Single-cell multi-omics analysis of the immune response in COVID-19 E Stephenson, G Reynolds, RA Botting, FJ Calero-Nieto, MD Morgan, ... Nature medicine 27 (5), 904-916, 2021 | 548* | 2021 |
N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis RR Edupuganti, S Geiger, RGH Lindeboom, H Shi, PJ Hsu, Z Lu, ... Nature structural & molecular biology 24 (10), 870-878, 2017 | 523 | 2017 |
The rules and impact of nonsense-mediated mRNA decay in human cancers RGH Lindeboom, F Supek, B Lehner Nature genetics 48 (10), 1112-1118, 2016 | 437 | 2016 |
Local and systemic responses to SARS-CoV-2 infection in children and adults M Yoshida, KB Worlock, N Huang, RGH Lindeboom, CR Butler, ... Nature 602 (7896), 321-327, 2022 | 247 | 2022 |
The impact of nonsense-mediated mRNA decay on genetic disease, gene editing and cancer immunotherapy RGH Lindeboom, M Vermeulen, B Lehner, F Supek Nature genetics 51 (11), 1645-1651, 2019 | 206 | 2019 |
Probing the tumor suppressor function of BAP1 in CRISPR-engineered human liver organoids B Artegiani, L van Voorthuijsen, RGH Lindeboom, D Seinstra, I Heo, ... Cell Stem Cell 24 (6), 927-943. e6, 2019 | 159 | 2019 |
To NMD or not to NMD: nonsense-mediated mRNA decay in cancer and other genetic diseases F Supek, B Lehner, RGH Lindeboom Trends in Genetics 37 (7), 657-668, 2021 | 157 | 2021 |
Single-molecule imaging uncovers rules governing nonsense-mediated mRNA decay TA Hoek, D Khuperkar, RGH Lindeboom, S Sonneveld, BMP Verhagen, ... Molecular cell 75 (2), 324-339. e11, 2019 | 134 | 2019 |
Integrative multi‐omics analysis of intestinal organoid differentiation RGH Lindeboom, L van Voorthuijsen, KC Oost, MJ Rodríguez‐Colman, ... Molecular systems biology 14 (6), e8227, 2018 | 123 | 2018 |
ZMYND8 co-localizes with NuRD on target genes and regulates poly (ADP-ribose)-dependent recruitment of GATAD2A/NuRD to sites of DNA damage CG Spruijt, MS Luijsterburg, R Menafra, RGH Lindeboom, PWTC Jansen, ... Cell reports 17 (3), 783-798, 2016 | 114 | 2016 |
Towards a human cell atlas: taking notes from the past RGH Lindeboom, A Regev, SA Teichmann Trends in Genetics 37 (7), 625-630, 2021 | 71 | 2021 |
Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs AH Smits, RGH Lindeboom, M Perino, SJ van Heeringen, GJC Veenstra, ... Nucleic acids research 42 (15), 9880-9891, 2014 | 71 | 2014 |
A spatially resolved atlas of the human lung characterizes a gland-associated immune niche E Madissoon, AJ Oliver, V Kleshchevnikov, A Wilbrey-Clark, K Polanski, ... Nature Genetics 55 (1), 66-77, 2023 | 58 | 2023 |
Quantification of proteins and histone marks in Drosophila embryos reveals stoichiometric relationships impacting chromatin regulation J Bonnet, RGH Lindeboom, D Pokrovsky, G Stricker, MH Celik, ... Developmental cell 51 (5), 632-644. e6, 2019 | 55 | 2019 |
Hydroxychloroquine inhibits the trained innate immune response to interferons N Rother, C Yanginlar, RGH Lindeboom, S Bekkering, MMT van Leent, ... Cell Reports Medicine 1 (9), 2020 | 39* | 2020 |
Recruitment of the mammalian histone-modifying EMSY complex to target genes is regulated by ZNF131 RA Varier, EC de Santa Pau, P Van Der Groep, RGH Lindeboom, ... Journal of Biological Chemistry 291 (14), 7313-7324, 2016 | 39 | 2016 |
RNF 43 truncations trap CK 1 to drive niche‐independent self‐renewal in cancer M Spit, N Fenderico, I Jordens, T Radaszkiewicz, RGH Lindeboom, ... The EMBO Journal 39 (18), e103932, 2020 | 38 | 2020 |
Liver colonization by colorectal cancer metastases requires YAP-controlled plasticity at the micrometastatic stage MC Heinz, NA Peters, KC Oost, RGH Lindeboom, L van Voorthuijsen, ... Cancer research 82 (10), 1953-1968, 2022 | 37 | 2022 |
Specific labeling of stem cell activity in human colorectal organoids using an ASCL2-responsive minigene KC Oost, L van Voorthuijsen, A Fumagalli, RGH Lindeboom, J Sprangers, ... Cell reports 22 (6), 1600-1614, 2018 | 30 | 2018 |
NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells SL Kloet, ID Karemaker, L van Voorthuijsen, RGH Lindeboom, ... Nature communications 9 (1), 4588, 2018 | 29 | 2018 |