Imbalanced host response to SARS-CoV-2 drives development of COVID-19 D Blanco-Melo, BE Nilsson-Payant, WC Liu, S Uhl, D Hoagland, R Møller, ... Cell 181 (5), 1036-1045. e9, 2020 | 4159 | 2020 |
Triggering the interferon antiviral response through an IKK-related pathway S Sharma, B tenOever, N Grandvaux, GP Zhou, R Lin, J Hiscott Science 300 (5622), 1148-1151, 2003 | 1834 | 2003 |
VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents DF Stojdl, BD Lichty, JM Paterson, AT Power, S Knowles, R Marius, ... Cancer cell 4 (4), 263-275, 2003 | 966 | 2003 |
Identification of required host factors for SARS-CoV-2 infection in human cells Z Daniloski, TX Jordan, HH Wessels, DA Hoagland, S Kasela, M Legut, ... Cell 184 (1), 92-105. e16, 2021 | 518 | 2021 |
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids Y Han, X Duan, L Yang, BE Nilsson-Payant, P Wang, F Duan, X Tang, ... Nature 589 (7841), 270-275, 2021 | 476 | 2021 |
Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity BR Tenoever, SL Ng, M Chua, ... Science 315, 1274-8, 2007 | 423 | 2007 |
DAI senses influenza A virus genomic RNA and activates RIPK3-dependent cell death RJ Thapa, JP Ingram, KB Ragan, S Nogusa, DF Boyd, AA Benitez, ... Cell host & microbe 20 (5), 674-681, 2016 | 353 | 2016 |
BR tenOever, N. Grandvaux, GP Zhou, R S Sharma, R Benjamin Lin, and J. Hiscott 524, 1148-51, 2003 | 343 | 2003 |
Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA MJ Servant, B tenOever, D Duguay, R Lin, J Hiscott Journal of Biological Chemistry 278 (11), 9441-9447, 2003 | 270 | 2003 |
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics L Si, H Bai, M Rodas, W Cao, CY Oh, A Jiang, R Moller, D Hoagland, ... Nature biomedical engineering 5 (8), 815-829, 2021 | 268 | 2021 |
Influenza A virus-generated small RNAs regulate the switch from transcription to replication JT Perez, A Varble, R Sachidanandam, I Zlatev, M Manoharan, ... Proceedings of the National Academy of Sciences 107 (25), 11525-11530, 2010 | 265 | 2010 |
Viruses and microRNAs: RISCy interactions with serious consequences BR Cullen Genes & development 25 (18), 1881-1894, 2011 | 248 | 2011 |
Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3 MJ Servant, B tenOever, C LePage, L Conti, S Gessani, I Julkunen, R Lin, ... Journal of Biological Chemistry 276 (1), 355-363, 2001 | 246 | 2001 |
Activation of TBK1 and IKKε kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity B tenOever, S Sharma, W Zou, Q Sun, N Grandvaux, I Julkunen, H Hemmi, ... Journal of virology 78 (19), 10636-10649, 2004 | 228 | 2004 |
Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation B tenOever, MJ Servant, N Grandvaux, R Lin, J Hiscott Journal of virology 76 (8), 3659-3669, 2002 | 224 | 2002 |
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types Z Daniloski, TX Jordan, JK Ilmain, X Guo, G Bhabha, BR TenOever, ... Elife 10, e65365, 2021 | 215 | 2021 |
Influenza A virus transmission bottlenecks are defined by infection route and recipient host A Varble, RA Albrecht, S Backes, M Crumiller, NM Bouvier, D Sachs, ... Cell host & microbe 16 (5), 691-700, 2014 | 215 | 2014 |
SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems D Blanco-Melo, BE Nilsson-Payant, WC Liu, R Møller, M Panis, D Sachs, ... BioRxiv, 2020.03. 24.004655, 2020 | 210 | 2020 |
MicroRNA-mediated species-specific attenuation of influenza A virus JT Perez, AM Pham, MH Lorini, MA Chua, J Steel, BR TenOever Nature biotechnology 27 (6), 572-576, 2009 | 182 | 2009 |
The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon M Laurent-Rolle, J Morrison, R Rajsbaum, JML Macleod, G Pisanelli, ... Cell host & microbe 16 (3), 314-327, 2014 | 170 | 2014 |