HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology C Gille, C Bölling, A Hoppe, S Bulik, S Hoffmann, K Hübner, A Karlstädt, ... Molecular systems biology 6 (1), 411, 2010 | 355 | 2010 |
MEMOTE for standardized genome-scale metabolic model testing C Lieven, ME Beber, BG Olivier, FT Bergmann, M Ataman, P Babaei, ... Nature biotechnology 38 (3), 272-276, 2020 | 354 | 2020 |
Quantifying the contribution of the liver to glucose homeostasis: a detailed kinetic model of human hepatic glucose metabolism M König, S Bulik, HG Holzhütter PLoS computational biology 8 (6), e1002577, 2012 | 252 | 2012 |
SBML Level 3: an extensible format for the exchange and reuse of biological models SM Keating, D Waltemath, M König, F Zhang, A Dräger, C Chaouiya, ... Molecular systems biology 16 (8), e9110, 2020 | 212 | 2020 |
libRoadRunner: a high performance SBML simulation and analysis library ET Somogyi, JM Bouteiller, JA Glazier, M König, JK Medley, MH Swat, ... Bioinformatics 31 (20), 3315-3321, 2015 | 151 | 2015 |
Tellurium: an extensible python-based modeling environment for systems and synthetic biology K Choi, JK Medley, M König, K Stocking, L Smith, S Gu, HM Sauro Biosystems 171, 74-79, 2018 | 139 | 2018 |
The systems biology markup language (SBML): language specification for level 3 version 2 core release 2 M Hucka, FT Bergmann, C Chaouiya, A Dräger, S Hoops, SM Keating, ... Journal of integrative bioinformatics 16 (2), 20190021, 2019 | 105 | 2019 |
Modeling function–perfusion behavior in liver lobules including tissue, blood, glucose, lactate and glycogen by use of a coupled two-scale PDE–ODE approach T Ricken, D Werner, HG Holzhütter, M König, U Dahmen, O Dirsch Biomechanics and modeling in mechanobiology 14, 515-536, 2015 | 96 | 2015 |
Enzymatic features of the glucose metabolism in tumor cells A Herling, M König, S Bulik, HG Holzhütter The FEBS journal 278 (14), 2436-2459, 2011 | 85 | 2011 |
Harmonizing semantic annotations for computational models in biology ML Neal, M König, D Nickerson, G Mısırlı, R Kalbasi, A Dräger, K Atalag, ... Briefings in bioinformatics 20 (2), 540-550, 2019 | 72 | 2019 |
Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice K Abshagen, M König, A Hoppe, I Müller, M Ebert, H Weng, HG Holzhütter, ... BMC systems biology 9, 1-21, 2015 | 70 | 2015 |
Toward community standards and software for whole-cell modeling D Waltemath, JR Karr, FT Bergmann, V Chelliah, M Hucka, M Krantz, ... IEEE Transactions on Biomedical Engineering 63 (10), 2007-2014, 2016 | 64 | 2016 |
Tellurium notebooks—an environment for reproducible dynamical modeling in systems biology JK Medley, K Choi, M König, L Smith, S Gu, J Hellerstein, SC Sealfon, ... PLoS computational biology 14 (6), e1006220, 2018 | 62 | 2018 |
HEPATOKIN1 is a biochemistry-based model of liver metabolism for applications in medicine and pharmacology N Berndt, S Bulik, I Wallach, T Wünsch, M König, M Stockmann, ... Nature communications 9 (1), 2386, 2018 | 59 | 2018 |
CySBML: a Cytoscape plugin for SBML M König, A Dräger, HG Holzhütter Bioinformatics 28 (18), 2402-2403, 2012 | 57 | 2012 |
Pharmacokinetics of caffeine: A systematic analysis of reported data for application in metabolic phenotyping and liver function testing J Grzegorzewski, F Bartsch, A Köller, M König Frontiers in pharmacology 12, 752826, 2022 | 48 | 2022 |
Computational modeling in liver surgery B Christ, U Dahmen, KH Herrmann, M König, JR Reichenbach, T Ricken, ... Frontiers in Physiology 8, 906, 2017 | 45 | 2017 |
PK-DB: pharmacokinetics database for individualized and stratified computational modeling J Grzegorzewski, J Brandhorst, K Green, D Eleftheriadou, Y Duport, ... Nucleic acids research 49 (D1), D1358-D1364, 2021 | 37 | 2021 |
The first 10 years of the international coordination network for standards in systems and synthetic biology (COMBINE) D Waltemath, M Golebiewski, ML Blinov, P Gleeson, H Hermjakob, ... Journal of integrative bioinformatics 17 (2-3), 20200005, 2020 | 33 | 2020 |
Specifications of standards in systems and synthetic biology: status and developments in 2020 F Schreiber, B Sommer, T Czauderna, M Golebiewski, TE Gorochowski, ... Journal of integrative bioinformatics 17 (2-3), 20200022, 2020 | 32 | 2020 |