| Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ... Nature 475 (7354), 106-109, 2011 | 2369 | 2011 |
| Aneuploidy drives genomic instability in yeast JM Sheltzer, HM Blank, SJ Pfau, Y Tange, BM George, TJ Humpton, ... Science 333 (6045), 1026-1030, 2011 | 451 | 2011 |
| A role for p53 in the adaptation to glutamine starvation through the expression of SLC1A3 M Tajan, AK Hock, J Blagih, NA Robertson, CF Labuschagne, F Kruiswijk, ... Cell metabolism 28 (5), 721-736. e6, 2018 | 225 | 2018 |
| Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop TG Oliver, E Meylan, GP Chang, W Xue, JR Burke, TJ Humpton, ... Molecular cell 43 (1), 57-71, 2011 | 176 | 2011 |
| Oncogenic KRAS induces NIX-mediated mitophagy to promote pancreatic cancer TJ Humpton, B Alagesan, GM DeNicola, D Lu, GN Yordanov, ... Cancer discovery 9 (9), 1268-1287, 2019 | 152 | 2019 |
| Regulation of cellular metabolism and hypoxia by p53 TJ Humpton, KH Vousden Cold Spring Harbor perspectives in medicine 6 (7), a026146, 2016 | 139 | 2016 |
| p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant TJ Humpton, AK Hock, ODK Maddocks, KH Vousden Cancer & metabolism 6, 1-12, 2018 | 49 | 2018 |
| The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance DR Caswell, P Gui, MK Mayekar, EK Law, O Pich, C Bailey, J Boumelha, ... Nature Genetics 56 (1), 60-73, 2024 | 25 | 2024 |
| p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl4 TJ Humpton, H Hall, C Kiourtis, C Nixon, W Clark, A Hedley, R Shaw, ... Cell Death & Differentiation 29 (3), 514-526, 2022 | 23 | 2022 |
| Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo AK Hock, EC Cheung, TJ Humpton, T Monteverde, V Paulus-Hock, P Lee, ... Scientific Reports 7 (1), 1837, 2017 | 22 | 2017 |
| Taking up the reins of power: metabolic functions of p53 T Humpton, KH Vousden Journal of molecular cell biology 11 (7), 610-614, 2019 | 18 | 2019 |
| Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice TJ Humpton, K Nomura, J Weber, HM Magnussen, AK Hock, C Nixon, ... Genes & development 35 (1-2), 117-132, 2021 | 9 | 2021 |
| A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo TJ Humpton, AK Hock, C Kiourtis, M De Donatis, F Fercoq, C Nixon, ... Science signaling 15 (720), eabd9099, 2022 | 6 | 2022 |
| The role of APOBEC3B in lung tumour evolution and targeted therapy resistance DR Caswell, MK Mayekar, P Gui, EK Law, NI Vokes, CM Ruiz, M Dietzen, ... bioRxiv, 2020.12. 18.423280, 2020 | 2 | 2020 |
| p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis CI Wittke, EC Cheung, D Athineos, N Clements, L Butler, M Hughes, ... bioRxiv, 2024.05. 20.594983, 2024 | | 2024 |
| Oncogenic KRAS stimulates the clearance of functional mitochondria to promote proliferation during glucose deprivation TJ Humpton University of Cambridge, 2014 | | 2014 |
| Nix-mediated mitophagy promotes pancreatic cancer TJ Humpton, B Alagesan, GM DeNicola, D Lu, GN Yordanov, ... | | |
