| From DARPins to LoopDARPins: novel LoopDARPin design allows the selection of low picomolar binders in a single round of ribosome display J Schilling, J Schöppe, A Plückthun Journal of molecular biology 426 (3), 691-721, 2014 | 126 | 2014 |
| Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter M Hohl, LM Hürlimann, S Böhm, J Schöppe, MG Grütter, E Bordignon, ... Proceedings of the National Academy of Sciences 111 (30), 11025-11030, 2014 | 124 | 2014 |
| High-resolution crystal structure of parathyroid hormone 1 receptor in complex with a peptide agonist J Ehrenmann, J Schöppe, C Klenk, M Rappas, L Kummer, AS Doré, ... Nature structural & molecular biology 25 (12), 1086-1092, 2018 | 104 | 2018 |
| Crystal structure of the human oxytocin receptor Y Waltenspühl, J Schöppe, J Ehrenmann, L Kummer, A Plückthun Science Advances 6 (29), eabb5419, 2020 | 81 | 2020 |
| Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists J Schöppe, J Ehrenmann, C Klenk, P Rucktooa, M Schütz, AS Doré, ... Nature communications 10 (1), 17, 2019 | 79 | 2019 |
| Directed evolution of G protein-coupled receptors in yeast for higher functional production in eukaryotic expression hosts M Schütz, J Schöppe, E Sedlák, M Hillenbrand, G Nagy-Davidescu, ... Scientific reports 6 (1), 21508, 2016 | 69 | 2016 |
| Comprehensive analysis of heterotrimeric G-protein complex diversity and their interactions with GPCRs in solution M Hillenbrand, C Schori, J Schöppe, A Plückthun Proceedings of the National Academy of Sciences 112 (11), E1181-E1190, 2015 | 64 | 2015 |
| Structures of neurokinin 1 receptor in complex with Gq and Gs proteins reveal substance P binding mode and unique activation features C Thom, J Ehrenmann, S Vacca, Y Waltenspühl, J Schöppe, O Medalia, ... Science advances 7 (50), eabk2872, 2021 | 35 | 2021 |
| Phase behavior of a designed cyclopropyl analogue of monoolein: implications for low‐temperature membrane protein crystallization L Salvati Manni, A Zabara, YM Osornio, J Schöppe, A Batyuk, A Plückthun, ... Angewandte Chemie International Edition 54 (3), 1027-1031, 2015 | 34 | 2015 |
| Generation of fluorogen-activating designed ankyrin repeat proteins (FADAs) as versatile sensor tools M Schütz, A Batyuk, C Klenk, L Kummer, S De Picciotto, B Gülbakan, ... Journal of molecular biology 428 (6), 1272-1289, 2016 | 26 | 2016 |
| Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W J Schilling, J Schöppe, E Sauer, A Plückthun Journal of molecular biology 426 (12), 2346-2362, 2014 | 15 | 2014 |
| Universal platform for the generation of thermostabilized GPCRs that crystallize in LCP J Schöppe, J Ehrenmann, Y Waltenspühl, A Plückthun Nature Protocols 17 (3), 698-726, 2022 | 5 | 2022 |
| New views into class B GPCRs from the crystal structure of PTH1R J Ehrenmann, J Schöppe, C Klenk, A Plückthun The FEBS journal 286 (24), 4852-4860, 2019 | 5 | 2019 |
| Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410 S Remm, D De Vecchis, J Schöppe, CAJ Hutter, I Gonda, M Hohl, ... Nature Communications 14 (1), 6449, 2023 | 4 | 2023 |
| Protein engineering and structural biology of G protein-coupled receptors J Schöppe University of Zurich, 2019 | | 2019 |
| Directed evolution of human parathyroid hormone 1 receptor for improved expression and stability C Klenk, J Ehrenmann, J Schoeppe, L Kummer, M Schuetz, A Plueckthun NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 389 (SUPPL 1), 16-17, 2016 | | 2016 |
