015 | | 2015 |
Expression of the glycine transporter type 1 (GlyT‐1A) is upregulated by ATF‐4 following physiological stress in human intestinal epithelial cells (1109.14) L Fultang, A Howard, B Hirst The FASEB Journal 28, 1109.14, 2014 | | 2014 |
Macrophage-derived IL-1? and TNF-? regulate arginine metabolism in neuroblastoma SA Burchill, DS Ziegler, HC Etchevers, MD Norris, PN Cheng, ... Cancer Research 79 (3), 0 | | |