Astrocyte-Derived Estrogen Regulates Reactive Astrogliosis and is Neuroprotective Following Ischemic Brain Injury J Wang, GR Sareddy, Y Lu, UP Pratap, F Tang, KM Greene, PL Meyre, ... Journal of Neuroscience 40 (50), 9751-9771, 2020 | 91 | 2020 |
Neuron-derived estrogen is critical for astrocyte activation and neuroprotection of the ischemic brain Y Lu, GR Sareddy, J Wang, Q Zhang, FL Tang, UP Pratap, RR Tekmal, ... Journal of Neuroscience 40 (38), 7355-7374, 2020 | 84 | 2020 |
Brain-derived estrogen and neural function DW Brann, Y Lu, J Wang, Q Zhang, R Thakkar, GR Sareddy, UP Pratap, ... Neuroscience & Biobehavioral Reviews 132, 793-817, 2022 | 80 | 2022 |
EC359: A first-in-class small-molecule inhibitor for targeting oncogenic LIFR signaling in triple-negative breast cancer S Viswanadhapalli, Y Luo, GR Sareddy, B Santhamma, M Zhou, M Li, ... Molecular cancer therapeutics 18 (8), 1341-1354, 2019 | 57 | 2019 |
Estrogen-induced neuroprotective and anti-inflammatory effects are dependent on the brain areas of middle-aged female rats UP Pratap, A Patil, HR Sharma, L Hima, R Chockalingam, MM Hariharan, ... Brain research bulletin 124, 238-253, 2016 | 42 | 2016 |
Estrogen upregulates inflammatory signals through NF-κB, IFN-γ, and nitric oxide via Akt/mTOR pathway in the lymph node lymphocytes of middle-aged female rats UP Pratap, HR Sharma, A Mohanty, P Kale, S Gopinath, L Hima, ... International immunopharmacology 29 (2), 591-598, 2015 | 38 | 2015 |
KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer M Zhou, PP Venkata, S Viswanadhapalli, B Palacios, S Alejo, Y Chen, ... Breast cancer research and treatment 185, 343-357, 2021 | 27 | 2021 |
Estrogen modulates β2-adrenoceptor-induced cell-mediated and inflammatory immune responses through ER-α involving distinct intracellular signaling pathways, antioxidant enzymes … HP Priyanka, RV Singh, UP Pratap, S ThyagaRajan Cellular immunology 292 (1-2), 1-8, 2014 | 24 | 2014 |
Estrogen-induced neuroimmunomodulation as facilitator of and barrier to reproductive aging in brain and lymphoid organs S ThyagaRajan, L Hima, UP Pratap, HP Priyanka, R Vasantharekha Journal of chemical neuroanatomy 95, 6-12, 2019 | 22 | 2019 |
Neuron-Derived Estrogen—A Key Neuromodulator in Synaptic Function and Memory DW Brann, Y Lu, J Wang, GR Sareddy, UP Pratap, Q Zhang, RR Tekmal, ... International Journal of Molecular Sciences 22 (24), 13242, 2021 | 21 | 2021 |
Estrogen modulates neural–immune interactions through intracellular signaling pathways and antioxidant enzyme activity in the spleen of middle-aged ovariectomized female rats P Kale, A Mohanty, A Patil, M Mishra, UP Pratap, HP Priyanka, ... Journal of neuroimmunology 267 (1-2), 7-15, 2014 | 20 | 2014 |
SETDB1 interactions with PELP1 contributes to breast cancer endocrine therapy resistance Z Liu, J Liu, B Ebrahimi, UP Pratap, Y He, KA Altwegg, W Tang, X Li, Z Lai, ... Breast Cancer Research 24 (1), 26, 2022 | 18 | 2022 |
LIF/LIFR oncogenic signaling is a novel therapeutic target in endometrial cancer W Tang, K Ramasamy, SMA Pillai, B Santhamma, S Konda, ... Cell Death Discovery 7 (1), 216, 2021 | 18 | 2021 |
Estrogen receptor coregulator binding modulator (ERX-11) enhances the activity of CDK4/6 inhibitors against estrogen receptor-positive breast cancers S Viswanadhapalli, S Ma, GR Sareddy, TK Lee, M Li, C Gilbreath, X Liu, ... Breast Cancer Research 21, 1-15, 2019 | 17 | 2019 |
Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress X Liu, S Viswanadhapalli, S Kumar, TK Lee, A Moore, S Ma, L Chen, ... Nature Cancer 3 (7), 866-884, 2022 | 16 | 2022 |
LIFR inhibition enhances the therapeutic efficacy of HDAC inhibitors in triple negative breast cancer M Li, S Viswanadhapalli, B Santhamma, UP Pratap, Y Luo, J Liu, ... Communications biology 4 (1), 1235, 2021 | 16 | 2021 |
Interaction of transcription factor AP‐2 gamma with proto‐oncogene PELP1 promotes tumorigenesis by enhancing RET signaling J Liu, Z Liu, M Li, W Tang, UP Pratap, Y Luo, KA Altwegg, X Li, Y Zou, ... Molecular oncology 15 (4), 1146-1161, 2021 | 15 | 2021 |
PELP1 promotes glioblastoma progression by enhancing Wnt/β-catenin signaling GR Sareddy, UP Pratap, S Viswanadhapalli, PP Venkata, BC Nair, ... Neuro-Oncology Advances 1 (1), vdz042, 2019 | 14 | 2019 |
Therapeutic targeting of ovarian cancer stem cells using estrogen receptor beta agonist Y He, S Alejo, PP Venkata, JD Johnson, I Loeffel, UP Pratap, Y Zou, Z Lai, ... International journal of molecular sciences 23 (13), 7159, 2022 | 13 | 2022 |
KDM1A inhibition augments the efficacy of rapamycin for the treatment of endometrial cancer PP Venkata, Y Chen, S Alejo, Y He, BE Palacios, I Loeffel, J Liu, ... Cancer letters 524, 219-231, 2022 | 13 | 2022 |