The energetics and physiological impact of cohesin extrusion L Vian, A Pękowska, SSP Rao, KR Kieffer-Kwon, S Jung, L Baranello, ... Cell 173 (5), 1165-1178. e20, 2018 | 546 | 2018 |
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development A Ortega-Molina, IW Boss, A Canela, H Pan, Y Jiang, C Zhao, M Jiang, ... Nature medicine 21 (10), 1199-1208, 2015 | 437 | 2015 |
The longest telomeres: a general signature of adult stem cell compartments I Flores, A Canela, E Vera, A Tejera, G Cotsarelis, MA Blasco Genes & development 22 (5), 654-667, 2008 | 418 | 2008 |
High-throughput telomere length quantification by FISH and its application to human population studies A Canela, E Vera, P Klatt, MA Blasco Proceedings of the National Academy of Sciences 104 (13), 5300-5305, 2007 | 409 | 2007 |
Genome organization drives chromosome fragility A Canela, Y Maman, S Jung, N Wong, E Callen, A Day, KR Kieffer-Kwon, ... Cell 170 (3), 507-521. e18, 2017 | 383 | 2017 |
DNA breaks and end resection measured genome-wide by end sequencing A Canela, S Sridharan, N Sciascia, A Tubbs, P Meltzer, BP Sleckman, ... Molecular cell 63 (5), 898-911, 2016 | 251 | 2016 |
DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier MA Santos, RB Faryabi, AV Ergen, AM Day, A Malhowski, A Canela, ... Nature 514 (7520), 107-111, 2014 | 211 | 2014 |
Dual roles of poly (dA: dT) tracts in replication initiation and fork collapse A Tubbs, S Sridharan, N van Wietmarschen, Y Maman, E Callen, ... Cell 174 (5), 1127-1142. e19, 2018 | 186 | 2018 |
Topoisomerase II-induced chromosome breakage and translocation is determined by chromosome architecture and transcriptional activity A Canela, Y Maman, NH Shar-yin, G Wutz, W Tang, G Zagnoli-Vieira, ... Molecular cell 75 (2), 252-266. e8, 2019 | 171 | 2019 |
Neuronal enhancers are hotspots for DNA single-strand break repair W Wu, SE Hill, WJ Nathan, J Paiano, E Callen, D Wang, K Shinoda, ... Nature 593 (7859), 440-444, 2021 | 157 | 2021 |
Epigenetic regulation of telomeres in human cancer E Vera, A Canela, MF Fraga, M Esteller, MA Blasco Oncogene 27 (54), 6817-6833, 2008 | 144 | 2008 |
Centromere mitotic recombination in mammalian cells I Jaco, A Canela, E Vera, MA Blasco The Journal of cell biology 181 (6), 885, 2008 | 140 | 2008 |
Massive telomere loss is an early event of DNA damage-induced apoptosis R Ramırez, J Carracedo, R Jiménez, A Canela, E Herrera, P Aljama, ... Journal of Biological Chemistry 278 (2), 836-842, 2003 | 124 | 2003 |
Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice A Canela, J Martín-Caballero, JM Flores, MA Blasco Molecular and cellular biology, 2004 | 116 | 2004 |
53BP1 enforces distinct pre-and post-resection blocks on homologous recombination E Callen, D Zong, W Wu, N Wong, A Stanlie, M Ishikawa, R Pavani, ... Molecular cell 77 (1), 26-38. e7, 2020 | 108 | 2020 |
Telomere length analysis A Canela, P Klatt, MA Blasco Biological Aging: Methods and Protocols, 45-72, 2007 | 55 | 2007 |
Telomerase deficiency promotes oxidative stress by reducing catalase activity G Pérez-Rivero, MP Ruiz-Torres, ML Díez-Marqués, A Canela, ... Free Radical Biology and Medicine 45 (9), 1243-1251, 2008 | 41 | 2008 |
END-seq: an unbiased, high-resolution, and genome-wide approach to map DNA double-strand breaks and resection in human cells N Wong, S John, A Nussenzweig, A Canela Homologous Recombination: Methods and Protocols, 9-31, 2021 | 39 | 2021 |
Accumulation of cells with short telomeres is associated with impaired zinc homeostasis and inflammation in old hypertensive participants C Cipriano, S Tesei, M Malavolta, R Giacconi, E Muti, L Costarelli, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2009 | 37 | 2009 |
Single-cell telomere-length quantification couples telomere length to meristem activity and stem cell development in Arabidopsis MP González-García, I Pavelescu, A Canela, X Sevillano, KA Leehy, ... Cell reports 11 (6), 977-989, 2015 | 29 | 2015 |